Can Gabapentin Cause Constipation in Dogs?

Gabapentin is a medication commonly prescribed to dogs for the management of chronic pain and seizures. However, as with any medication, there can be potential side effects that pet owners should be aware of. One such side effect is constipation. In this article, we will discuss the potential for gabapentin to cause constipation in dogs and what pet owners can do to address this issue.

First, it is important to understand what gabapentin is and how it works. Gabapentin is a medication that belongs to a class of drugs known as anticonvulsants. It works by binding to a specific type of receptor in the brain, known as the alpha-2-delta subunit, which helps to reduce the release of certain neurotransmitters that are associated with pain and seizures.

While gabapentin is generally considered to be a safe medication for dogs, it can cause certain side effects, including constipation. Constipation is a condition in which a dog has difficulty passing stool or experiences less frequent bowel movements than normal. This can be caused by a variety of factors, including dehydration, a lack of fiber in the diet, or certain medications.

There have been reports of constipation being a side effect of gabapentin in both human and veterinary medicine. In a study published in the Journal of Veterinary Internal Medicine, researchers found that constipation was the most common gastrointestinal side effect reported in dogs receiving gabapentin. In another study published in the Journal of the American Veterinary Medical Association, researchers found that gabapentin was one of the most common medications associated with constipation in dogs.

While the exact mechanism by which gabapentin causes constipation is not well understood, it is thought to be related to the medication’s effects on the nervous system. Gabapentin can reduce the activity of certain nerve cells in the gut, which can slow down the movement of food and waste through the digestive system. This can lead to constipation.

To address constipation caused by gabapentin, pet owners can try a few different strategies. The first is to increase the amount of fiber in the dog’s diet. Foods high in fiber, such as fruits and vegetables, can help to keep the digestive system moving and prevent constipation. Pet owners can also try giving their dogs a small amount of canned pumpkin, which can act as a natural laxative.

Another strategy is to ensure that the dog is getting enough water. Dehydration can contribute to constipation, so it is important to make sure that the dog is drinking enough water. Pet owners can try adding a little bit of water to the dog’s food or offering a water fountain to encourage drinking.

Finally, pet owners should speak with their veterinarians about adjusting the dosage of gabapentin or switching to a different medication. In some cases, a lower dosage or a different medication may be more effective at managing the dog’s pain or seizures without causing constipation.

In conclusion, constipation is a potential side effect of gabapentin in dogs. Pet owners should be aware of this potential side effect and take steps to address it if it occurs. By increasing the amount of fiber in the dog’s diet, ensuring the dog is getting enough water, and speaking with their veterinarian about adjusting the dosage or switching to a different medication, pet owners can help to alleviate constipation caused by gabapentin. It is important to note that each dog may react differently to the medication and it is vital to consult with a veterinarian if any side effects are noticed.


Hannah Elizabeth is an English animal behavior author, having written for several online publications. With a degree in Animal Behaviour and over a decade of practical animal husbandry experience, Hannah's articles cover everything from pet care to wildlife conservation. When she isn't creating content for blog posts, Hannah enjoys long walks with her Rottweiler cross Senna, reading fantasy novels and breeding aquarium shrimp.

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