🐾 What Is the New Injection for Dogs with Arthritis?

Published on: December 12, 2024March 24, 2025Author: Bestie Paws

Arthritis in dogs, particularly osteoarthritis, is a common condition that affects their mobility and quality of life. Recent advancements in veterinary medicine have introduced injectable treatments designed to manage pain and improve mobility effectively. Here’s everything you need to know about the new injections for dogs with arthritis.

Key Takeaways: Quick Answers to Common Questions

What’s the newest injection for arthritis? 🩺 Monoclonal antibody therapies like Librela (Bedinvetmab).
How does it work? ✅ Targets nerve growth factor (NGF) to reduce pain.
What other options are there? 🐾 Synovetin OA, Adequan, and Spryng offer alternative injectables.
Is it safe for all dogs? 🩺 Yes, but always consult your vet for individual suitability.
How long does relief last? ⏳ Depending on the injection, relief can last from one month to over a year.

1. What Is Librela (Bedinvetmab)? 🩺 The Game-Changer

Librela, containing the active ingredient bedinvetmab, is a monoclonal antibody therapy approved for managing osteoarthritis pain in dogs.

How It Works: Librela blocks nerve growth factor (NGF), a protein involved in transmitting pain signals in arthritis.
Frequency: Administered as a monthly subcutaneous injection.
Effectiveness: Provides consistent pain relief, allowing dogs to regain mobility and improve their quality of life.

💡 Tip: Librela is ideal for dogs with moderate to severe arthritis that haven’t responded well to oral medications.

2. What Is Synovetin OA? 🌟 A Long-Lasting Option

Synovetin OA offers a cutting-edge approach for dogs with elbow osteoarthritis through an intra-articular injection.

How It Works: Delivers Tin-117m, a radioactive isotope, directly into the joint to reduce inflammation by deactivating inflammatory macrophages.
Duration: Pain relief lasts up to one year after a single injection.
Best For: Dogs with localized joint issues, particularly in the elbow.

💡 Tip: Synovetin OA is especially effective for dogs experiencing limited response to other arthritis treatments.

3. What Is Adequan® Canine? 🐾 The Cartilage Protector

Adequan is a trusted option for managing non-infectious arthritis through intramuscular injections.

How It Works: Contains polysulfated glycosaminoglycans (PSGAGs) that support cartilage repair and reduce joint inflammation.
Schedule: Typically administered twice a week for four weeks.
Benefits: Improves joint lubrication and slows down cartilage degeneration.

💡 Tip: Combine Adequan with weight management and physical therapy for optimal results.

4. What Is Spryng with OsteoCushion Technology? 💧 A Natural Cushion

Spryng is an innovative injectable designed to replicate the cushioning effect of healthy cartilage.

How It Works: Uses collagen-elastin hydrogel microparticles to mimic natural cartilage, reducing joint stress and pain.
Applications: Ideal for dogs with advanced arthritis or cartilage loss.
Duration: Provides long-lasting joint support, but periodic follow-ups may be required.

💡 Tip: Spryng is suitable for dogs of all sizes and breeds with severe joint issues.

5. What Are the Key Differences Between These Injections?

Treatment	How It Works	Duration	Best For	💡 Tip
Librela	Blocks pain signals via NGF inhibition	1 month per injection	Dogs with moderate-to-severe arthritis	Monthly maintenance required.
Synovetin OA	Reduces inflammation with Tin-117m	Up to 1 year	Localized joint issues, especially elbows	Ideal for long-term relief.
Adequan	Protects cartilage and reduces swelling	4 weeks per course	Generalized arthritis or early-stage OA	Combine with lifestyle changes.
Spryng	Mimics cartilage cushioning	Long-lasting	Advanced arthritis or cartilage loss	Suitable for severe cases.

6. Are These Injections Safe for All Dogs? 🩺

While these treatments are generally safe, certain factors must be considered:

Age and Health: Older dogs or those with underlying health issues may require additional screening.
Concurrent Medications: Inform your vet about any medications your dog is currently taking to avoid interactions.
Allergy History: Although rare, allergic reactions to injection components can occur.

💡 Tip: Always consult your veterinarian to determine the most appropriate treatment for your dog’s specific condition.

