Safe and Cost-Effective Alternatives to Nexgard

As dog owners, we are constantly on the lookout for the best products to keep our beloved pets healthy and safe. One popular product that many of us rely on is Nexgard, a chewable flea and tick preventative for dogs. However, not everyone can afford Nexgard or some dogs might not tolerate it well.

A Look at Nexgard

Nexgard is a well-regarded flea and tick preventative that falls into the isoxazoline class of drugs. This monthly oral treatment, containing the active ingredient Afoxolaner, kills fleas and ticks by overstimulating their nervous systems. While effective, some pet owners are seeking alternatives due to cost, availability, or their pet’s specific health needs.

Top Alternatives to Nexgard


One of the leading alternatives to Nexgard is Bravecto. Also belonging to the isoxazoline class, Bravecto offers protection from fleas and ticks for up to 12 weeks with a single dose, which can make it a more cost-effective choice for some pet owners.


Credelio is another excellent alternative that, like Nexgard and Bravecto, is an isoxazoline. Although it is comparable in price to Nexgard, some pet owners have found Credelio to be more effective for their dogs, especially those living in areas with a high flea and tick prevalence.


Simparica, another monthly chewable treatment, contains Sarolaner as the active ingredient. Its ability to begin killing fleas within three hours and ticks within eight hours can be appealing to owners with highly infested pets.

Simparica Trio

Simparica Trio combines the flea and tick protection of Simparica with heartworm disease prevention. This combination can be a cost-saving option for pet owners, reducing the need for multiple medications.


Vectra is a topical solution that offers broad-spectrum protection against fleas, ticks, mosquitoes, lice, and mites. This option could be ideal for those who prefer a topical solution over oral medication.

Considerations When Choosing an Alternative

When evaluating Nexgard alternatives, remember that every dog is unique, and what works best for one may not be the best for another. It’s important to consult with your vet before switching medications to ensure the alternative choice is safe for your dog and effective for your specific region and lifestyle.


While Nexgard is a reliable and effective solution for protecting dogs from fleas and ticks, it’s not the only option. Whether it’s Bravecto, Credelio, Simparica, Simparica Trio, or Vectra, there are several alternatives that can suit different needs and budgets. With proper research and veterinary guidance, you can find the right product to keep your furry friend healthy and pest-free.

FAQs: Exploring Alternatives to Nexgard

Q1: What is the difference between Nexgard and Bravecto?

Bravecto and Nexgard are both part of the isoxazoline class of medications and are effective in killing fleas and ticks. The primary difference lies in the duration of their efficacy. Nexgard requires monthly administration, while Bravecto provides up to 12 weeks of protection with a single dose. This can make Bravecto a more convenient option for pet owners who prefer less frequent dosing.

Q2: Can I switch from Nexgard to Credelio directly?

Yes, it is possible to switch directly from Nexgard to Credelio or any other flea and tick medication. However, it’s crucial to consult with your vet before making any changes to your pet’s medication regimen. They can provide guidance on the timing of the switch to ensure continuous protection and to minimize any potential side effects.

Q3: Is Simparica Trio a cost-effective alternative to Nexgard?

Simparica Trio can indeed be a more cost-effective alternative to Nexgard for some pet owners. It combines flea and tick prevention with heartworm disease prevention, eliminating the need for multiple medications and potentially reducing overall costs. However, the cost-effectiveness can vary based on factors like regional pricing and specific veterinary recommendations.

Q4: Can my dog have an adverse reaction when switching from Nexgard to another preventative?

As with any medication, there is always a possibility of adverse reactions when switching between different flea and tick preventatives. Common side effects can include vomiting, diarrhea, lethargy, loss of appetite, and skin reactions. It’s essential to monitor your dog closely after making a switch and report any concerns to your vet promptly.

Q5: Is Vectra a suitable alternative for dogs who can’t tolerate oral medications?

Vectra, a topical solution, can be a viable alternative for dogs who can’t tolerate oral medications like Nexgard. It offers broad-spectrum protection against fleas, ticks, mosquitoes, lice, and mites. However, some dogs may have skin reactions to topical solutions, so it’s important to monitor your dog after application and consult your vet if any concerns arise.

Q6: How can I ensure the alternative I choose to Nexgard is as effective?

The efficacy of a flea and tick preventative can be influenced by factors such as proper administration, the life cycle of the parasites, and environmental factors. Ensure to administer the medication as recommended by the manufacturer and consult your vet regularly. Monitor your pet for signs of infestation and consider combining medication with other preventative measures such as regular grooming and keeping your environment clean.

