Advantage Multi vs. Revolution Plus vs. Nexgard Combo 🐾

When it comes to protecting your pets from the many dangers posed by parasites, choosing the right product is key. Advantage Multi, Revolution Plus, and Nexgard Combo each provide comprehensive protection, but they vary in the types of parasites they cover and their mode of application.

Key Takeaways: Quick Answers to Common Questions

• Which product offers the broadest spectrum of protection? Nexgard Combo covers fleas, ticks, heartworms, intestinal parasites, and mites.
• Which treatment is the best for flea control? Revolution Plus and Nexgard Combo are both excellent for rapid and long-lasting flea protection.
• What’s the best choice for pets with sensitive skin? Advantage Multi is a great topical option for pets with sensitive skin, as it provides broad coverage without the need for oral medications.
• How do these treatments compare for tick protection? Nexgard Combo provides the most robust tick protection, while Revolution Plus offers tick coverage for cats but not dogs.
• Which product is safest for young pets? Advantage Multi and Revolution Plus can both be used on kittens and puppies from 8 weeks of age, depending on weight.

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What Are the Key Differences Between Advantage Multi, Revolution Plus, and Nexgard Combo? 🧐📊

While all three treatments offer comprehensive protection, their differences lie in the parasites they target, mode of administration, and the specific animals they’re designed for. Understanding these differences will help you make the right choice based on your pet’s needs.

Product	Main Ingredients 🧪	Parasites Covered 🛡️	Form 💊	Suitable For 🐶🐱
Advantage Multi 🐕🐈	Imidacloprid, Moxidectin	Fleas, heartworms, hookworms, roundworms, whipworms, ear mites, sarcoptic mange	Topical	Dogs, cats
Revolution Plus 🐈	Selamectin, Sarolaner	Fleas, ticks, heartworms, ear mites, roundworms, hookworms	Topical	Cats only
Nexgard Combo 🐈	Esafoxolaner, Eprinomectin, Praziquantel	Fleas, ticks, heartworms, roundworms, hookworms, tapeworms, ear mites	Topical	Cats only

💡 Pro Tip: If you’re looking for the most comprehensive coverage, Nexgard Combo offers an impressive range of protection, especially for cats, by covering fleas, ticks, heartworms, and intestinal parasites. Advantage Multi is ideal if you prefer a product that works for both dogs and cats, while Revolution Plus is a top choice for feline tick control combined with other broad-spectrum protections.

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Which Product Provides the Best Flea Control? 🦟🐾

When it comes to flea control, all three products excel at protecting pets from these pesky parasites, but there are subtle differences in how fast they work and how long they last.

• Revolution Plus: Starts killing fleas within 6 hours and eliminates 100% of fleas within 24 hours. It also prevents flea eggs from hatching, which is crucial for breaking the flea lifecycle.
• Nexgard Combo: Similar to Revolution Plus, Nexgard Combo begins working on fleas within hours of application. It kills adult fleas and prevents infestations by attacking flea larvae.
• Advantage Multi: Offers strong flea protection by killing fleas within 12 hours of application. It’s highly effective for dogs and cats but doesn’t work as quickly as the other two products.

Product	Flea Killing Speed ⏱️	Long-Lasting Protection 🛡️
Revolution Plus 🐈	Kills fleas within 6 hours	Lasts up to 30 days
Nexgard Combo 🐈	Kills fleas within 8 hours	Lasts up to 30 days
Advantage Multi 🐕🐈	Kills fleas within 12 hours	Lasts up to 30 days

💡 Pro Tip: If your pet has a flea allergy or you need rapid flea control, Revolution Plus or Nexgard Combo are ideal choices due to their fast action. However, if you prefer a product that covers both dogs and cats, Advantage Multi provides robust flea protection across species.

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Which Product Offers the Best Protection Against Ticks? 🕷️

Tick protection is crucial, particularly if your pet is at risk of tick exposure due to outdoor activities or living in tick-heavy areas. Here’s how the products compare in terms of tick prevention:

• Nexgard Combo: Provides the most comprehensive tick protection for cats, killing multiple species of ticks, including black-legged (deer) ticks, American dog ticks, and lone star ticks. It offers 30 days of protection against new tick infestations.
• Revolution Plus: Also effective against ticks in cats, covering black-legged ticks, American dog ticks, and Gulf Coast ticks. It provides full protection against ticks for up to 30 days.
• Advantage Multi: Does not protect against ticks in either dogs or cats, so if tick protection is needed, it should be paired with a tick-specific treatment.

