Benadryl and Melatonin: Can Dogs Take Melatonin and Benadryl Together?

This article will help you find out if Benadryl and Melatonin are safe to use together.

Benadryl and Melatonin together for dogs

Can I give my dog Benadryl and Melatonin together?

Yes, you can give your dog Melatonin and Benadryl in small doses.

NOTE: Always consult with your veterinarian before giving your dog over-the-counter medications or natural remedies.

Can Benadryl help dogs sleep?

Many dog owners wonder if they can give their dogs Benadryl to help with sleep as the medication is known to cause drowsiness. This is not a good idea as giving Benadryl on a regular basis can lead to long-term health problems for your dog. It also does not treat the cause of your dog’s insomnia.

You can give your dog Benadryl temporarily, but never on a regular basis. A safe dosage as a one-off or for a couple of days is 2 mg per kg of body weight or 1 mg per pound. Doses should be given at least 8 hours apart.

Benadryl should never be given to pregnant dogs or those suffering from heart failure, seizures, lung disease, or high blood pressure.

A better solution for your dog’s insomnia is to find the cause of his restless sleep and fix that. It could be due to an illness or injury, allergies, lack of exercise, or separation anxiety. Treating the cause will stop the restless sleep and you will not need to give your dog any kind of sedative.

How much Melatonin can I give my dog?

Melatonin tablets are designed to dissolve quickly in the dog’s mouth. They come in small (1 mg), medium (3 mg), and large (5 mg) doses.

Most veterinarians recommend giving dogs melatonin no more than 3 to 5 times a week, depending on the severity of the sleep disorder. The dosage should be based on the size of your dog, as some dogs have more sensitive systems than others.

What are the side effects of Melatonin for dogs?

The following side effects have been reported in dogs taking the drug melatonin: changes in fertility, gastric upset and stomach cramps, increased heart rate, itching, and confusion.

What is a natural sedative for a dog?

There are all kinds of products on the market that are designed to help calm dogs. These are called calming aids. Natural sedatives for dogs usually combine calming herbs, flower extracts, pheromones, and essential oils to help calm your dog.

Does Benadryl help dogs with mast cell tumors?

When a substance enters the dog’s body that they are allergic to, the body secretes histamines. This causes the typical symptoms of an allergic reaction such as hives and a runny nose. Benadryl contains diphenhydramine which is an antihistamine used to treat mild allergic reactions.

Mast cell tumors are a mass of white blood cells which also secrete histamine and can cause the symptoms of an allergic reaction. Benadryl can be used in low doses over a short period to treat skin irritation and sore eyes.

There are specific treatments for mast cell tumors that are far more effective and will treat the tumors themselves, not just the symptoms they cause.

Conclusion of Benadryl and Melatonin together for dogs

Melatonin and Benadryl together can be safe for dogs, but it is only recommended for short-term use. The side effects of melatonin are generally mild, but when used with Benadryl, the sedative effects of Benadryl may be enhanced. This means that your dog may be more sedated than expected during this time.

While these drugs may help some dogs, they may not be right for every pet. It may take several trials to find what works best for your dog. In addition, many dogs will benefit from a holistic approach that includes behavior modification and environmental changes along with medication.

At the end of the day, we all want our dogs to be as comfortable and happy as possible. We also want to keep them safe and healthy. If you decide that Melatonin and Benadryl is the best option for your dog, make sure you are observing the proper dosage.

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Hannah Elizabeth is an English animal behavior author, having written for several online publications. With a degree in Animal Behaviour and over a decade of practical animal husbandry experience, Hannah's articles cover everything from pet care to wildlife conservation. When she isn't creating content for blog posts, Hannah enjoys long walks with her Rottweiler cross Senna, reading fantasy novels and breeding aquarium shrimp.

2 Responses

  1. How much melatonin can I give my 19lb dog. She gets very car sick and I am driving to Illinois from Arizona with her. How much Benadryl and melatonin can I give at the same time. I gave her 1 mg of melatonin but it didn’t seem to help. Neither did 15mg of Benadryl. Do I give her 2 mg of melatonin and 18 of Benadryl? I don’t want to harm her for this trip but I can’t drive and make sure she doesn’t like all over my car at the same time.

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