Efficacy of Zymox Otic Plus for Ear Infections in Dogs

Dog owners often dread the occurrence of ear infections in their pets. These common but unpleasant conditions can cause a variety of symptoms, including pain, itchiness, and inflammation. In their quest for an effective solution, many pet owners have turned to Zymox Otic Plus, an over-the-counter product purported to alleviate these symptoms. However, how beneficial and effective is Zymox for canine ear infections?

Understanding Ear Infections in Dogs

Ear infections in dogs are typically caused by bacteria or yeast, and certain breeds with floppy ears or allergies may be more susceptible. Symptoms can range from minor irritation and redness to severe pain and hearing loss, with other possible signs including head shaking, scratching at the ears, and unpleasant odors.

What is Zymox Otic Plus?

Zymox Otic Plus is an enzymatic solution designed for treating acute and chronic otitis externa—an inflammation of the outer ear canal—in dogs. The product contains a patented LP3 Enzyme System that reportedly reacts with the infectious pus and debris to form its antimicrobial properties.

The Benefits of Zymox Otic Plus

Recent studies and anecdotal evidence suggest that Zymox Otic Plus may be a potent alternative to antibiotics in managing ear infections in dogs.

  1. Antibacterial, Antifungal, and Anti-Inflammatory Properties: Zymox Otic Plus contains enzymes such as lactoperoxidase, lysozyme, and lactoferrin, which possess antimicrobial properties. Moreover, the product includes hydrocortisone, known for its anti-inflammatory effects, which can help reduce the itchiness and discomfort associated with ear infections.
  2. Non-Antibiotic Treatment: The increasing concern over antibiotic resistance has made Zymox an appealing option for pet owners. Its enzymatic system works differently than traditional antibiotics, reducing the risk of creating antibiotic-resistant strains of bacteria.
  3. Easy Application: Zymox is a topical treatment applied directly into the ear canal, making it easier for pet owners to administer at home.

Zymox Otic Plus Effectiveness and Limitations

While Zymox has demonstrated effectiveness in treating bacterial and yeast infections, it’s essential to note that it may not work for all types of ear conditions. For instance, Zymox is not designed to treat ear mites, which require different kinds of medications.

Additionally, in cases of severe infections or those involving the middle or inner ear, a veterinarian’s intervention is crucial as these may need stronger prescription medications or other treatments.

Precautions and Side Effects of Zymox Otic Plus

Zymox Otic Plus is generally safe, but like any medication, side effects can occur. Some dogs might have an allergic reaction to the product, manifesting as increased redness, itching, or swelling.

Before beginning any treatment, it’s vital to ensure the dog’s eardrum is intact, as applying any medication to a ruptured eardrum can lead to more severe issues. Therefore, if your dog has severe pain, loss of balance, or unusual eye movements, consult your vet before using Zymox or any other over-the-counter products.


Zymox Otic Plus appears to offer an effective, non-antibiotic alternative for treating ear infections in dogs. Its easy application and multi-pronged attack against bacteria, yeast, and inflammation make it a popular choice among pet owners. However, it’s important to remember that not all ear conditions can be treated with Zymox, and veterinary advice should always be sought for severe or recurring infections.

Frequently Asked Questions about Zymox Otic Plus

Can Zymox Otic Plus Resolve Canine Ear Infections?

Zymox Otic Plus, with its patented LP3 Enzyme System, can effectively combat bacterial and yeast infections in the external ear canal of dogs. This enzymatic solution breaks down infectious pus and debris, aiding the healing process. However, Zymox is not designed to treat all ear conditions, such as ear mites, or severe infections involving the middle or inner ear, which may require veterinary intervention.

Which Version of Zymox is Most Effective for Ear Infections?

For mild to moderate ear infections, regular Zymox Otic is often sufficient. However, Zymox Otic Plus, which contains an additional 1% hydrocortisone, may offer more relief for dogs suffering from particularly inflamed or itchy ears. It’s always important to choose the product that best fits your dog’s specific needs, and in doubt, consult with a veterinarian.

Does Zymox Otic Plus Treat Bacterial Infections?

Yes, Zymox Otic Plus can be effective against bacterial infections. The enzymes in this solution have antimicrobial properties that help combat bacteria, thereby aiding in the treatment of bacterial ear infections. However, this product should not replace professional veterinary care for severe or persistent infections.

Are There Any Side Effects Associated with Zymox Ear Drops?

Zymox Otic Plus is generally safe for use in dogs. However, some dogs may experience an allergic reaction to the product, resulting in symptoms like increased redness, itchiness, or swelling. If any of these or other adverse reactions occur, stop using the product and consult with a veterinarian immediately. It’s also crucial to ensure the dog’s eardrum is intact before applying Zymox or any other medication to prevent more severe complications.

Does Zymox Otic Plus Kill Ear Mites?

No, Zymox Otic Plus is not designed to treat ear mites. These parasites require a different kind of medication, typically involving a pesticide that is safe for use on pets. If you suspect your dog has ear mites, it’s crucial to consult a veterinarian for an accurate diagnosis and appropriate treatment.

