Galliprant With or Without Food

As pet owners, there’s nothing we wouldn’t do to ensure our furry friends live comfortably, especially when they’re dealing with chronic conditions like osteoarthritis. One of the medications that have emerged as a godsend for dogs suffering from this condition is Galliprant. But, one common question that keeps resurfacing is, “Should Galliprant be given with or without food?”

Understanding Galliprant

Galliprant (grapiprant) is a non-steroidal anti-inflammatory drug (NSAID) that vets often prescribe to manage pain and inflammation associated with osteoarthritis in dogs. It works by targeting and blocking a specific receptor known as the EP4 receptor, the primary mediator of canine osteoarthritis pain and inflammation.

Galliprant: With or Without Food?

A point of contention that many pet owners grapple with is whether to administer Galliprant with or without food. From an official standpoint, Galliprant can be given either way. However, administering it with a meal is often recommended. This is not only because it might increase the absorption of the medication but also because it may reduce the potential for gastrointestinal upset, a common side effect associated with NSAIDs.

Timing Matters: When to Give Galliprant

When should you give your dog Galliprant? This largely depends on your dog’s routine and how it responds to the medication. It’s generally recommended that if the drug is given once daily, it should ideally be administered at the same time each day to maintain a consistent level in your dog’s system. Remember, consistency is key when it comes to administering medication for chronic conditions.

Watching Out for Adverse Reactions

While Galliprant is typically well-tolerated by dogs, it’s essential to monitor your pet for potential adverse reactions. These can include vomiting, diarrhea, loss of appetite, and lethargy. If you notice your dog exhibiting any unusual behavior or symptoms after starting Galliprant, contact your vet immediately.


In conclusion, Galliprant can be given with or without food. However, giving it with a full meal might make the medication more tolerable for your furry friend and potentially increase its absorption. Always remember that each dog is unique, so what works best for one might not work as well for another. As such, it’s crucial to keep an open line of communication with your vet, monitor your dog closely, and adjust the routine as needed.

FAQs: Navigating the Complexities of Galliprant

1. What is Galliprant?

Galliprant (grapiprant) is a non-steroidal anti-inflammatory drug (NSAID) specifically designed for canines. Veterinarians often prescribe it to manage the pain and inflammation associated with osteoarthritis, a chronic condition that affects many dogs, especially in their senior years.

2. Can Galliprant be Administered with Food?

Yes, Galliprant can be given with or without food. Although it doesn’t require food for absorption, administering the drug during mealtime can potentially mitigate the risk of gastrointestinal upset, a side effect common with many NSAIDs. This can also aid in establishing a routine, ensuring consistent administration.

3. Are There Side Effects to Giving Galliprant?

While Galliprant is generally well-tolerated, it’s crucial to monitor your pet for potential adverse reactions. Side effects can range from mild to severe and may include symptoms such as vomiting, diarrhea, decreased appetite, and lethargy. If your pet exhibits any unusual behavior or symptoms after starting Galliprant, contact your vet immediately.

4. Can I Give Galliprant Twice a Day?

Galliprant is typically prescribed as a once-daily medication. However, always adhere to your vet’s instructions regarding the dosing frequency. Do not adjust the dosage or frequency without consulting your vet, as this could potentially lead to an overdose or reduced effectiveness of the medication.

5. How Long Does Galliprant Last in Dogs?

The specific duration Galliprant stays active in a dog’s system can vary based on factors such as the dog’s size, metabolism, and overall health. In general, the effects of a single dose of Galliprant are expected to last for 24 hours, which is why it’s typically prescribed as a once-daily medication.

6. Can Galliprant and Other Medications Be Given Together?

Galliprant can sometimes be administered alongside other medications, depending on the type and the dog’s overall health status. It’s critical to inform your vet about any other medications or supplements your dog is currently taking to avoid possible drug interactions. As a rule of thumb, never combine Galliprant with another NSAID without veterinary supervision, as this can increase the risk of adverse effects.

7. Why Is Galliprant Expensive?

The cost of Galliprant can be attributed to several factors. This includes the costs associated with its research and development, the advanced technology used in its formulation, and its unique mechanism of action. Additionally, as Galliprant is a prescription medication, it must adhere to strict regulations and quality control measures, which can add to the overall cost.

