5 Allergy Med for Dogs: What is The Best Allergy Medicine for My Dog?

I have scoured the research and reviewed the data on different antihistamines in order to shine a light on the allergy medicine that works best for dogs with allergies.

Best Allergy Med for Dogs

What is the most effective antihistamine for dogs?

While there are several different types of antihistamines available, most veterinarians recommend using Benadryl for dogs with allergies because it’s inexpensive, easy to administer, and well-tolerated by most pets.

  1. Benadryl
  2. Zyrtec
  3. Claritin
  4. ChlorTrimeton
  5. Tavist

Is Zyrtec or Benadryl better for dogs?

Benadryl and Zyrtec are two antihistamines that veterinarians often prescribe for dogs with allergies.

Benadryl is an older medication that is still available over the counter. It has been around for many years and has a good safety record. Benadryl works well for many dogs, but it does have some side effects.

Zyrtec is a newer antihistamine that was developed specifically for humans. It has fewer side effects than other antihistamines, and it’s generally well tolerated by most dogs.

As with all medicines, there are pros and cons to each option.

Benadryl can be given every 8 or 12 hours while Zyrtec can only be given once a day. Zyrtec also has a longer half-life than Benadryl so it stays in the bloodstream longer.

Benadryl has been around longer, so it’s more familiar to vets and owners alike. Both have many different forms — liquid, tablet, chewable tablet, and ointment — so you should be able to find something that works best for your dog’s needs and situation.

Benadryl and Zyrtec are both safe medications when used at recommended dosages and frequencies, but they do have some side effects.

  • Vomiting
  • Diarrhea
  • Lethargy or sleepiness
  • Restlessness or agitation
  • Dry mouth
  • Constipation
  • Excessive drooling

What do vets prescribe for dog skin allergies?

The severity of the condition will determine how treatment will be approached. Here are some common medications that you can give a dog for severe skin allergies:


Antihistamines block histamine production and help relieve itching caused by allergic reactions.

Most antihistamines come as tablets or liquids. Some of them are also available in topical form, which can be applied directly onto the skin to help relieve itching and scratching.

Don’t give these medications without consulting your vet first if your dog has any other health problems such as kidney, liver, or heart disease.


Corticosteroids aren’t safe for long-term use because they can cause side effects such as weakened immune systems, gastrointestinal bleeding, and behavioral changes.

If your pet needs long-term treatment for allergies, talk to your vet about switching to another medication.

Conclusion of allergy medicine for dogs with allergies

When it comes to treating your dog’s allergies, there are many things you can do. From changing your dog’s diet to using natural remedies, the options are endless. However, one of the most effective ways to treat your dog’s allergies is by giving them an antihistamine.

It is important that you choose an antihistamine that is safe for dogs and will not harm them in any way.

Can I Give My Dog Human Allergy Medication?
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Hannah Elizabeth is an English animal behavior author, having written for several online publications. With a degree in Animal Behaviour and over a decade of practical animal husbandry experience, Hannah's articles cover everything from pet care to wildlife conservation. When she isn't creating content for blog posts, Hannah enjoys long walks with her Rottweiler cross Senna, reading fantasy novels and breeding aquarium shrimp.

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