Does Cytopoint Cause Cancer in Dogs?

As a pet parent, the well-being of your furry friend is of utmost importance. One common concern is the potential link between Cytopoint injections and cancer in dogs. In this article, we’ll explore the safety of Cytopoint, its potential side effects, and what veterinarians have to say about its use in treating canine allergies.

Understanding Cytopoint

Cytopoint (lokivetmab) is a monoclonal antibody designed to target and neutralize interleukin-31 (IL-31), a protein involved in causing itchiness in dogs. It is primarily used to treat atopic dermatitis, a chronic skin condition caused by environmental allergens. Cytopoint offers relief from itching without the potential side effects of steroids and other immunosuppressive drugs.

Current Research and Veterinary Insights

Based on available research and expert opinions, there is no strong evidence to suggest that Cytopoint causes cancer in dogs. The primary risk factor for cancer in dogs is age, not the administration of Cytopoint injections.

Potential Side Effects of Cytopoint

While Cytopoint has been proven to be safe for most dogs, it’s essential to be aware of potential side effects. These can include:

Injection site reactions: Some dogs may experience a temporary discomfort or swelling at the injection site.

Fatigue: Some dogs may become tired or lethargic after receiving Cytopoint injections.

GI issues: In rare cases, dogs may experience gastrointestinal problems, such as vomiting or diarrhea, after Cytopoint administration.

It’s important to remember that these side effects are relatively rare, and most dogs tolerate Cytopoint injections well. If your dog experiences any of these symptoms, consult your veterinarian for further evaluation.

Comparing Cytopoint to Other Allergy Treatments


Apoquel (oclacitinib) is another popular medication used to treat canine allergies. Unlike Cytopoint, Apoquel is an oral medication that works by inhibiting the enzymes responsible for inflammation and itching. While there is no evidence to suggest that Apoquel causes cancer in dogs, some studies have indicated that it may accelerate preexisting cancers. This is why veterinarians may recommend against using Apoquel in dogs with a history of cancer.

Allergy Shots and Immunotherapy

Allergy shots or immunotherapy involve administering small doses of allergens to your dog over time, helping them develop a tolerance to the allergens. This treatment is more focused on addressing the root cause of the allergies rather than simply managing the symptoms. It is a longer-term solution but does not pose a risk of causing cancer.

How long does it take for Cytopoint to start working?

Cytopoint typically begins to relieve itching within 24 hours of administration. However, it may take up to a week for some dogs to experience significant improvement in their symptoms.

How long does the effect of Cytopoint last?

The duration of Cytopoint’s effects can vary between dogs. Generally, a single injection provides relief from itching for 4-8 weeks. Your veterinarian will monitor your dog’s response to the treatment and recommend a suitable schedule for follow-up injections.

Can Cytopoint be used alongside other allergy medications?

Yes, Cytopoint can be used in conjunction with other allergy medications such as antihistamines, corticosteroids, or topical treatments. However, it’s essential to consult your veterinarian before combining medications to ensure the safety and effectiveness of the treatment plan.

Are there any contraindications for using Cytopoint?

Cytopoint is not recommended for use in dogs with a history of hypersensitivity to lokivetmab or any of its components. Additionally, it is not intended for use in dogs less than 1 year of age or weighing less than 3 kg (6.6 lbs).

Can Cytopoint be used in pregnant or lactating dogs?

The safety of Cytopoint in pregnant or lactating dogs has not been thoroughly studied. Consult your veterinarian before using Cytopoint in pregnant or lactating dogs to discuss potential risks and benefits.

Is Cytopoint suitable for long-term use?

Cytopoint is considered safe for long-term use in dogs with atopic dermatitis. Regular monitoring by your veterinarian is essential to ensure the continued effectiveness and safety of the treatment.

How is Cytopoint administered?

Cytopoint is administered as a subcutaneous injection by a veterinarian. The dosage is determined based on your dog’s body weight, and the injection is typically given once every 4-8 weeks.

What should I do if my dog experiences side effects from Cytopoint?

If your dog experiences any side effects or adverse reactions after receiving a Cytopoint injection, contact your veterinarian immediately. They can assess the situation, provide appropriate care, and adjust the treatment plan if necessary.

Will Cytopoint cure my dog’s allergies?

Cytopoint is not a cure for allergies. It helps manage the symptoms of atopic dermatitis by targeting the protein responsible for causing itchiness. To address the root cause of allergies, your veterinarian may recommend additional treatments such as allergen-specific immunotherapy or dietary changes.

Can Cytopoint be used to treat other skin conditions in dogs?

Cytopoint is specifically designed to treat atopic dermatitis in dogs. While it may provide some relief for other skin conditions associated with itchiness, it’s essential to consult your veterinarian for a proper diagnosis and treatment plan tailored to your dog’s specific needs.

How much does a Cytopoint injection cost?

The cost of Cytopoint injections can vary depending on factors such as your dog’s weight, the frequency of injections, and your location. On average, the price can range from $75 to $200 per injection. It’s best to consult your veterinarian for an accurate estimate based on your dog’s specific needs.

Can Cytopoint be used for cats?

Cytopoint is specifically designed and approved for use in dogs. There is currently no data on the safety and effectiveness of Cytopoint in cats. If your cat is experiencing allergies or skin issues, consult your veterinarian for a proper diagnosis and appropriate treatment options.

What is the difference between Cytopoint and other monoclonal antibody treatments?

Cytopoint is a monoclonal antibody treatment specifically targeting the interleukin-31 (IL-31) protein responsible for itching in dogs with atopic dermatitis. Other monoclonal antibody treatments may target different proteins or pathways involved in various health conditions. The effectiveness and safety of each treatment depend on the specific target and the condition being treated.

Can my dog develop resistance to Cytopoint?

There is no evidence to suggest that dogs can develop resistance to Cytopoint. However, it is crucial to follow your veterinarian’s recommendations for treatment frequency and dosage to maintain its effectiveness.

Is it safe to give my dog vaccinations while they are on Cytopoint?

There is no known interaction between Cytopoint and routine vaccinations. However, it’s essential to discuss your dog’s vaccination schedule with your veterinarian, especially if they are receiving Cytopoint or other allergy treatments. Your veterinarian can provide guidance on the best course of action for your dog’s overall health.

How should I store Cytopoint?

Cytopoint should be stored in its original packaging under refrigerated conditions (2°C to 8°C or 36°F to 46°F) and protected from light. Do not freeze or shake the vial.

Can I give my dog Cytopoint injections at home?

Cytopoint injections should be administered by a veterinarian or a trained professional. It is not recommended for pet owners to administer Cytopoint injections at home.

Can Cytopoint cause weight gain in dogs?

Weight gain is not a known side effect of Cytopoint. If your dog is experiencing weight changes, it’s essential to consult your veterinarian to rule out other potential causes and adjust their diet or exercise routine as needed.

Are there any breed-specific risks associated with Cytopoint?

There are no known breed-specific risks associated with the use of Cytopoint. It has been demonstrated to be safe and effective in various dog breeds suffering from atopic dermatitis.

Can Cytopoint help with food allergies in dogs?

Cytopoint is designed to target and neutralize the IL-31 protein, which causes itchiness in dogs with atopic dermatitis. While it may provide some relief from itching related to food allergies, it does not address the underlying cause. For food allergies, it is essential to work with your veterinarian to identify and eliminate the allergen from your dog’s diet.

Leave a Reply

Your email address will not be published. Required fields are marked *

Back to Top