8. Are There Any Alternatives to Galliprant?

Yes, there are several alternatives to Galliprant, including traditional NSAIDs like carprofen and meloxicam, as well as non-drug treatments such as physiotherapy, weight management, and certain dietary supplements. However, the appropriateness of these alternatives depends on your dog’s specific condition and overall health status. Always consult your vet before starting or changing your dog’s medication regimen.

9. What Should I Do If I Miss a Dose of Galliprant?

If you happen to miss giving your dog a dose of Galliprant, administer it as soon as you remember. However, if it’s nearing the time for the next scheduled dose, skip the missed dose and continue with the regular schedule. Avoid giving your dog two doses at once as this can potentially lead to an overdose.

10. How Should Galliprant be Stored?

Galliprant should be stored at room temperature, away from light and moisture. It’s also essential to keep it out of reach of children and pets to prevent accidental ingestion.

11. Does Galliprant Provide Immediate Relief for My Dog?

Every dog’s response to medication is unique, and the time it takes for Galliprant to work can vary. Some dogs might exhibit noticeable improvements within hours, while others may take a few days. If your dog doesn’t show signs of improvement after several days, or if their condition worsens, consult your vet.

12. Can Galliprant Cause Behavioral Changes in My Dog?

Although not common, behavioral changes can occur in some dogs taking Galliprant. These could include increased aggression, anxiety, restlessness, or depression. If you notice any behavioral changes in your dog after starting Galliprant, it’s crucial to consult your vet.

13. Can Puppies Take Galliprant?

Galliprant is approved for use in dogs who are at least 9 months of age and weigh a minimum of 8 pounds. It’s not typically recommended for puppies or small dogs that fall below these criteria. As always, consult with your vet about the most appropriate treatment options for your pet.

14. Is Galliprant Safe for Long-term Use?

Galliprant has been designed for long-term use in dogs suffering from osteoarthritis. However, like any medication, long-term use may come with risks. Regular veterinary check-ups will ensure your dog is tolerating the medication well and it is effectively managing their pain and inflammation.

15. Does Galliprant Cure Arthritis?

No, Galliprant does not cure arthritis. It is a medication designed to manage the symptoms associated with arthritis, such as pain and inflammation. Currently, there is no cure for arthritis in dogs, but symptoms can be effectively managed with appropriate medication, lifestyle changes, and ongoing vet care.

16. Can Galliprant Cause Gastrointestinal Problems in Dogs?

While Galliprant is designed to be gentler on a dog’s stomach than traditional NSAIDs, there’s still a possibility of gastrointestinal problems, although these tend to be less severe. Some dogs might experience vomiting, diarrhea, decreased appetite, or unusual stools. If these symptoms persist or worsen, contact your vet immediately.

17. What Other Medications May Interact With Galliprant?

Galliprant can potentially interact with other medications, including other NSAIDs (such as aspirin or carprofen), corticosteroids (like prednisone), and certain types of drugs used to treat high blood pressure. Always inform your vet about any medications or supplements your dog is taking to avoid any harmful interactions.

18. Can Galliprant be Used in Dogs with Kidney or Liver Disease?

Galliprant’s use in dogs with severe liver or kidney disease has not been thoroughly studied. It’s crucial to discuss your dog’s overall health and medical history with your vet before starting Galliprant. They may choose to monitor your pet’s liver or kidney function more closely while on this medication.

19. Are There Any Breed-Specific Considerations When Using Galliprant?

There are no specific breed restrictions for using Galliprant. However, as different breeds may be more susceptible to certain health conditions, your vet will consider your dog’s breed as part of the overall evaluation before prescribing this medication.

20. What Should I Do If I Think My Dog Has Overdosed on Galliprant?

An overdose of Galliprant may cause severe symptoms such as lethargy, increased thirst, changes in urine production, vomiting, loss of appetite, or abnormal behavior. If you suspect your dog has overdosed, seek immediate veterinary attention.

21. Does Galliprant Affect a Dog’s Weight?

Weight changes are not a common side effect of Galliprant. However, if you notice significant weight gain or loss while your dog is taking this medication, it’s essential to consult your vet as this could indicate an underlying health issue.

22. Can Galliprant Help Improve My Dog’s Mobility?

Yes, by reducing the inflammation and pain associated with osteoarthritis, Galliprant can help improve your dog’s mobility and overall quality of life. However, it’s important to pair this medication with other lifestyle changes like a balanced diet, regular exercise, and maintaining an optimal weight for maximum benefits.

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