Product	Tick Protection 🕷️	Protection Duration ⏳
Revolution Plus 🐈	Yes (multiple species)	30 days
Nexgard Combo 🐈	Yes (multiple species)	30 days
Advantage Multi 🐕🐈	No	N/A

💡 Pro Tip: If tick protection is a priority, Nexgard Combo offers the most thorough coverage for cats, while Revolution Plus is another excellent choice. If you use Advantage Multi, you’ll need to pair it with a tick-specific product for full coverage.

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Which Product Provides the Broadest Protection Against Internal Parasites? 🦠

All three products provide robust protection against heartworms and various intestinal parasites, but they differ in the types of worms they cover:

• Nexgard Combo: Provides the broadest spectrum of protection, covering heartworms, roundworms, hookworms, and tapeworms. This makes it ideal for cats who are at risk of multiple intestinal worms.
• Advantage Multi: Covers heartworms, roundworms, hookworms, and whipworms. It is highly effective in preventing intestinal parasites but does not cover tapeworms.
• Revolution Plus: Protects against heartworms, roundworms, and hookworms in cats. It doesn’t cover tapeworms or whipworms, so additional deworming treatments may be needed depending on your pet’s exposure risk.

Product	Heartworm Protection ❤️	Roundworms & Hookworms 🐛	Tapeworm Protection 🦠	Whipworms 🐍
Nexgard Combo 🐈	Yes	Yes	Yes	No
Revolution Plus 🐈	Yes	Yes	No	No
Advantage Multi 🐕🐈	Yes	Yes	No	Yes

💡 Pro Tip: If your cat or dog is at risk of contracting tapeworms, Nexgard Combo is the best choice for comprehensive internal parasite protection. For dogs or cats that require protection against whipworms, Advantage Multi is ideal, though a separate tapeworm treatment may be needed.

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How Safe Are These Products for Puppies, Kittens, and Senior Pets? 🐾👶👵

Ensuring the safety of young or senior pets is critical when choosing parasite preventatives. Here’s how these products stack up in terms of age and weight requirements:

• Advantage Multi: Safe for dogs and cats from 7 weeks of age (and dogs weighing at least 3 lbs, cats weighing 2 lbs). It is a gentle topical treatment, making it a great choice for young puppies and kittens or senior pets with sensitive stomachs.
• Revolution Plus: Safe for kittens from 8 weeks of age (and weighing at least 2.8 lbs). It’s specifically designed for cats, offering a broad spectrum of protection for young and older felines alike.
• Nexgard Combo: Safe for kittens from 8 weeks of age, with a minimum weight requirement of 1.2 kg (2.6 lbs). Like Revolution Plus, Nexgard Combo is designed for *cats*, ensuring safe use even in young kittens or senior cats.

Product	Minimum Age 🐶🐱	Minimum Weight ⚖️
Advantage Multi 🐕🐈	7 weeks	1.4 kg (3 lbs) for dogs, 2 lbs for cats
Revolution Plus 🐈	8 weeks	1.25 kg (2.8 lbs)
Nexgard Combo 🐈	8 weeks	1.2 kg (2.6 lbs)

💡 Pro Tip: For puppies or kittens that need broad parasite protection early on, Advantage Multi is a great all-around choice for both dogs and cats. For young cats, both Revolution Plus and Nexgard Combo are excellent options depending on the range of parasite protection you need.

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How Do These Products Compare for Pets with Sensitive Skin or Allergies? 🐾❗

If your pet has sensitive skin or allergies, choosing a product that minimizes irritation is essential:

• Advantage Multi: As a topical treatment, Advantage Multi is gentle on the skin and designed to be safe for pets with sensitive skin. It’s free from harsh chemicals and provides broad-spectrum protection without oral ingestion, making it ideal for pets prone to food sensitivities or digestive issues.
• Revolution Plus: Also a topical treatment, Revolution Plus is generally well-tolerated by cats but can occasionally cause mild skin irritation at the application site. It’s a great option for pets that don’t tolerate oral medications well, but keep an eye on the application site after use.
• Nexgard Combo: Nexgard Combo’s topical application is also safe for most cats, but like any topical, it may cause mild redness or itching. Monitor your pet’s skin after the first application to ensure there are no allergic reactions.

