Will Galliprant Side Effects in Dogs Go Away? 🐕💊

Galliprant is a popular nonsteroidal anti-inflammatory drug (NSAID) used to manage pain and inflammation in dogs suffering from osteoarthritis. While it’s known for being effective with fewer side effects compared to traditional NSAIDs, many pet owners still wonder if the side effects they observe will go away over time. In this guide, we’ll address the most common side effects, how long they typically last, and what to watch out for to keep your dog comfortable and safe.

Key Takeaways:

  • What are the common side effects of Galliprant? 🤔 Vomiting, diarrhea, and loss of appetite are the most common.
  • Will the side effects go away over time? 🕰️ Mild side effects often improve after the first few doses.
  • When should I stop giving Galliprant? ⚠️ Severe symptoms like bloody stools or lethargy should prompt immediate consultation with your vet.
  • How can I minimize side effects? 🛡️ Giving Galliprant with food can help reduce gastrointestinal issues.

What Are the Most Common Side Effects of Galliprant? 🤔

Like any medication, Galliprant can cause side effects in some dogs. The most frequently reported issues are gastrointestinal (GI) symptoms, including:

  1. Vomiting
  2. Diarrhea
  3. Loss of appetite
  4. Soft stools

These symptoms are usually mild, and many dogs tolerate the medication well without experiencing severe issues. Some dogs may also exhibit lethargy or seem more tired than usual after starting the medication. It’s important to monitor your dog closely for any changes in their behavior or overall health while on Galliprant.

In rare cases, more serious side effects like bloody stools, jaundice (yellowing of the gums or skin), or excessive thirst may occur. These are signs of potentially severe reactions and require immediate veterinary attention.

Common Side EffectsWhat You May Notice
🤢 VomitingMild, occasional nausea or throwing up
🚽 DiarrheaSoft or loose stools, sometimes frequent
🍽️ Loss of appetiteRefusal to eat or disinterest in food
💤 LethargyUnusual tiredness or lack of energy

Will Galliprant Side Effects Go Away Over Time? 🕰️

In many cases, mild side effects like vomiting, diarrhea, or loss of appetite tend to lessen or go away after the first few doses as your dog’s body adjusts to the medication. Typically, within a week or two, dogs start to tolerate Galliprant better, and the GI issues subside.

However, if these side effects persist beyond the first couple of weeks or worsen, it’s important to contact your vet. Your dog’s system may not be adjusting to the medication as expected, and your vet may suggest a different dosage or an alternative pain management solution.

For dogs with more sensitive stomachs, giving Galliprant with food can help mitigate GI symptoms, making it easier on their digestive system. Hydration is also important, especially if diarrhea is present, to prevent dehydration.

Will Side Effects Go Away?Expected Duration
⏳ Usually improves after 1-2 weeksThe body adjusts over time
🍽️ Giving with food helpsCan reduce GI side effects
💧 Hydration is keyPrevents dehydration if diarrhea occurs

When Should I Be Concerned About Galliprant Side Effects? ⚠️

While mild side effects are often manageable and fade with time, there are certain symptoms that should be taken more seriously. If your dog experiences any of the following, it’s crucial to contact your vet immediately:

  1. Bloody stools or black, tarry stools – This can indicate internal bleeding, a more severe side effect of NSAIDs.
  2. Excessive vomiting or diarrhea – If these symptoms persist and your dog becomes weak or dehydrated, discontinue use and seek veterinary care.
  3. Lethargy or unresponsiveness – A sign that your dog’s system may not be tolerating the medication.
  4. Jaundice – Yellowing of the gums or skin, which could signal liver issues.

These symptoms may indicate a serious reaction to Galliprant, and your vet may decide to stop the medication and choose an alternative pain management plan. Regular blood tests to monitor liver and kidney function can help catch these issues early, especially in long-term use.

When to Contact Your VetSymptoms to Watch For
🩸 Bloody or black stoolsSign of possible internal bleeding
🤮 Persistent vomiting or severe diarrheaIndicates intolerance or potential toxicity
😴 Extreme lethargy or unresponsivenessCould signal a serious adverse reaction
🟡 Jaundice (yellow gums or skin)Possible liver issues

How Can I Minimize the Risk of Side Effects? 🛡️

While side effects from Galliprant can’t always be avoided, there are steps you can take to reduce the likelihood of your dog experiencing discomfort:

  1. Give Galliprant with food – Administering the medication with meals can help reduce the chances of stomach upset and make the drug easier to tolerate.
  2. Hydrate – Ensure your dog has constant access to fresh water, especially if they’re experiencing mild diarrhea or vomiting.
  3. Start with the lowest effective dose – Work with your vet to find the lowest dose that still provides pain relief. This can help minimize side effects while maintaining efficacy.
  4. Monitor your dog closely – Keep a journal of any side effects and share it with your vet during follow-up visits. This can help track how your dog is adjusting to the medication and whether adjustments need to be made.

