6 Natural Alternative to Trazodone for Dogs

Trazodone may not be the best option for every dog and there are several alternatives that may be effective in managing these issues.

1. Melatonin


  • Melatonin is a naturally occurring hormone that is produced by the pineal gland in the brain. This means that it is generally considered safe for use in dogs.
  • Melatonin can be used to help dogs with anxiety, stress, and insomnia. It works by regulating the body’s natural sleep-wake cycle and promoting relaxation.
  • Melatonin is easily available over the counter and can be purchased in capsule form or as a liquid. It is also relatively inexpensive.
  • Some studies have shown that melatonin can be effective at reducing anxiety in dogs, particularly when used in combination with other natural remedies such as chamomile and valerian root.


  • Melatonin may not be effective for all dogs, and some dogs may not respond well to it.
  • It is important to start with a low dosage and gradually increase it to avoid side effects such as lethargy and disorientation.
  • Melatonin can interact with certain medications, so it is important to consult with a veterinarian before starting your dog on a melatonin supplement.
  • Some dogs may develop a tolerance to melatonin over time, making it less effective as a long-term treatment.

2. L-theanine


  • L-theanine is a natural amino acid that is found in green tea and has been shown to have a calming effect on the brain. This can help to reduce anxiety and improve sleep in dogs.
  • Unlike many prescription medications, L-theanine is generally well-tolerated and has few side effects. This makes it a safer choice for dogs with sensitive stomachs or other health issues.
  • L-theanine has been shown to be effective in reducing anxiety and improving sleep in humans, so it is likely to have similar effects in dogs.


  • L-theanine is not as widely available as prescription medications, so it may be more difficult to find and purchase.
  • L-theanine may not be as effective in severe cases of anxiety or insomnia. If your dog is experiencing severe symptoms, it is important to consult with a veterinarian before trying any natural alternatives.
  • L-theanine has not been extensively studied in dogs, so there is limited information available on its effectiveness and dosage. It is important to carefully follow the dosage instructions provided by your veterinarian or a trusted source.

3. Valerian root


  • Valerian root has been used for centuries as a natural sedative and has been shown to be effective in reducing anxiety and promoting relaxation in humans and animals.
  • It is a safe and natural alternative to pharmaceutical drugs, with minimal side effects.
  • Valerian root is easily accessible and can be purchased at most health food stores or online.


  • Valerian root may not be as effective as trazodone in managing severe anxiety or aggression in dogs.
  • It may take longer to see the effects of valerian root compared to pharmaceutical drugs.
  • Some dogs may not respond well to valerian root and may require a different natural alternative or a prescription medication.

4. Bach Flower Remedies


  • Bach Flower Remedies are made from the essence of flowers and are completely safe for dogs to take. They do not have any side effects and can be used in conjunction with other medications.
  • Bach Flower Remedies are chosen based on the individual dog’s specific emotional and behavioral needs. This means that each dog can receive a unique and customized treatment plan.
  • Bach Flower Remedies aim to address the root cause of the issue rather than just masking symptoms. This holistic approach can be more effective in the long term.


  • While Bach Flower Remedies have been used for decades, there is limited scientific evidence supporting their effectiveness.
  • Some dogs may not respond to Bach Flower Remedies, or may only experience a mild improvement in their symptoms.
  • Bach Flower Remedies are prescribed by trained practitioners who understand how to choose the correct remedies for each individual dog. This means that pet owners cannot simply purchase and administer them on their own.

5. Pheromone therapy


  • Pheromones are naturally occurring chemicals that dogs release to communicate with each other. They can have a calming effect on dogs, which can be helpful for those with anxiety or stress.
  • Pheromone therapy is non-invasive and can be administered through a collar, spray, or diffuser.
  • It has few side effects, making it a safer option compared to pharmaceutical medications.
  • Pheromone therapy can be used in conjunction with other natural remedies, such as herbal supplements or behavior modification techniques.


  • Pheromone therapy may not work for all dogs, and its effectiveness can vary from dog to dog.
  • It may not provide the same level of relief as pharmaceutical medications, so it may not be suitable for severe cases of anxiety or stress.
  • It can be expensive, depending on the type of pheromone therapy used.
  • Pheromone therapy may not be as effective in noisy or crowded environments.

6. Hemp-based products


  • Hemp-based products are derived from the cannabis plant, but do not contain THC, the psychoactive compound that causes a “high.” Therefore, they are safe for dogs to consume without any psychoactive effects.
  • Hemp-based products have been shown to have anti-inflammatory and analgesic properties, making them effective in reducing pain and inflammation in dogs.
  • They can be used to treat a variety of conditions, including anxiety, stress, and insomnia, making them a versatile alternative to trazodone.
  • Hemp-based products are widely available and can be found in various forms, such as oil, treats, and capsules, making them easy to administer to dogs.


  • Hemp-based products are not yet regulated by the FDA, so it is important to do thorough research and choose a reputable brand.
  • It is also important to consult with a veterinarian before starting any new supplement, as they can interact with other medications your dog may be taking.
  • Hemp-based products may not be as effective as traditional medications for certain conditions, such as severe anxiety or insomnia.
  • They can also be more expensive than traditional medications, so it is important to weigh the costs and benefits before deciding on a treatment option.

Conclusion of trazodone alternatives for dogs

Trazodone is a medication that is commonly used in dogs as an alternative treatment for anxiety and behavioral issues. However, there are other options available for treating these conditions in dogs. Some alternative options include:

  1. Fluoxetine: This medication is a selective serotonin reuptake inhibitor (SSRI) that is commonly used to treat anxiety and aggression in dogs.
  2. Sileo: This medication is a gel that is applied to the gums and is used to treat noise-associated anxiety in dogs.
  3. Clomicalm: This medication is a tricyclic antidepressant that is used to treat separation anxiety and other behavioral issues in dogs.
  4. Pheromone therapy: This type of therapy involves the use of synthetic pheromones that mimic the natural pheromones produced by dogs. These pheromones can help to reduce anxiety and promote a sense of calm in dogs.
  5. Behavioral modification training: This type of training is used to teach dogs new behaviors and ways of coping with their anxieties. It is important to work with a certified professional dog trainer or behaviorist.

These alternative options should be discussed with a veterinarian to determine the best course of treatment for your individual dog. Also, it’s worth mentioning that these alternatives may have side effects, and it is essential to consult the veterinarian before administering any treatment.


Hannah Elizabeth is an English animal behavior author, having written for several online publications. With a degree in Animal Behaviour and over a decade of practical animal husbandry experience, Hannah's articles cover everything from pet care to wildlife conservation. When she isn't creating content for blog posts, Hannah enjoys long walks with her Rottweiler cross Senna, reading fantasy novels and breeding aquarium shrimp.

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