💡 Pro Tip: For pets with sensitive skin or known allergies, Advantage Multi is the safest bet, as it’s been specially formulated to reduce the risk of irritation. Always monitor your pet for any reactions after applying topical treatments.

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Final Thoughts: Which Product Is Best for Your Pet?

Choosing between Advantage Multi, Revolution Plus, and Nexgard Combo depends on your pet’s specific needs and lifestyle. Nexgard Combo offers the most comprehensive protection for cats, while Advantage Multi is ideal for both dogs and cats requiring a wide range of internal and external parasite protection. Revolution Plus is perfect for cat owners needing flea, tick, and heartworm control in one convenient topical.

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Quick Recap: Key Points to Remember

• Nexgard Combo: Provides the most comprehensive parasite protection for cats, covering fleas, ticks, heartworms, and intestinal worms.
• Revolution Plus: Ideal for cat owners needing flea, tick, and heartworm control, with fast flea-killing action.
• Advantage Multi: Great for both dogs and cats, offering broad parasite coverage including heartworms, fleas, and whipworms, but no tick protection.
• Sensitive Skin: For pets with skin sensitivities, Advantage Multi is gentle and safe for both dogs and cats.
• Puppies and Kittens: All products are safe for young pets, but check weight and age requirements for proper use.

By assessing your pet’s needs, environmental risks, and health, you can confidently choose the best product to protect your furry friend year-round. 🐕🐈

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Comment 1: “Which product should I choose if my cat goes outdoors and is exposed to ticks?”

If your cat spends time outdoors, tick protection becomes a critical consideration, especially if they roam in areas where ticks are common. Both Revolution Plus and Nexgard Combo offer excellent tick coverage, but there are important distinctions that may influence your decision.

• Revolution Plus: Specifically designed for cats, Revolution Plus offers protection against several tick species, including black-legged ticks, American dog ticks, and Gulf Coast ticks. It provides 30 days of tick prevention, which is essential for outdoor cats who are at risk of picking up ticks in wooded areas or grassy fields. Revolution Plus also covers fleas, heartworms, and internal parasites, making it a well-rounded solution for outdoor cats.
• Nexgard Combo: Nexgard Combo also provides comprehensive tick protection, including against black-legged ticks, lone star ticks, and American dog ticks. What sets Nexgard Combo apart is its broad protection not only from fleas and ticks but also from tapeworms, a significant risk for outdoor cats that hunt. This makes Nexgard Combo particularly useful if your cat is exposed to a variety of parasites from its environment.
• Advantage Multi: Unfortunately, Advantage Multi does not protect against ticks, so if your cat is frequently outdoors and exposed to ticks, this would not be the best option. You would need to pair it with a separate tick prevention treatment if you choose Advantage Multi for heartworm and flea control.

💡 Pro Tip: If your cat frequently ventures outdoors, Nexgard Combo offers the most comprehensive parasite protection, including ticks, fleas, heartworms, and tapeworms. However, Revolution Plus is also a fantastic choice if your cat needs broad parasite coverage but isn’t at high risk for tapeworms.

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Comment 2: “My dog hates taking oral medications. Is there a good alternative to oral flea and worm treatments?”

For dogs that dislike taking oral medications, topical treatments like Advantage Multi can be a great alternative. Topical treatments are easy to apply and eliminate the need for pills, making them ideal for pets that are resistant to chewable tablets or capsules. Here’s why Advantage Multi might be the solution for your dog:

• Advantage Multi: This topical treatment is applied to the skin, usually between the shoulder blades, and it absorbs quickly into your dog’s system. It provides protection against fleas, heartworms, hookworms, roundworms, and whipworms, making it a broad-spectrum solution without the struggle of getting your dog to swallow a pill. Because it’s a topical solution, there’s no need to worry about your dog refusing to eat or experiencing digestive upset from an oral medication.
• Nexgard Combo and Revolution Plus: These are both topical options as well, but they are only available for cats. So, if your dog has issues with oral medications, these products won’t be suitable, but Advantage Multi can provide a similar level of protection in a form they might tolerate better.

💡 Pro Tip: For dogs who resist oral medications, Advantage Multi provides a stress-free alternative that still offers robust protection against a wide range of parasites. Be sure to apply it to clean, dry skin, and avoid bathing your dog for at least 48 hours after application to ensure full efficacy.

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Comment 3: “My cat has a flea allergy. Which product works fastest to stop fleas from biting?”

