Can You Give a Dog Melatonin to Calm Them Down?

Melatonin is a hormone that helps regulate sleep and wake cycles in animals and humans. It is commonly used as a natural sleep aid for humans, but it can also be used to help dogs with anxiety or other behavioral issues.


  • Melatonin is a natural hormone that can help regulate the sleep-wake cycle in dogs, making it a potentially effective option for dogs with anxiety or insomnia.
  • It is non-habit forming and has few side effects, making it a safe option for long-term use.
  • It can be used in conjunction with other medications or behavioral therapies for a more comprehensive approach to treating anxiety in dogs.


  • Melatonin should only be used under the guidance of a veterinarian, as the appropriate dosage can vary based on the individual dog’s size and needs.
  • It may not be effective for all dogs, and may not address the underlying cause of the anxiety or insomnia.
  • Some dogs may experience side effects such as grogginess or disorientation after taking melatonin, which can be unsafe if the dog needs to be able to respond to commands or navigate unfamiliar environments.

How much melatonin can I give my dog chart

A general guideline for melatonin dosage in dogs is 0.5-3 mg per 20 pounds of body weight. However, it’s important to consult with your veterinarian before giving your dog any medication, as they will be able to take into account any underlying health conditions or other medications your dog may be taking.

Melatonin should not be used long-term as it can cause negative side effects and may not be effective in the long term. It’s best to use melatonin as a short-term solution for insomnia or other sleep issues and work with your veterinarian to find a long-term solution.

Melatonin is available in various forms such as tablets, capsules, and liquids. The form of melatonin will affect the dosage, so it’s important to consult with your veterinarian or the product packaging for the appropriate dosage.

How long does it take for melatonin to work in dogs?

In general, melatonin begins to work within 30 minutes to an hour after it is given to a dog. However, some dogs may not see the full effects for up to 2 hours. It’s also important to note that the effects of melatonin can last for different amounts of time for different dogs, typically around 6-8 hours.

What are the side effects of melatonin for dogs?

Here are some potential side effects of melatonin for dogs:

  • Drowsiness: Melatonin is a sleep-inducing hormone, so it’s not surprising that it can cause drowsiness in dogs. This can be beneficial for dogs who have trouble sleeping, but it can also make them lethargic during the day.
  • Disorientation: Some dogs may experience disorientation or confusion after taking melatonin. This can be especially pronounced in older dogs or those with cognitive impairment.
  • Digestive issues: Some dogs may experience stomach upset or diarrhea after taking melatonin. This can be due to the dog’s sensitivity to the medication or a reaction to the fillers or binders in the melatonin supplement.
  • Allergic reactions: Like any medication, melatonin can cause allergic reactions in some dogs. Symptoms may include hives, itching, or swelling of the face or paws.
  • Interaction with other medications: Melatonin can interact with other medications, including antidepressants, blood pressure medications, and blood thinners. It’s important to talk to your vet about any medications your dog is taking before starting melatonin.

Can I give my dog melatonin every night?

One study found that melatonin was safe for dogs when used at the recommended dose for short-term use (up to 4 weeks). However, long-term use and higher doses may cause side effects such as lethargy, loss of appetite, and changes in hormone levels. Additionally, melatonin may interact with other medications that your dog is taking, so it is important to talk to your vet before giving your dog any supplements.

Melatonin may not be appropriate for all dogs. For example, dogs with certain medical conditions or those taking certain medications may not be able to take melatonin. Therefore, it is important to consult with your vet to determine if melatonin is safe and appropriate for your furry friend.

Melatonin is not a cure-all, it is a symptom reliever, if the underlying cause of your dog’s sleep issues is not addressed, it will be still present after giving Melatonin.

What kind of melatonin can I give my dog?

When looking to give your dog melatonin, it’s essential to choose a product that is specifically formulated for canines.

One of the options available is chewable melatonin tablets. These can be a convenient way to give your dog melatonin as they are easy to administer and can be given as a treat.

Another option is liquid melatonin. This form of the hormone is often easier to administer and can be added to your dog’s food or water. However, it’s essential to check the dosage instructions carefully as liquid melatonin can be more potent than chewable tablets.

It’s important to check the ingredients of any melatonin product you’re considering. Some melatonin supplements may contain other substances that may not be safe for dogs. For example, some products may contain xylitol, which is toxic to dogs.

What happens if I give my dog too much melatonin?

If you notice any unusual symptoms or changes in your dog’s behavior after giving them melatonin, seek medical attention immediately.

  • Drowsiness and sedation: Melatonin is a natural hormone that helps regulate sleep-wake cycles. Giving your dog too much of it can cause excessive drowsiness and sedation, making it difficult for them to stay awake or engage in normal activities.
  • Loss of appetite: Melatonin can also affect appetite, so a dog that receives too much of it may lose interest in food and have difficulty maintaining a healthy weight.
  • Disorientation and confusion: High doses of melatonin can also cause disorientation and confusion in dogs, making it difficult for them to navigate their environment or respond to commands.
  • Hormonal imbalances: Melatonin is a hormone that plays a crucial role in regulating various bodily functions. Giving your dog too much of it can disrupt these functions and lead to hormonal imbalances that can have serious health consequences.
  • Interference with other medications: If your dog is taking other medications, giving them too much melatonin can interfere with their effectiveness or cause dangerous interactions.

Conclusion of melatonin for dogs

Melatonin is a hormone that helps regulate sleep-wake cycles in dogs, and it is often used as a supplement to help dogs with insomnia or other sleep disorders.


  • Melatonin can be helpful for dogs that have trouble sleeping, as it can help them to fall asleep faster and stay asleep longer.
  • Melatonin is generally considered safe for dogs, with few reported side effects.
  • Melatonin is available over-the-counter, so it is easy to obtain.


  • Melatonin can interact with other medications that your dog is taking, so it’s important to talk to your vet before giving it to your dog.
  • Long-term use of melatonin is not recommended, as it can disrupt the body’s natural production of melatonin.
  • Melatonin can cause drowsiness, so it should not be given to dogs that will be driving or operating heavy machinery.

Side effects:

  • The most common side effects of melatonin in dogs are drowsiness, dizziness, and dry mouth.
  • In rare cases, melatonin may cause more serious side effects such as seizures or allergic reactions.


  • Melatonin is considered safe for dogs when used as directed, but high doses can be toxic.
  • Signs of melatonin toxicity in dogs include restlessness, disorientation, and rapid heartbeat.

Drug interactions:

  • Melatonin can interact with other medications, such as antidepressants, blood pressure medication and blood thinners, so it is important to talk to your vet before giving it to your dog.


  • Melatonin is not recommended for dogs that are pregnant or nursing.
  • Melatonin should not be given to dogs with a history of seizures or other neurological disorders.

Research and study:

  • Melatonin has been the subject of a number of studies in dogs, but more research is needed to fully understand its effects and potential risks.


  • There are other options available for helping dogs with sleep disorders, such as behavioral training, environmental changes, and other supplements. Talk to your vet to find the best option for your furry friend.

Hannah Elizabeth is an English animal behavior author, having written for several online publications. With a degree in Animal Behaviour and over a decade of practical animal husbandry experience, Hannah's articles cover everything from pet care to wildlife conservation. When she isn't creating content for blog posts, Hannah enjoys long walks with her Rottweiler cross Senna, reading fantasy novels and breeding aquarium shrimp.

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