7. How Do These Injections Compare to Oral Medications? 💊

Injectable treatments offer several advantages over oral medications:

Targeted Action: Many injections work directly within the joint or on pain pathways, providing more focused relief.
Fewer Side Effects: Unlike NSAIDs, injections often avoid gastrointestinal or kidney-related side effects.
Convenience: Long-lasting injections reduce the need for daily dosing, making them easier for owners to manage.

Discover 🐶 How to Fly with a Large Dog

💡 Tip: For dogs that struggle with pills or have sensitive stomachs, injectable therapies can be a game-changer.

8. What Should I Expect After an Injection? 🐕

Immediate Effects: Pain relief may be noticeable within a few days, depending on the treatment.
Monitoring: Watch for side effects like swelling at the injection site or unusual behavior.
Follow-Up: Schedule regular check-ups to assess the treatment’s effectiveness and plan future doses.

💡 Tip: Keep a journal of your dog’s mobility and comfort levels post-treatment to share with your vet.

FAQs 🐾✨

Comment 1: “How does Librela differ from traditional arthritis treatments like NSAIDs?”

Librela offers a unique mechanism of action compared to nonsteroidal anti-inflammatory drugs (NSAIDs), targeting arthritis pain more precisely.

Mechanism: Librela uses monoclonal antibodies to block nerve growth factor (NGF), a key player in transmitting pain signals. NSAIDs, on the other hand, inhibit cyclooxygenase (COX) enzymes, which reduce inflammation but may have broader systemic effects.
Safety Profile: Librela avoids common NSAID side effects like gastrointestinal irritation, kidney strain, or liver stress, making it safer for long-term use.
Targeted Relief: By focusing solely on pain pathways, Librela addresses chronic discomfort without compromising other physiological processes.

💡 Tip: For dogs that cannot tolerate NSAIDs, Librela provides a safer, equally effective alternative for managing arthritis pain.

Comment 2: “Is Synovetin OA suitable for all types of arthritis?”

Synovetin OA is highly effective for specific cases but isn’t a universal solution for all arthritis types.

Targeted Use: This injection is particularly beneficial for localized joint arthritis, such as elbow osteoarthritis, where inflammation is concentrated.
Long-Term Relief: A single injection can offer up to 12 months of pain relief, ideal for dogs requiring infrequent treatments.
Limitations: It may not be the best choice for dogs with widespread arthritis affecting multiple joints, as it targets one specific joint at a time.

💡 Tip: Synovetin OA works best as part of a multimodal treatment plan that includes lifestyle adjustments and physical therapy.

Comment 3: “Can injections like Adequan reverse arthritis damage?”

Adequan cannot reverse arthritis but can slow its progression and alleviate symptoms.

Cartilage Support: Adequan helps maintain cartilage by stimulating its repair and preventing further breakdown, preserving joint function.
Inflammation Reduction: It reduces joint inflammation, which lessens pain and improves mobility.
Degeneration Management: While it doesn’t regenerate damaged cartilage, Adequan helps delay the progression of arthritis, enhancing quality of life.

💡 Tip: Combine Adequan with weight management and low-impact exercises to maximize its benefits.

Comment 4: “What should I monitor after my dog receives an arthritis injection?”

Post-injection care involves closely observing your dog for signs of improvement or adverse reactions.

Mobility Changes: Track improvements in walking, climbing stairs, or playing, as these indicate the injection’s effectiveness.
Injection Site Reactions: Check for swelling, redness, or tenderness around the injection area, which typically resolve within a day.
Behavioral Shifts: Increased energy and decreased discomfort suggest successful pain management. Conversely, lethargy or agitation may indicate a need for veterinary follow-up.

💡 Tip: Keep a log of your dog’s activity levels and any changes to share with your vet during follow-ups.

Comment 5: “Are these injections covered by pet insurance?”

Coverage depends on your pet insurance provider and the policy you hold.

Prescription Medications: Treatments like Librela and Adequan are often covered under plans that include prescription medications.
Specialized Procedures: Synovetin OA may fall under surgical or advanced therapeutic coverage due to its intra-articular administration.
Pre-Existing Conditions: Arthritis classified as a pre-existing condition may not be covered, so early enrollment in insurance is crucial.

💡 Tip: Contact your insurance provider beforehand to confirm coverage and inquire about reimbursement for these treatments.

Comment 6: “Can injections be combined with other arthritis therapies?”

Yes, injections can be effectively combined with other treatments to provide comprehensive arthritis management.