By staying proactive and keeping an eye on your dog’s response to Galliprant, you can help ensure that any potential side effects are addressed quickly and effectively.

Ways to Minimize Side EffectsWhy It Helps
🍽️ Give with mealsReduces stomach upset and GI issues
💧 Keep your dog hydratedHelps prevent dehydration from diarrhea
🏷️ Use the lowest effective doseLimits the risk of adverse effects
📋 Track and report side effectsAllows for better management of symptoms

Final Thoughts: Will Galliprant Side Effects in Dogs Go Away? 🐾

While mild side effects of Galliprant such as vomiting, diarrhea, and lethargy are relatively common, they often improve over time as your dog adjusts to the medication. Most side effects fade after a week or two, especially if the medication is given with food. However, more serious symptoms like bloody stools or jaundice require immediate attention.

Always consult with your vet about the best ways to manage side effects, and don’t hesitate to reach out if you notice any concerning changes in your dog’s health. Galliprant can be a highly effective tool for managing pain and inflammation, but careful monitoring ensures your dog remains safe and comfortable.


Comment 1: “How long should I wait to see if the side effects of Galliprant improve?”

It’s common to notice mild side effects like vomiting, diarrhea, or a slight loss of appetite when your dog first starts taking Galliprant. In most cases, these symptoms should begin to improve within a week or two as your dog’s system adjusts to the medication. During this adjustment period, it’s important to monitor your dog closely. If the symptoms are mild and don’t interfere with their overall well-being, you can continue the medication but keep a close eye on their progress.

If after two weeks the side effects persist or worsen, it’s time to contact your vet. Continuing beyond this point without improvement could lead to unnecessary discomfort for your dog, and your vet may suggest adjusting the dose, adding supportive care, or switching medications entirely. In more sensitive dogs, the GI symptoms could be more severe, requiring a quicker intervention.

To help ease the adjustment, try administering Galliprant with food—this can often alleviate stomach upset and improve overall tolerance.

Wait Time for Side Effect ImprovementWhat You Should Watch For
🕒 1-2 weeksMild symptoms usually improve within this time
🍽️ Administer with foodHelps minimize gastrointestinal side effects
⚠️ Contact your vet after 2 weeksIf symptoms persist or worsen

Comment 2: “Can I give Galliprant with other medications like painkillers or supplements?”

Galliprant is often prescribed alongside other medications, but it’s essential to be cautious, especially when combining it with other NSAIDs (like Rimadyl) or corticosteroids (like prednisone). These combinations can increase the risk of serious side effects, including gastrointestinal ulcers, bleeding, or kidney damage. As a result, Galliprant should never be given with other NSAIDs or steroids, as the combined effects on your dog’s body can be harmful.

However, many dogs do well with Galliprant in conjunction with supplements such as glucosamine, chondroitin, omega-3 fatty acids, or joint-support products. These can enhance the benefits of Galliprant by addressing joint inflammation and cartilage health, while the medication focuses on pain management. If your dog is on multiple medications, always discuss the full list with your vet to ensure that all drugs and supplements are safe to use together.

Medications Safe to Combine with GalliprantWhy It’s Important
❌ Avoid combining with NSAIDs or steroidsIncreases risk of serious side effects
🦴 Joint supplements (glucosamine, chondroitin)Supports joint health alongside Galliprant
🧑‍⚕️ Always consult your vetEnsures safe combination of medications

Comment 3: “How can I tell if my dog is allergic to Galliprant?”

An allergic reaction to Galliprant, while rare, can occur. The signs of an allergy can vary from mild to severe and should be monitored carefully. Symptoms of an allergic reaction might include:

  • Hives or red patches on the skin
  • Swelling of the face, lips, or paws
  • Difficulty breathing or wheezing
  • Itching and excessive scratching
  • Vomiting and diarrhea that appear suddenly and seem severe

If you notice any of these symptoms, especially if your dog has trouble breathing or is showing signs of facial swelling, this could be a sign of a serious allergic reaction known as anaphylaxis, which requires immediate veterinary care. Even if the symptoms are mild, it’s important to stop the medication and contact your vet to discuss the next steps.

Your vet may decide to discontinue Galliprant and choose an alternative medication or may prescribe antihistamines or corticosteroids to help control the allergic response, depending on the severity of the reaction.