Q7: Are there natural alternatives to Nexgard?

While there are natural alternatives to Nexgard like certain essential oils, dietary supplements, and flea collars, their effectiveness can be highly variable and often is not backed by rigorous scientific research. They should not be relied upon as the sole method of flea and tick prevention, particularly in areas with high parasite prevalence. Always consult with your vet before incorporating natural alternatives into your pet’s parasite prevention strategy.

Q8: Can I use Nexgard and Heartgard together?

Yes, Nexgard and Heartgard can be used concurrently to offer your pet protection against a wide array of parasites. Nexgard provides effective control against fleas and ticks, while Heartgard is a preventive medication against heartworm disease. Always follow your veterinarian’s recommendations for parasite control to ensure your pet receives comprehensive protection.

Q9: How does Revolution compare as an alternative to Nexgard?

Revolution is a topical medication that is used to prevent heartworms and control fleas, ticks, and mites. Unlike Nexgard, which is an oral medication, Revolution is applied to the skin. While Nexgard is focused on controlling fleas and ticks, Revolution offers broader protection against multiple types of parasites. However, your pet’s specific needs and your vet’s advice should guide your choice.

Q10: Are there any non-prescription alternatives to Nexgard?

While there are non-prescription products available on the market that claim to prevent or treat flea and tick infestations, they may not be as effective or safe as prescription treatments. Non-prescription treatments can range from over-the-counter oral medications to topical sprays, shampoos, and collars. Always consult your vet before starting a new flea and tick preventative, whether it’s prescription or over-the-counter.

Q11: Why should I consider an alternative to Nexgard?

While Nexgard is a popular and effective choice for many dogs, every dog is unique and may have different needs or react differently to medications. Some dogs may experience side effects with Nexgard, or it may not be as effective for some dogs due to factors like regional parasite resistance. In such cases, exploring alternatives with your vet’s guidance can help ensure your dog gets the best possible protection.

Q12: Can I use Nexgard for my cat?

No, Nexgard is only approved for use in dogs. For cats, there are other products such as Bravecto for cats, Revolution, and Advantage II that are designed and approved for feline use. It’s crucial to never use a dog product on a cat, as it can lead to severe adverse reactions, including death.

Q13: Is there a cheaper generic version of Nexgard available?

There were no generic versions of Nexgard available. However, it’s always wise to discuss cost concerns with your vet. They may be aware of newer generic options or alternative medications that fit within your budget. Remember that cost should never be the only factor in choosing a flea and tick preventative; safety and efficacy are paramount.

Q14: How often should I give my dog Nexgard?

Nexgard is typically administered once a month to ensure constant protection against fleas and ticks. However, the exact dosage and frequency may vary depending on your pet’s weight, health status, and your vet’s recommendations. Always follow the directions given by your vet and on the product label.

Q15: Are there any side effects associated with Nexgard?

Yes, as with any medication, Nexgard can have potential side effects. Some dogs may experience vomiting, diarrhea, lack of appetite, or lethargy. Severe reactions such as seizures are rare but have been reported. If your dog exhibits any adverse reactions after taking Nexgard, contact your vet immediately.

Q16: Can puppies take Nexgard?

Nexgard is approved for use in dogs and puppies that are at least 8 weeks old and weigh at least 4 pounds. However, for puppies, it is essential to consult with your vet before starting any flea and tick preventative treatment to ensure it’s safe and appropriate for your pet’s age, size, and health condition.

Q17: Can pregnant or lactating dogs use Nexgard?

The safety of Nexgard has not been evaluated in breeding, pregnant, or lactating dogs. If your dog falls into any of these categories, it is crucial to consult with your vet before using Nexgard or any other flea and tick preventative treatment.

Q18: What should I do if I miss a dose of Nexgard?

If you miss giving your dog a dose of Nexgard, administer it as soon as you remember, and then continue on the monthly schedule. Do not double-dose to make up for the missed one. Keeping a consistent schedule is essential for maintaining protection against fleas and ticks.

Q19: Can I bathe my dog after administering Nexgard?

Yes, you can bathe your dog or let them swim after administering Nexgard. Since Nexgard is an oral medication, it’s not affected by bathing, swimming, or any other exposure to water.

Q20: How should I store Nexgard?

Nexgard should be stored at room temperature (between 68°F – 77°F, or 20°C – 25°C) in a safe place out of reach of children and pets. It should not be stored in the refrigerator or freezer. Always refer to the storage instructions provided on the package.

Leave a Reply

Your email address will not be published. Required fields are marked *

Back to Top