Medications: Injections like Adequan or Librela pair well with oral joint supplements or occasional NSAIDs for flare-ups.
Physical Therapy: Low-impact exercises and hydrotherapy improve joint mobility and complement injectable treatments.
Diet and Weight Control: Maintaining an optimal weight reduces stress on joints, enhancing the effectiveness of injections.

Discover What’s Better Than Apoquel for Dogs? 🐾

💡 Tip: Always coordinate treatment plans with your veterinarian to ensure compatibility and avoid overloading your dog’s system.

Comment 7: “Are there side effects of arthritis injections?”

Side effects of arthritis injections are rare but can occur depending on the specific treatment.

Librela: Minimal side effects, though mild reactions like localized swelling or lethargy may occur temporarily.
Synovetin OA: Rare but potential risks include joint stiffness or localized inflammation immediately after injection.
Adequan: Occasional bruising at the injection site or mild gastrointestinal upset.

💡 Tip: Report any unusual symptoms to your vet immediately to adjust the treatment plan if needed.

Comment 8: “What are the long-term benefits of Spryng for advanced arthritis?”

Spryng provides significant benefits for dogs with advanced arthritis by mimicking natural cartilage cushioning.

Joint Protection: By replicating cartilage, it reduces stress on bones and slows further joint damage.
Pain Reduction: Enhanced joint cushioning alleviates pain, allowing dogs to regain mobility.
Longevity: Effects last longer than traditional treatments, reducing the frequency of interventions.

💡 Tip: Spryng is especially effective for older dogs that need substantial joint support.

Comment 9: “Can these injections prevent arthritis in younger dogs?”

Injections are not typically used preventively but can help slow progression in dogs predisposed to arthritis.

Risk Management: Adequan is sometimes used in young, active dogs prone to joint injuries to preserve cartilage health.
Genetic Factors: Breeds predisposed to hip or elbow dysplasia may benefit from early interventions like joint supplements combined with proper exercise.
Preventive Focus: Most injections are reserved for managing symptoms, so preventive care relies more on diet, exercise, and weight control.

💡 Tip: Regular veterinary check-ups can identify early joint issues, allowing for timely intervention.

Comment 10: “How do I choose the best injection for my dog?”

Choosing the right injection depends on your dog’s specific needs, condition severity, and overall health.

For Chronic Pain: Librela is excellent for long-term pain management in moderate to severe cases.
For Localized Arthritis: Synovetin OA is ideal for dogs with specific joint issues like elbow arthritis.
For Cartilage Support: Adequan works well in early-stage arthritis to slow cartilage degeneration.
For Severe Damage: Spryng offers a cushioning effect for advanced arthritis or significant cartilage loss.

💡 Tip: Consult your vet to evaluate your dog’s symptoms, medical history, and lifestyle before deciding on a treatment.

Comment 11: “How does arthritis progress if left untreated, and can injections halt this progression?”

Untreated arthritis in dogs leads to progressive joint damage, significantly impacting their mobility and quality of life.

Progression: As arthritis advances, cartilage deteriorates, causing increased friction between bones. This triggers inflammation, pain, and eventual joint deformity.
Impact on Mobility: Dogs may struggle with basic activities like climbing stairs, walking, or standing up. Over time, compensatory strain on other joints or muscles can worsen their condition.
Injections’ Role: Treatments like Adequan help slow cartilage degradation, while Librela alleviates pain to improve movement. Synovetin OA specifically targets inflammation, reducing further joint damage.

💡 Tip: Early intervention with a combination of injectables, physical therapy, and dietary adjustments can delay arthritis progression and preserve mobility.

Comment 12: “Can arthritis injections improve a dog’s mental well-being?”

Yes, by alleviating pain and restoring mobility, arthritis injections can significantly enhance a dog’s mental health.

Pain Relief: Chronic pain from arthritis often causes irritability, anxiety, or depression. Effective injections like Librela can eliminate this discomfort, allowing dogs to relax.
Restored Activity: Increased mobility enables dogs to engage in physical activities and play, which boosts their confidence and happiness.
Improved Bonding: Pain relief fosters better interaction between pets and their owners, strengthening the emotional connection.

💡 Tip: Monitor changes in your dog’s behavior after treatment to assess their mental and physical improvement.

Comment 13: “How do I know when my dog is ready for arthritis injections?”

Several signs indicate your dog may benefit from arthritis injections, depending on the severity of their condition and response to current treatments.