Signs of an Allergic Reaction to GalliprantWhat to Do
🔴 Hives, swelling of the face or lipsDiscontinue medication and contact your vet
🐾 Excessive itching or scratchingCould indicate a developing allergy
🚨 Difficulty breathingEmergency, immediate veterinary attention required

Comment 4: “Should I give Galliprant on an empty stomach or with food?”

While Galliprant can technically be given with or without food, many vets recommend administering it with food, particularly if your dog has shown signs of sensitive digestion or has experienced mild side effects like vomiting or diarrhea. Giving Galliprant with a meal can help reduce the risk of stomach upset and make the medication easier on your dog’s gastrointestinal system.

For dogs that tolerate it well, giving Galliprant on an empty stomach may not cause any issues, but if you’re noticing signs of discomfort after giving the medication, adding it to your dog’s breakfast or dinner could alleviate these symptoms. In general, feeding your dog before giving Galliprant helps ensure better tolerance and smoother digestion of the medication.

Giving Galliprant with FoodWhy It Helps
🍽️ Reduces risk of stomach upsetHelps prevent nausea, vomiting, and diarrhea
🐾 Easier on sensitive stomachsParticularly useful for dogs prone to digestive issues
🕒 Give with meals for better toleranceReduces GI irritation and supports overall comfort

Comment 5: “Is it normal for my dog to be more tired than usual on Galliprant?”

Lethargy is a potential side effect of Galliprant, though it is usually mild and temporary. Some dogs may become more tired or sluggish as their body adjusts to the medication. This side effect often improves as your dog gets used to the drug over the course of one to two weeks. If your dog’s lethargy is mild and they are still eating, drinking, and interacting normally, there’s generally no cause for concern.

However, if the lethargy is extreme, or if it’s accompanied by other worrisome symptoms like vomiting, diarrhea, or a loss of coordination, it could signal a more serious reaction, and you should contact your vet immediately. Galliprant is designed to manage pain, so while a slight decrease in activity is normal, your dog should still be able to enjoy walks and engage with you.

Lethargy as a Side EffectWhat’s Normal vs. Concerning
😴 Mild lethargy is common in the first few daysYour dog may seem more tired than usual
🕒 Should improve after 1-2 weeksWatch for improvement over time
🚨 Extreme lethargy with other symptomsMay indicate a more serious issue, contact vet

Comment 6: “Can Galliprant cause long-term side effects?”

While Galliprant is generally considered safer for long-term use compared to traditional NSAIDs, especially regarding its kidney and liver impact, there is still a potential for long-term side effects. Regular use of any medication requires monitoring, and over time, you’ll want to ensure that Galliprant isn’t causing any unexpected complications.

Some dogs may develop gastrointestinal issues over prolonged use, such as chronic diarrhea or vomiting, while others may experience kidney or liver strain in rare cases. To prevent these issues, your vet will likely recommend periodic blood tests to monitor your dog’s liver and kidney function, especially if Galliprant is being used long-term. These tests can catch any early signs of organ stress and allow for adjustments in treatment if necessary.

It’s also important to regularly assess your dog’s overall well-being—if they develop unexplained weight loss, changes in thirst, or persistent lethargy, these could be signs of underlying problems related to the medication. Galliprant has shown a lower risk of serious side effects than many other NSAIDs, but keeping up with routine vet visits ensures your dog stays healthy.

Long-Term Use ConsiderationsHow to Manage Risks
🩸 Regular blood tests to monitor organ functionEnsures early detection of potential liver or kidney issues
🍽️ Watch for chronic GI issues (diarrhea, vomiting)May signal the need for an alternative medication
🏥 Periodic vet check-upsCritical for safe long-term use

Comment 7: “What should I do if my dog misses a dose of Galliprant?”

If your dog misses a dose of Galliprant, don’t panic. Simply give the missed dose as soon as you remember, unless it’s close to the time for the next scheduled dose. In that case, skip the missed dose and continue with the regular dosing schedule. Never double up on doses to make up for the one you missed, as this could increase the risk of side effects, including gastrointestinal issues or potential toxicity.

If your dog is using Galliprant for chronic conditions like arthritis, maintaining a consistent dosing schedule is important to keep their pain under control. Missing an occasional dose is not likely to cause a major problem, but if you notice your dog becoming more uncomfortable or stiff, this could be a sign that their pain is returning due to the missed medication. Try to get back on schedule as soon as possible to ensure they’re receiving continuous pain relief.

What to Do If You Miss a DoseWhy It’s Important
⏳ Give as soon as you remember, unless it’s close to the next dosePrevents inconsistent pain relief
🚫 Don’t double up on dosesAvoids increasing the risk of side effects
🐕 Monitor for signs of discomfortEnsure your dog remains comfortable between doses
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