How Frequently Should I Use Zymox for My Dog’s Ear Infection?

Zymox Otic Plus is typically applied once a day for 7 to 14 days. However, the duration and frequency can depend on the severity of the infection and the dog’s response to treatment. Always follow the manufacturer’s instructions or your veterinarian’s advice when using this product.

Can Zymox Otic Plus Prevent Future Ear Infections?

While Zymox Otic Plus is designed to treat existing infections, regular cleaning with a product like Zymox Ear Cleanser can help maintain ear hygiene and potentially prevent future infections. However, it’s important to remember that some dogs, particularly those with allergies or certain breeds with floppy ears, might be more susceptible to recurrent ear infections, necessitating ongoing management strategies.

Can I Use Zymox Otic Plus on Other Pets Besides Dogs?

Zymox Otic Plus is primarily marketed for dogs, but it’s also safe for use in cats. The product’s enzymatic solution can help alleviate symptoms of ear infections in both animals. However, if you plan to use this product on other types of pets, it’s recommended to consult a veterinarian first to ensure its safety and efficacy.

Can I Use Zymox Otic Plus for Puppies?

Yes, Zymox Otic Plus can be used safely on puppies. However, due to their more sensitive nature, it’s always recommended to consult with a veterinarian before starting any new treatment. Pay close attention to your puppy’s response to the product and discontinue use and contact your vet if any adverse reactions occur.

How Should Zymox Otic Plus Be Stored?

To maintain its efficacy, Zymox Otic Plus should be stored at room temperature and kept out of direct sunlight. Keep it out of the reach of children and pets to avoid accidental ingestion or misuse. Do not freeze the product, as this can negatively impact the effectiveness of the enzymes.

Does Zymox Otic Plus Expire?

Like most medications, Zymox Otic Plus does have an expiration date, which can usually be found on the product label. It’s crucial to adhere to this date to ensure the product’s safety and effectiveness. Using expired products can result in decreased effectiveness and potentially lead to complications.

Can I Use Zymox Otic Plus with Other Ear Medications?

Zymox Otic Plus should not be used in conjunction with other ear medications or cleaners, as they may disrupt the enzymatic activity of the product. If your pet requires additional medication, it’s best to consult your veterinarian to devise a safe and effective treatment plan.

What Should I Do If My Pet’s Condition Worsens or Does Not Improve with Zymox Otic Plus?

If your pet’s ear infection seems to worsen or doesn’t show any signs of improvement after a week of using Zymox Otic Plus, it’s critical to seek veterinary care. This could indicate a more serious infection or an underlying condition that requires professional intervention.

Can I Use Zymox Otic Plus If My Dog Has a Ruptured Eardrum?

Zymox Otic Plus should not be used if your dog’s eardrum is ruptured or suspected to be ruptured, as it could lead to more serious complications, including hearing loss. If your dog exhibits symptoms like loss of balance, unusual eye movements, or severe pain, seek immediate veterinary care.

How Long Does it Take for Zymox Otic Plus to Show Results?

While the exact timeline can depend on the severity of the infection and the dog’s overall health, many pet owners report seeing improvements within a few days of starting Zymox Otic Plus. In general, the full course of treatment lasts 7-14 days. If your pet doesn’t show any signs of improvement within a week, it’s recommended to consult your veterinarian.

Can Zymox Otic Plus Cause Discoloration or Staining?

Zymox Otic Plus is a clear solution and should not cause discoloration or staining on your pet’s fur or on fabric. However, it’s always a good idea to wipe away any excess solution from your pet’s fur after application to avoid any potential issues.

Is Zymox Otic Plus Safe to Use if My Pet is Pregnant or Nursing?

There’s currently no information suggesting that Zymox Otic Plus is unsafe for pregnant or nursing pets. However, as with any medication, it’s best to consult with a veterinarian before starting treatment to ensure it’s safe for both the mother and offspring.

Can I Use Zymox Otic Plus More Frequently Than Once a Day?

Zymox Otic Plus is generally recommended for use once a day. Using it more frequently may not increase its effectiveness and could potentially cause discomfort or irritation. Always follow the manufacturer’s instructions or your veterinarian’s guidance when using this product.

Can Zymox Otic Plus Be Used for Other Types of Infections?

Zymox Otic Plus is designed to treat ear infections, specifically bacterial and yeast infections in dogs and cats. It’s not meant to be used for other types of infections or on other parts of the body unless recommended by a veterinarian.

What Should I Do If Zymox Otic Plus Gets in My Pet’s Eye or Is Ingested?

If Zymox Otic Plus accidentally gets in your pet’s eye, rinse it thoroughly with water and seek veterinary advice. If your pet ingests a significant amount of the product, monitor for any signs of illness like vomiting, loss of appetite, or unusual behavior and consult with a veterinarian if any concerns arise.

Leave a Reply

Your email address will not be published. Required fields are marked *

Back to Top