Heartgard Plus 26-50

Heartgard Plus is a leading name in heartworm prevention for our furry friends. The “26-50” on the label specifically indicates that it’s formulated for dogs weighing between 26 to 50 pounds. This oral medication not only prevents heartworms but also treats and controls roundworms and hookworms.

The Active Ingredients: Ivermectin and Pyrantel

The efficacy of Heartgard Plus lies in its two active ingredients – Ivermectin and Pyrantel. While Ivermectin prevents heartworm disease by eliminating the tissue stage of heartworm larvae, Pyrantel pamoate, on the other hand, eradicates roundworms and hookworms.

The Safety Profile of Heartgard Plus

Many dog owners have safety concerns when administering medication to their pets. Thankfully, Heartgard is recognized for its safety. The margin of safety is high, meaning that significant overdosing would be required to see toxic effects. Even if your dog is slightly over the weight range, the medication remains effective and safe.

When Your Dog’s Weight Fluctuates

It’s common for a dog’s weight to vary, especially as they grow or due to dietary and health changes. So, if your dog is on the cusp between weight categories, such as weighing 25.3 pounds, they can still take the 1-25lbs dose, but it’s always wise to consult with your veterinarian for precise dosing.

Monthly Protection: A Routine to Remember

Heartgard Plus should be given once a month, every month, all year round. It’s a tasty beef-flavored chewable, which most dogs love, making the monthly routine easier for pet parents. However, don’t consider doubling up on doses without seeking veterinary advice.

The Evolution of Heartworm Prevention

Heartworm disease is dangerous, even deadly, for dogs. As the only canine monthly broad-spectrum heartworm preventative that also carries a label claim for U. stenocephala, Heartgard Plus has positioned itself at the forefront of innovation in heartworm prevention.

Comparative Costs and Where to Buy

The pricing of Heartgard Plus 26-50 can vary depending on where you purchase. Retailers like Costco have been known to offer competitive prices. Always make sure you’re buying from a reputable source to ensure you’re getting genuine medication for your dog.

Final Thoughts

Heartgard Plus 26-50 is an essential tool in the toolkit of responsible dog owners who weigh between 26 to 50 pounds. Its broad-spectrum protection, combined with its safety profile, makes it a popular choice. Always remember to keep up with monthly doses and consult with your vet about any weight or health changes in your dog.


1. How does Heartgard Plus differ from other heartworm preventatives?

Heartgard Plus stands out due to its dual-action against heartworms, roundworms, and hookworms, thanks to its active ingredients, Ivermectin and Pyrantel. While many other preventatives target heartworm larvae, Heartgard Plus offers broader protection, treating and controlling other common intestinal parasites as well.

2. Can I use Heartgard Plus for a puppy?

Yes, Heartgard Plus can be administered to puppies as young as six weeks old. Given the susceptibility of puppies to parasites, starting preventative measures early is crucial.

3. My dog spit out the Heartgard chew. What should I do?

If your dog spits out the chewable, try offering it again, perhaps with a treat or mixed into their food. If they continue to refuse it, consult with your vet. They might offer alternative administration methods or brands.

4. What if I miss a dose?

If you miss a dose, administer the medication as soon as you remember. However, ensure that you consult your veterinarian if more than a month has passed since the last dose. It’s vital to maintain consistent monthly protection.

5. Are there any potential side effects?

While adverse reactions are rare, some dogs might experience digestive issues like vomiting or diarrhea. On rare occasions, neurological effects such as lethargy, tremors, or seizures might occur. If any unusual symptoms manifest, contact your vet immediately.

6. Is Heartgard Plus effective against all types of worms in dogs?

Heartgard Plus specifically targets heartworms, roundworms, and hookworms. However, it does not protect against tapeworms, whipworms, or other parasites. It’s essential to discuss comprehensive parasite prevention with your veterinarian.

7. Do I need a prescription for Heartgard Plus 26-50?

Yes, Heartgard Plus is a prescription medication. Your veterinarian will usually require an annual heartworm test before prescribing it. This ensures that your dog isn’t already infected, as administering preventatives to an infected dog can have adverse effects.

8. How long after administering Heartgard Plus can my dog eat?

There’s no need to wait! Your dog can eat before or after taking Heartgard Plus without any issues.

9. If my dog weighs more than 50 pounds, can I combine doses?

Always consult your veterinarian before changing or combining doses. While Heartgard Plus has a high safety margin, it’s essential to ensure that your pet receives the correct dosage based on their exact weight and health condition.

10. Can Heartgard Plus be used for cats?

Heartgard does have a formulation specifically for cats. If you’re considering heartworm prevention for your feline friend, ask your vet about Heartgard for Cats.

11. Can pregnant or breeding dogs use Heartgard Plus?

Heartgard Plus has been shown to be safe for pregnant, breeding, and lactating dogs. Nevertheless, before starting any medication or changing doses, it’s pivotal to consult with your veterinarian to address specific needs and concerns.

12. Does Heartgard Plus offer protection against fleas and ticks?

While Heartgard Plus offers robust protection against heartworms, roundworms, and hookworms, it does not protect against fleas or ticks. If you’re looking for comprehensive parasite protection, discuss additional or combination treatments with your vet.

13. How is Heartgard Plus metabolized in a dog’s system?

Ivermectin and Pyrantel, the active ingredients in Heartgard Plus, are primarily metabolized in the liver. Following metabolism, they’re excreted mainly through feces, with a smaller amount being removed through urine.

14. Is Heartgard Plus suitable for all breeds?

Heartgard Plus is suitable for most dog breeds. However, certain breeds like Collies and other herding dogs may be more sensitive to Ivermectin. It’s crucial to have a discussion with your veterinarian about breed-specific sensitivities.

15. What happens if Heartgard Plus is ingested by humans?

If a person accidentally ingests Heartgard Plus, they should seek immediate medical attention. Keep the packaging so that medical professionals can understand the ingested compounds.

16. How should I store Heartgard Plus chews?

Store Heartgard Plus chews at room temperature, away from moisture and direct sunlight. It’s equally vital to keep them out of reach of children and pets to prevent accidental ingestion.

17. Does Heartgard Plus interact with other medications?

There haven’t been widespread reports of Heartgard Plus interacting adversely with other common canine medications. Still, always inform your vet about any other drugs, supplements, or treatments your dog might be receiving.

18. Can older dogs start on Heartgard Plus?

Absolutely. Dogs of any age can benefit from the protective qualities of Heartgard Plus, as long as they don’t already have a heartworm infection. An initial test is recommended before starting elderly dogs on this preventative.

19. Does Heartgard Plus have an expiry date?

Yes, like all medications, Heartgard Plus does have an expiry date. It’s vital to check this date before administering to ensure the drug’s efficacy. Expired medications might not offer the protection your pet needs.

20. Can I give Heartgard Plus to my dog if traveling to a different climate or region?

Heartworm prevalence can vary by region. If you’re traveling or relocating, especially to warmer or more humid areas, it’s vital to maintain consistent heartworm prevention. However, consult with a local vet about any region-specific parasite concerns.

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