Is Depo Medrol Safe for Cats?

Depo Medrol is a steroid that is commonly used to reduce inflammation caused by many different conditions. It includes many benefits and side effects, but if not administered properly can cause severe damage to the body. The controversy surrounding the use of Depo Medrol in cats has caused many owners to ask “Can Depo Medrol put a cat to sleep?”

Depo Medrol Killed My Cat

“I’ve read the other reviews, and I’m posting this because I have to add my voice to the chorus. My cat had a bad allergic reaction to a shot of Depo Medrol. He had been given it in the past with no problem, but this time was different. After he was given it, he became very lethargic and hard to rouse. He eventually died.”

“My 8-year-old cat, Vinnie, was prescribed Depo Medrol by my vet last month after Vinnie began licking his paws and pulling out his fur. My vet diagnosed him with allergies and gave him the shot to treat them. A week later Vinnie began throwing up blood. I took him to the vet immediately where they did blood work and an x-ray. Everything appeared normal so they sent me home with anti-nausea medication for Vinnie. The next day he had a seizure, so back to the vet we went.

Vinnie was in kidney failure caused by the Depo Medrol shot he received a week earlier. The only chance for survival was immediate dialysis as well as IV fluids for four days at an animal hospital 100 miles from my home (the closest one). After six days on IV fluids and dialysis, Vinnie started to show signs of improvement, but it was short-lived. He went into cardiac arrest and died two days later.”

Is Depo Medrol toxic to cats?

Depo-Medrol is very effective in the treatment of several inflammatory conditions in pets, including arthritis, musculoskeletal disorders, and skin problems. However, it does have some potential side effects.

Allergic reactions are also possible, it’s likely to cause death in a cat if left untreated. The more serious side effects include kidney or liver failure, pancreatitis, and stomach ulcers. These are rare but they do happen.

If your cat gets a dose of Depo Medrol and then has an adverse reaction, you should call your veterinarian immediately. They may recommend taking the cat to an emergency clinic if the reaction is severe enough.

“My cat has just recovered from a bad bout with Depo Medrol. He was put on it for an allergy-related skin condition. After his second shot, he was not himself at all – he was so lethargic and had no energy or interest in anything. I took him off the shots and shortly (a couple of days) after that he started to be himself again.

He is still on prednisone, which seems to be helping him while we are trying to find out what is causing the allergy. I am sure that it is something in his diet as he is an indoor cat and has nothing else in his environment that could be causing it. I am going to have him tested for food allergies, but meanwhile am trying different foods and supplements to see if anything helps.”

What are the side effects of Depo Medrol in cats?

As with any medication, there are potential side effects of Depo-Medrol in cats. Potential side effects may include:

  • Increased thirst
  • Increased appetite
  • Increased urination
  • Weight gain
  • Hair loss
  • Vomiting

There are many uses for Depo Medrol and it has been considered safe and effective when used responsibly by your veterinarian. If you have any further questions about the specific use of Depo Medrol in your pet’s case, please contact your veterinarian for further guidance.

Can Depo Medrol make cats sick?

While Glucocorticoids can act as a lifesaving drug in many cases, they may cause serious side effects if administered improperly or in excessive doses. Glucocorticoids should not be given to cats that are dehydrated, have poor circulation or heart failure, have an infection anywhere in their body (especially fungal infections), or have had recent abdominal surgery.

Like many drugs, Depo Medrol has some side effects when used long-term. Depo can cause Cushing’s disease and ulcers in the alimentary canal. It should never be given to pregnant cats or cats being treated for certain types of mange, hypothyroidism, or pancreatitis without careful consideration. The risk of side effects increases with dose and duration of treatment.

Depo-Medrol reviews

“I have been using Depo-Medrol for my cat on a regular basis for the past year. I use it as an anti-inflammatory and to help with his arthritis. It does a great job of helping him to be more comfortable and active. He has no negative side effects from taking the medication. We have used other brands of this same product in the past, but I have found Depo-Medrol to work the best and have the lowest cost.”

“I give this to my cat for his arthritis. He is about 12 years old, and the vet recommended it for him. It works great! We did the prednisolone first and that worked too, but he had stomach issues with it, so we switched to this. The only thing with this is that it can cause your cat to be hungrier. I have no idea if that’s because of the Medrol or because they’re older and just eat more as they get older anyway. I do know my cat has a pretty ravenous appetite now, and he was never much of a foodie before. His arthritis is definitely better though and he’s not in pain anymore.”

Conclusion of Depo Medrol for cats

In conclusion, Depo Medrol is a safe drug that can treat many different conditions in cats. Given its anti-inflammatory properties, it can reduce pain and swelling of the joints. As a steroid, it can also be used to reduce the immune system’s response to allergies or other foreign bodies. However, this drug should be avoided in cats with liver or kidney problems as well as pregnant females and kittens. If you have any further questions about Depo Medrol for cats or would like to discuss your cat’s treatment options, please contact your veterinarian.


Hannah Elizabeth is an English animal behavior author, having written for several online publications. With a degree in Animal Behaviour and over a decade of practical animal husbandry experience, Hannah's articles cover everything from pet care to wildlife conservation. When she isn't creating content for blog posts, Hannah enjoys long walks with her Rottweiler cross Senna, reading fantasy novels and breeding aquarium shrimp.

Leave a Reply

Your email address will not be published.

Back to Top