For cats with flea allergy dermatitis (FAD), stopping flea bites quickly is crucial to prevent allergic reactions and skin irritation. The best option for rapid flea control will depend on how quickly the product can eliminate fleas before they have a chance to bite.

• Revolution Plus: Revolution Plus begins killing fleas within 6 hours of application, which is extremely fast for a topical product. It provides comprehensive flea control by eliminating adult fleas and preventing new infestations. This quick flea-killing action helps to reduce the risk of flea bites, which is essential for cats with flea allergies.
• Nexgard Combo: Nexgard Combo also starts killing fleas within 8 hours of application, providing fast relief for cats that suffer from flea allergies. Because it prevents flea larvae from developing into adults, Nexgard Combo helps break the flea life cycle, reducing the overall flea population in your cat’s environment.
• Advantage Multi: While Advantage Multi is effective for flea control, it starts killing fleas within 12 hours, which is slower compared to Revolution Plus and Nexgard Combo. For a cat with a flea allergy, a faster-acting product like Revolution Plus or Nexgard Combo might provide quicker relief.

💡 Pro Tip: For cats with flea allergies, Revolution Plus is the fastest option for killing fleas and reducing the likelihood of bites, followed closely by Nexgard Combo. Both provide excellent protection and help prevent future infestations, but Revolution Plus might offer the quickest initial relief.

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Comment 4: “How do I decide which product is best for long-term protection against heartworms?”

Heartworm prevention is essential year-round, and choosing a product that provides reliable, long-term protection is critical to safeguarding your pet’s health. All three products—Advantage Multi, Revolution Plus, and Nexgard Combo—offer heartworm prevention, but your choice will depend on your pet’s lifestyle and other parasite risks.

• Advantage Multi: As a topical treatment, Advantage Multi provides excellent long-term protection against heartworms for both dogs and cats. It’s particularly useful for pets that need protection against heartworms and internal parasites like roundworms and hookworms. Because it also controls fleas, it’s a solid choice for comprehensive protection in a single application. However, Advantage Multi does not protect against ticks.
• Revolution Plus: Revolution Plus is specifically for cats and provides reliable heartworm protection alongside protection against fleas, ticks, and internal parasites. This makes it a great all-around option for cats that need both heartworm and tick control in one convenient topical treatment.
• Nexgard Combo: Nexgard Combo also offers long-term heartworm prevention in cats, with the added benefit of protecting against tapeworms—a feature not provided by Revolution Plus or Advantage Multi. It’s a top choice for cats that may also be exposed to ticks and intestinal parasites.

💡 Pro Tip: For dogs, Advantage Multi is an excellent choice for long-term heartworm prevention, especially if you want to avoid giving oral medications. For cats, both Revolution Plus and Nexgard Combo provide solid heartworm protection, but Nexgard Combo may be preferable if tapeworm protection is needed as well.

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Comment 5: “How can I ensure my pet is fully protected from intestinal worms? Are any of these products better for deworming?”

Intestinal worms can pose serious health risks to pets, and comprehensive deworming is an important aspect of parasite prevention. Here’s how the three products stack up when it comes to coverage against intestinal worms:

• Nexgard Combo: This product offers the most comprehensive protection against intestinal worms in cats, covering roundworms, hookworms, and tapeworms. It’s an excellent choice for cats that need a broad range of deworming in addition to protection from fleas and ticks.
• Advantage Multi: Advantage Multi is highly effective for dogs and cats, covering roundworms, hookworms, and whipworms. It’s a solid choice if your pet is primarily at risk for these worms but doesn’t need protection from tapeworms.
• Revolution Plus: Revolution Plus covers roundworms and hookworms, but does not protect against tapeworms or whipworms. If tapeworms are a concern, you’ll need to use an additional dewormer alongside Revolution Plus.

Product	Roundworms 🐛	Hookworms 🐍	Tapeworms 🦠	Whipworms 🦠
Nexgard Combo 🐈	Yes	Yes	Yes	No
Revolution Plus 🐈	Yes	Yes	No	No
Advantage Multi 🐕🐈	Yes	Yes	No	Yes

💡 Pro Tip: For full intestinal worm coverage, especially if tapeworms are a concern, Nexgard Combo is the best choice for cats. For dogs or cats that don’t require tapeworm protection but still need robust internal parasite control, Advantage Multi offers a well-rounded solution.