Behavioral Changes: Reduced interest in walks, reluctance to climb stairs, or difficulty standing up could signal the need for injectable therapies.
Ineffective Medications: If NSAIDs or oral supplements fail to manage symptoms, injections like Librela or Synovetin OA can provide better relief.
Joint-Specific Pain: For localized joint pain, injections like Synovetin OA are ideal.

Discover 🐶 Best Puppy Food for a Labrador Retriever

💡 Tip: Work with your veterinarian to evaluate your dog’s joint health through X-rays and physical exams before initiating injectable treatments.

Comment 14: “Are injections safe for senior dogs with arthritis?”

Injections are generally safe for senior dogs, often offering better alternatives to oral medications that may strain aging organs.

Targeted Action: Therapies like Librela and Synovetin OA work directly on pain pathways or inflammation, minimizing systemic impact.
Reduced Side Effects: Unlike NSAIDs, injections typically don’t affect the liver or kidneys, which are often vulnerable in senior dogs.
Customization: Veterinarians can tailor dosages and schedules to suit the specific needs of senior dogs.

💡 Tip: Regular blood work and monitoring ensure injections remain safe and effective for aging pets.

Comment 15: “How quickly do arthritis injections provide relief?”

The onset of relief varies by the injection type but is generally faster than oral medications.

Librela: Pain relief can be noticeable within 7 days of the first injection, with improvements increasing over time.
Synovetin OA: Dogs often experience reduced inflammation and pain within 1–2 weeks, with long-lasting effects up to a year.
Adequan: Benefits are typically observed after the second or third dose within a 2-week period.

💡 Tip: Monitor your dog’s activity levels and comfort during the initial weeks post-treatment to gauge effectiveness.

Comment 16: “Are there any contraindications for arthritis injections?”

Certain conditions may make arthritis injections less suitable or require additional precautions.

Existing Infections: Active infections near the injection site or systemic infections may increase the risk of complications.
Autoimmune Diseases: Dogs with immune-mediated conditions may require alternative treatments to avoid potential immune system interactions.
Pregnancy and Nursing: Some injections, like Synovetin OA, may not be recommended for pregnant or nursing dogs.

💡 Tip: Share your dog’s full medical history with your vet to determine the safest treatment plan.

Comment 17: “How do arthritis injections compare in cost to other treatments?”

While arthritis injections may have a higher upfront cost, they often provide long-term value compared to daily medications.

Frequency: Librela requires monthly injections, while Synovetin OA provides relief for up to a year, reducing overall treatment frequency.
Effectiveness: Improved mobility and reduced pain can minimize additional expenses on complementary therapies.
Reduced Side Effects: Avoiding complications from NSAIDs or other medications saves on potential medical interventions.

💡 Tip: Ask your vet about payment plans or insurance coverage to make these treatments more affordable.

Comment 18: “Can injections be used for dogs with mild arthritis?”

Yes, injections can be beneficial even in early-stage arthritis to slow progression and reduce pain.

Preventive Action: Adequan supports cartilage health, preventing further damage in dogs with mild arthritis.
Improved Mobility: Injections like Librela can enhance activity levels, delaying the need for more aggressive treatments.
Pain Management: Early intervention ensures that pain doesn’t escalate, preserving your dog’s quality of life.

💡 Tip: Combine early-stage injections with weight management and exercise to optimize joint health.

Comment 19: “What lifestyle changes should accompany arthritis injections?”

Injections work best when paired with supportive lifestyle modifications.

Weight Management: Keeping your dog at a healthy weight reduces strain on joints.
Low-Impact Exercise: Activities like swimming or gentle walks maintain mobility without stressing joints.
Supportive Bedding: Orthopedic beds help alleviate pressure on sore joints during rest.

💡 Tip: Avoid high-impact activities, like jumping or running on hard surfaces, to prevent further joint stress.

Comment 20: “What makes arthritis injections stand out in veterinary care?”

Arthritis injections represent a significant advancement in targeted, minimally invasive pain management for dogs.

Innovative Science: Treatments like Librela use cutting-edge monoclonal antibody technology to address pain at its source.
Convenience: Long-lasting relief reduces the burden of daily medication administration.
Improved Outcomes: By addressing pain and inflammation effectively, injections enhance dogs’ overall quality of life.

💡 Tip: Discuss these options with your vet to find the most effective solution tailored to your dog’s specific needs.