Apoquel and Zyrtec for Dogs?
It is important to carefully consider any medication that you give to your dog, including the potential risks and benefits. One question that may come up is whether it is safe to give your dog both Apoquel and Zyrtec together.

Can I give my dog Apoquel and Zyrtec together?
Pros:
Both Apoquel and Zyrtec are effective at relieving allergy symptoms in dogs, so combining them may provide even more relief for your dog.
Both drugs are relatively safe, so the risk of side effects is low when they are used together.
Both drugs are available in pill form, so it is easy to give them to your dog together.
Cons:
Apoquel and Zyrtec may interact with other medications your dog is taking, so it is important to inform your veterinarian of all medications your dog is currently taking.
Both drugs are relatively expensive, so giving them together may increase the cost of treatment.
Both drugs may cause side effects in some dogs, such as drowsiness or upset stomach, so you may need to monitor your dog closely when giving them together.
Why is my dog still itching on Apoquel?
There are a few potential reasons why your dog may still be itching even while taking Apoquel. Here are some possible explanations and advice for addressing the issue:
The underlying cause of the itching has not been properly addressed
Apoquel helps reduce itchiness in dogs with allergies or other skin conditions. However, it does not address the root cause of the itching. If your dog has an allergy or skin condition, it is important to properly diagnose and treat the underlying issue in order to fully resolve the itching.
Your dog is experiencing a secondary infection
Sometimes, dogs that are constantly scratching and biting at their skin can develop secondary infections, such as bacterial or fungal infections. These infections can cause additional itching and discomfort and may need to be treated with antibiotics or antifungal medication.
The dosage of Apoquel may not be correct
It is important to follow your veterinarian’s instructions for administering Apoquel and to monitor your dog’s response to the medication. If your dog is still itching, it may be necessary to adjust the dosage or try a different treatment option.
Your dog may be experiencing an adverse reaction to Apoquel
While rare, it is possible for a dog to have an adverse reaction to Apoquel. If you notice any unusual side effects, such as vomiting, diarrhea, or changes in behavior, it is important to contact your veterinarian immediately.
Apoquel alternatives
There are several Apoquel alternatives that can provide safe and effective relief for your pet’s allergies.
Cyclosporine
Cyclosporine is a medication that works similarly to Apoquel in treating allergies. It works by suppressing the immune system’s response to allergens, thereby reducing itching and inflammation. Although it may take longer to see results, Cyclosporine is known for its long-term benefits and effectiveness.
Benadryl
Benadryl is an over-the-counter antihistamine that is safe for dogs when used in appropriate doses. It is effective in relieving itching and can also help with other allergy symptoms such as sneezing and runny nose. However, it is important to note that Benadryl can cause drowsiness in dogs, so it’s best to consult with your veterinarian before using it.
Omega-3 Fatty Acids
Omega-3 fatty acids are essential nutrients that can help reduce inflammation in the body. They can be found in fish oil supplements, which are often recommended for dogs with skin conditions or allergies. Not only do they provide relief for your pet’s itching, but they also promote overall health by improving coat quality and reducing the risk of heart disease.
Atopica
Atopica is another medication that is commonly prescribed to treat allergies in dogs. It works by suppressing the immune system’s response to allergens, similar to Cyclosporine. It may take longer to see results, but it is known for its effectiveness in reducing itching and inflammation. It’s important to note that Atopica may have some side effects such as vomiting, diarrhea, and loss of appetite, so it’s best to monitor your pet closely when using it.
Allergy Shots
Allergy shots, also known as immunotherapy, involve injecting small amounts of allergens into your pet’s body to help build up their immune system’s tolerance to them. Over time, your pet may become less sensitive to the allergens, reducing their allergy symptoms. This option may take several months to show results, but it can be a long-term solution for pets with severe allergies.
Natural Remedies
Some pet owners prefer to use natural remedies to treat their pet’s allergies. These may include herbal supplements, such as chamomile or turmeric, or homeopathic remedies like arnica or calendula. While these options may be less expensive than prescription medications, it’s important to note that their effectiveness has not been extensively studied, and they may not work for every pet.
Change in Diet
Sometimes, allergies can be caused or aggravated by certain foods. Changing your pet’s diet may help alleviate their allergy symptoms. For example, a grain-free or hypoallergenic diet may be recommended for dogs with food allergies. It’s important to work with your veterinarian to determine the best diet for your pet and to ensure that they are getting all the necessary nutrients.
Steroids
Steroids, such as prednisone or dexamethasone, may be prescribed to treat severe allergies or to provide quick relief in emergency situations. However, they should be used with caution as they can have significant side effects, including increased thirst, appetite, and urination, as well as potential long-term effects on your pet’s health.
Topical Treatments
Topical treatments, such as medicated shampoos or sprays, can be effective in relieving itching and irritation caused by allergies. These products contain ingredients like hydrocortisone or aloe vera, which can soothe the skin and reduce inflammation. They can also help to prevent secondary bacterial infections from developing.
FAQs about Zyrtec and Apoquel for dogs
Here are some frequently asked questions about these medications:
What is Zyrtec?
