Galliprant 100 mg for Dogs

Galliprant is an FDA-approved NSAID specifically designed to treat mild to moderate pain associated with osteoarthritis in dogs. It blocks the receptor called prostaglandin E2 (EP4), primarily responsible for inflammation and pain in arthritic joints. By doing so, Galliprant eases the discomfort, thereby improving the quality of life for dogs suffering from osteoarthritis.

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Benefits of Galliprant for Dogs

1. Targeted Pain Relief: The main advantage of Galliprant is its ability to target specific sites of inflammation, offering relief without disrupting other physiological processes, a common issue with traditional NSAIDs.

2. Lower Risk of Side Effects: As it specifically targets the EP4 receptor, Galliprant has a lower risk of causing gastrointestinal, kidney, or liver problems often associated with other NSAIDs.

3. Easy to Administer: Available in beef-flavored tablets, most dogs take Galliprant without fuss, making it easier for pet owners to maintain a consistent treatment plan.

Potential Side Effects of Galliprant

As with any medication, Galliprant has potential side effects. These may include vomiting, diarrhea, decreased appetite, or lethargy. If any of these signs are persistent or become severe, a vet should be contacted immediately.

Galliprant Reviews: What Do Dog Owners Say?

A delve into forums and online communities such as Reddit offers an insight into real-life experiences with Galliprant.

1. Positive Feedback: Many pet owners report a noticeable improvement in their dog’s mobility and overall mood after starting Galliprant. Owners appreciate that the drug is easy to administer and has fewer side effects than other medications.

2. Concerns About Cost: A recurring issue brought up by dog owners is the cost of Galliprant. The drug is more expensive than traditional NSAIDs, which may make long-term treatment challenging for some pet owners.

3. Mixed Reviews on Side Effects: Some pet owners share experiences of minor side effects, like soft stools or mild lethargy. However, these are generally rare and often subside with continued use or dosage adjustment.

Galliprant Administration and Dosage

The dosage and administration of Galliprant are straightforward. Galliprant is provided as a flavored tablet, a feature that is widely appreciated by pet owners for its easy administration. The recommended dosage of Galliprant for dogs is 0.9 mg/lb (2 mg/kg) once a day. The drug should ideally be given with food, which can aid in minimizing potential gastrointestinal side effects.

It’s important to follow the vet’s instructions regarding the dose and frequency of Galliprant. Accidental overdose can cause serious health complications, and skipping doses may render the medication ineffective.

Galliprant Interactions and Precautions

As an NSAID, Galliprant could interact negatively with certain other medications. For instance, it is typically not recommended to be used in conjunction with corticosteroids or other NSAIDs. If your dog is on any other medication, be sure to discuss this with your vet to avoid possible harmful interactions.

Galliprant should not be used in dogs who are allergic to grapiprant. Additionally, caution is advised for dogs with a history of cardiac disease. Pregnant or nursing dogs, as well as puppies less than 9 months of age, should not be given Galliprant.

Cost and Availability of Galliprant

One of the most voiced concerns about Galliprant is its cost. Galliprant is priced higher than traditional NSAIDs, making it a significant consideration for pet owners, especially for long-term use. The cost can also vary depending on the dog’s weight, as larger dogs will require higher dosages.

Despite the cost, many pet owners find the benefits of Galliprant worthwhile, reporting noticeable improvements in their dogs’ quality of life.

Galliprant is a prescription medication, so it’s not available over the counter. You’ll need a prescription from a vet to purchase it. It’s widely available at most veterinary clinics and can also be ordered from online pet pharmacies.

Galliprant and Quality of Life

The ultimate goal of any treatment for osteoarthritis is to improve the patient’s quality of life. Dog owners often report significant improvements in their pets’ behavior, mobility, and overall well-being after beginning a Galliprant regimen.

Pets who were once lethargic due to pain have been reported to be more active and engaged in family activities. Improved mobility, less stiffness, and an overall happier demeanor are frequently mentioned in reviews by pet owners. These improvements can significantly enhance the pet’s quality of life and the overall pet-owner bond.


1. What is the active ingredient in Galliprant?

The active ingredient in Galliprant is grapiprant. This compound specifically targets and blocks the prostaglandin E2 (EP4) receptor, which is primarily responsible for inflammation and pain associated with osteoarthritis in dogs.

2. Can Galliprant cause behavioral changes in dogs?

While it’s relatively rare, some owners have reported slight behavioral changes in their dogs while taking Galliprant, such as increased lethargy. If you notice substantial changes in your dog’s behavior after starting this medication, consult your vet to discuss possible adjustments to the dosage or alternative treatments.

3. Is Galliprant safe for long-term use in dogs?

Galliprant is typically considered safe for long-term use in treating osteoarthritis pain in dogs. However, regular vet check-ups are essential to monitor your dog’s response to the medication and adjust the dosage as necessary.

4. Can Galliprant be used alongside other medications?

Galliprant should not be administered concurrently with some medications, including other NSAIDs or corticosteroids, due to the risk of harmful drug interactions. Always inform your vet of any other medications your dog is currently taking before starting Galliprant.

