K9 Advantix II

K9 Advantix II is a popular flea and tick spot treatment for dogs that has received mixed reviews from pet owners. Let’s take a look at what some people have to say about this product.

K9 Advantix II Reviews


Many pet owners report that K9 Advantix II is effective at controlling fleas, ticks, lice, mites, and mosquitoes. Some even claim that it works better than other leading brands, such as Frontline Plus. However, there are also reports of the product being ineffective, particularly in areas with heavy infestations.


The safety of K9 Advantix II is a concern for some pet owners, as there have been reports of adverse reactions in dogs, ranging from mild skin irritation to more serious symptoms such as seizures and even death. However, it’s important to note that adverse reactions are relatively rare, and K9 Advantix II is generally considered safe when used as directed.


Many pet owners find K9 Advantix II easy to apply, with no mess or dripping. The tube of medication is easy to pierce, and the ointment itself is easy to spread on the dog’s skin. However, some pet owners have reported difficulty in applying the product, particularly with squirmy dogs.


K9 Advantix II is generally more expensive than other flea and tick treatments, which can be a drawback for some pet owners. However, many feel that the product is worth the extra cost for its effectiveness.

Overall, K9 Advantix II is a popular flea and tick treatment for dogs that has received both positive and negative reviews. While it’s generally considered safe and effective, it’s important to consult with your veterinarian before using any new product on your pet.

FAQs about K9 Advantix II

If you’re a dog owner looking for an effective flea and tick control product, you might have come across K9 Advantix II. This topical medication is popular among pet owners, but it’s natural to have some questions before using it on your furry friend. Here are some frequently asked questions about K9 Advantix II:

What is K9 Advantix II, and how does it work?

K9 Advantix II is a topical medication that helps prevent and control fleas, ticks, mosquitoes, and lice on dogs. The active ingredients in the product are Imidacloprid, Permethrin, and Pyriproxyfen. Imidacloprid and Permethrin work together to kill fleas and ticks, while Pyriproxyfen is an insect growth regulator that prevents the development of flea eggs and larvae.

Is K9 Advantix II safe for dogs?

When used according to the instructions on the packaging, K9 Advantix II is generally safe for dogs. However, it’s important to choose the correct dosage based on your dog’s weight, and to avoid using the product on puppies younger than 7 weeks old. It’s also essential to follow the instructions carefully and not to use the product on other pets or humans.

How do I apply K9 Advantix II to my dog?

To apply K9 Advantix II, part the fur on the back of your dog’s neck and apply the entire contents of the tube directly to the skin. Avoid applying the product near your dog’s eyes or mouth, and make sure your dog doesn’t lick or ingest the product. The medication will spread across your dog’s skin and coat, providing long-lasting protection against fleas and ticks.

How long does K9 Advantix II last?

K9 Advantix II provides protection against fleas and ticks for up to four weeks. After this time, you’ll need to reapply the medication to ensure continuous protection. However, keep in mind that the effectiveness of the product can vary depending on your dog’s size, health, and exposure to fleas and ticks.

Are there any side effects of K9 Advantix II?

While K9 Advantix II is generally safe for dogs, some dogs may experience side effects after using the product. The most common side effects include skin irritation, itching, and redness at the application site. Other side effects can include vomiting, diarrhea, and lethargy. If you notice any unusual symptoms after using K9 Advantix II on your dog, contact your veterinarian immediately.

Can I use K9 Advantix II on my cat?

No, K9 Advantix II is specifically designed for use on dogs and should not be used on cats. Using the product on cats can cause severe side effects and even death. If you have cats in your household, make sure to keep them away from your dog after applying K9 Advantix II.

Is K9 Advantix II waterproof?

Yes, K9 Advantix II is waterproof. It will continue to provide protection against fleas and ticks even if your dog gets wet or goes swimming.

Can K9 Advantix II be used on puppies?

K9 Advantix II is safe for puppies as young as seven weeks old and weighing over 3 pounds. However, it’s important to check with your veterinarian before using any flea and tick medication on your puppy.

Is K9 Advantix II safe for humans?

K9 Advantix II is designed to be safe for dogs and should not be harmful to humans. However, it’s important to wash your hands thoroughly after applying the treatment to your dog to avoid any accidental ingestion.

Can K9 Advantix II be used with other medications?

It’s always a good idea to consult with your veterinarian before using any flea and tick medication in combination with other medications. However, K9 Advantix II is generally safe to use with other medications, including heartworm preventatives.

What should I do if my dog experiences side effects from K9 Advantix II?

If your dog experiences any adverse reactions to K9 Advantix II, such as vomiting, diarrhea, or lethargy, you should contact your veterinarian immediately. In some cases, you may need to discontinue the use of the product and seek alternative treatments.

How soon after application can I bathe my dog?

It is recommended to wait at least 24 hours after application before bathing your dog. This allows the treatment to fully absorb into your dog’s skin and provide maximum protection against fleas and ticks.

Can I use K9 Advantix II on a pregnant or nursing dog?

It is recommended to consult with your veterinarian before using K9 Advantix II on a pregnant or nursing dog.

Can K9 Advantix II cause skin irritation in dogs?

It’s possible for dogs to experience skin irritation after using K9 Advantix II. However, it’s important to follow the product’s instructions carefully and apply the product to the back of the dog’s neck, where it cannot be licked or rubbed off. If your dog experiences skin irritation or other adverse reactions after using K9 Advantix II, contact your veterinarian.

Can K9 Advantix II prevent heartworm?

K9 Advantix II does not prevent heartworm, but it does kill mosquitoes that can transmit heartworm larvae to dogs. It’s important to use a separate heartworm prevention medication as recommended by your veterinarian.


Hannah Elizabeth is an English animal behavior author, having written for several online publications. With a degree in Animal Behaviour and over a decade of practical animal husbandry experience, Hannah's articles cover everything from pet care to wildlife conservation. When she isn't creating content for blog posts, Hannah enjoys long walks with her Rottweiler cross Senna, reading fantasy novels and breeding aquarium shrimp.

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