Zyrtec, also known as cetirizine, is an antihistamine medication commonly used to treat allergies in humans. However, it can also be prescribed by veterinarians to help manage allergy symptoms in dogs. Zyrtec works by blocking the effects of histamine, which is a chemical that causes allergy symptoms such as itching, sneezing, and watery eyes.
Is Zyrtec safe for dogs?
Yes, Zyrtec is generally considered safe for dogs. However, it’s important to consult with your veterinarian before giving your dog any medication. Dosage and frequency can vary depending on your dog’s size, breed, and specific allergy symptoms. Additionally, certain dogs may have pre-existing conditions or sensitivities that could make Zyrtec unsuitable for them.
What is Apoquel?
Apoquel, also known as oclacitinib, is a prescription medication specifically designed to treat itching and inflammation caused by allergies in dogs. Unlike Zyrtec, which is an antihistamine, Apoquel works by blocking certain enzymes that contribute to the inflammatory response. This can provide faster relief of allergy symptoms than traditional antihistamines.
Is Apoquel safe for dogs?
Yes, Apoquel is generally considered safe for dogs. However, as with any medication, there can be potential side effects. Common side effects of Apoquel include vomiting, diarrhea, and decreased appetite. In rare cases, more serious side effects such as infections or lymphoma have been reported. As with Zyrtec, it’s important to consult with your veterinarian to determine if Apoquel is safe and appropriate for your dog.
Can I give my dog Zyrtec and Apoquel together?
It’s not recommended to give your dog Zyrtec and Apoquel together without consulting with your veterinarian first. While both medications are used to treat allergy symptoms, they work differently and can have different side effects. Your veterinarian can help determine the best course of treatment for your dog’s specific allergy symptoms.
How long does it take for Zyrtec and Apoquel to start working?
The time it takes for Zyrtec and Apoquel to start working can vary depending on the severity of your dog’s allergy symptoms. Zyrtec typically takes about 30 minutes to start working and can provide relief for up to 24 hours. Apoquel can start providing relief within hours of the first dose and can provide continuous relief for up to 24 hours.
Can Zyrtec and Apoquel be used for other conditions besides allergies?
While Zyrtec and Apoquel are primarily used to manage allergy symptoms in dogs, they may also be used to treat other conditions. For example, Zyrtec can be used to manage itching caused by skin infections or parasites. Apoquel may also be used to manage itching caused by non-allergic skin conditions, such as flea allergy dermatitis. However, it’s important to consult with your veterinarian before using either medication for a condition other than allergies.
Can Zyrtec and Apoquel be used together with other medications?
It’s important to talk to your veterinarian about any other medications your dog is taking before starting Zyrtec or Apoquel. Certain medications, such as steroids or other antihistamines, may interact with Zyrtec or Apoquel and cause unwanted side effects. Your veterinarian can help determine if it’s safe to use these medications together.
What are some alternative treatments for allergies in dogs?
While Zyrtec and Apoquel can be effective in managing allergy symptoms in dogs, there are also alternative treatments available. These may include dietary changes, such as a hypoallergenic or limited-ingredient diet, or supplements such as omega-3 fatty acids. Additionally, environmental changes such as keeping your home free of dust or pollen can also help alleviate allergy symptoms. Your veterinarian can help determine which treatment options are best suited for your dog’s specific allergy symptoms.
How can I tell if my dog has allergies?
Common signs of allergies in dogs include itching, scratching, chewing or licking at their skin, red or irritated skin, and ear infections. Additionally, dogs with allergies may also have digestive issues such as vomiting or diarrhea. If you suspect your dog may have allergies, it’s important to consult with your veterinarian to determine the underlying cause and the best course of treatment.
Are there any side effects to watch for with Zyrtec or Apoquel?
Like any medication, Zyrtec and Apoquel can cause side effects in some dogs. Common side effects of Zyrtec may include drowsiness, dry mouth, or gastrointestinal issues such as vomiting or diarrhea. Common side effects of Apoquel may include vomiting, diarrhea, decreased appetite, or lethargy. If you notice any concerning symptoms or side effects in your dog after starting either medication, it’s important to contact your veterinarian right away.
Can Zyrtec or Apoquel be used long-term?
Both Zyrtec and Apoquel can be used long-term to manage chronic allergy symptoms in dogs. However, it’s important to monitor your dog for any potential side effects or changes in their condition, and to consult with your veterinarian regularly to ensure that the medication is still appropriate and effective for your dog’s needs.
How often should I give my dog Zyrtec or Apoquel?
The frequency and dosage of Zyrtec and Apoquel can vary depending on your dog’s size, breed, and specific allergy symptoms. Your veterinarian can provide specific dosing instructions based on your dog’s individual needs. In general, Zyrtec is typically given once a day, while Apoquel may be given once or twice a day.
Are there any dogs who should not take Zyrtec or Apoquel?
While Zyrtec and Apoquel are generally safe for most dogs, there are some dogs who may not be good candidates for these medications. For example, dogs with liver or kidney disease may not be able to tolerate certain medications, and dogs with certain medical conditions or who are taking certain medications may have increased risk of side effects. It’s important to consult with your veterinarian to determine if Zyrtec or Apoquel are safe and appropriate for your dog.