5. How quickly does Galliprant start working?

Owners often report seeing improvement in their dog’s symptoms within a few days to a week of starting Galliprant. However, the exact timeline can vary based on the individual dog and the severity of their symptoms.

6. Does Galliprant require blood monitoring?

Unlike some other NSAIDs, Galliprant does not generally require regular blood monitoring. However, vets may recommend periodic check-ups to ensure the medication is well-tolerated and effective in managing your dog’s osteoarthritis pain.

7. Can Galliprant cause liver or kidney damage in dogs?

The risk of liver or kidney damage is significantly lower with Galliprant than with traditional NSAIDs because Galliprant specifically targets the EP4 receptor, reducing systemic side effects. That said, in rare cases, Galliprant may cause elevated levels of liver or kidney enzymes. Regular vet check-ups can help detect and address any potential issues early.

8. Are there any special storage instructions for Galliprant?

Galliprant should be stored at room temperature, typically between 68°F to 77°F (20°C to 25°C). It should be kept in a dry place and out of direct sunlight. Always keep the medication out of reach of children and other pets.

9. Is Galliprant suitable for all breeds of dogs?

Yes, Galliprant can be administered to all breeds of dogs. However, the dosage will depend on the dog’s weight. Your veterinarian will calculate the precise dosage needed for your dog’s specific weight and condition.

10. What if my dog misses a dose of Galliprant?

If your dog misses a dose, give the missed dose as soon as you remember. If it’s near the time for the next dose, skip the missed dose and continue with the regular schedule. Never give your dog two doses at once to make up for a missed one.

11. Can I give Galliprant to my cat?

No, Galliprant is not approved for use in cats. It’s a medication specifically designed for dogs suffering from osteoarthritis. Always consult with a veterinarian before giving any medication to your pets.

12. What should I do if my dog accidentally ingests more than the prescribed amount of Galliprant?

If your dog accidentally ingests more than the prescribed dosage of Galliprant, seek immediate veterinary attention. Overdose can lead to serious health complications, including stomach ulcers, kidney failure, or liver failure.

13. Can I use Galliprant for post-operative pain in dogs?

Galliprant is not approved for the treatment of postoperative pain. It is specifically indicated for the control of pain and inflammation associated with osteoarthritis in dogs.

14. Are there any alternatives to Galliprant for treating arthritis in dogs?

Yes, there are several alternatives to Galliprant for treating arthritis in dogs, including other NSAIDs like carprofen, meloxicam, and deracoxib. There are also non-drug therapies, such as physical therapy, weight management, and joint supplements. It’s important to discuss these options with your vet to find the most suitable solution for your pet.

15. Is it safe to give my dog Galliprant with food?

Yes, it’s generally recommended to administer Galliprant with food to reduce the chance of a gastrointestinal upset. This can also make it easier for your dog to ingest the medication.

16. Can puppies take Galliprant?

Galliprant is approved for use in dogs aged 9 months and older. Always consult your vet before starting any new medication, especially with younger dogs, as their bodies may react differently.

17. Can pregnant or lactating dogs take Galliprant?

The safety of Galliprant has not been evaluated in pregnant, breeding, or lactating dogs. As with all medications, you should discuss the risks and benefits with your vet if your dog is pregnant or nursing.

18. Are there any known drug interactions with Galliprant?

Galliprant should not be used in combination with corticosteroids or other nonsteroidal anti-inflammatory drugs (NSAIDs). If your dog is on other medication, ensure to inform your vet so they can monitor for potential drug interactions.

19. What are the signs of an adverse reaction to Galliprant in dogs?

Signs of an adverse reaction to Galliprant can include vomiting, diarrhea, decreased appetite, and lethargy. In rare instances, it can cause more severe side effects like jaundice or changes in urine color. If you observe any of these signs, stop giving Galliprant and contact your vet immediately.

20. Can Galliprant cause weight gain in dogs?

Weight gain is not a typical side effect of Galliprant. If your dog is gaining weight while on Galliprant, it could be due to reduced physical activity due to pain, or other unrelated factors. Always monitor your dog’s weight and discuss any significant changes with your vet.

21. Can Galliprant be used to treat other types of pain in dogs?

While Galliprant is primarily designed to manage the pain and inflammation associated with osteoarthritis in dogs, it may be used off-label to manage other types of pain. However, this should only be done under the supervision of a vet.

22. Does Galliprant help improve mobility in dogs with osteoarthritis?

Yes, by reducing pain and inflammation caused by osteoarthritis, Galliprant can help improve mobility in affected dogs. However, it’s essential to pair this medication with other management strategies such as weight control, regular exercise, and possibly physical therapy.

23. How should I transition my dog from another NSAID to Galliprant?

If you are switching your dog from another NSAID to Galliprant, it’s important to first discuss this with your vet. They will likely recommend a “washout” period, where you discontinue the old NSAID for a few days before starting Galliprant, to prevent any potential interactions or side effects.

24. Can I crush Galliprant tablets to make it easier for my dog to ingest?

Galliprant tablets are chewable and flavored, making them generally well-accepted by dogs. However, if your dog is having difficulty, consult your vet about the best way to administer the medication. It’s important not to crush or split the tablets without first discussing this with your vet.

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