Is Vetoryl Safe for Dogs?

Is Vetoryl safe for dogs? I’ve heard many people on social media sites asking this question. Some have said it killed their dogs and other animals, while others have said that it’s worked well for them. So what is happening here? Is Vetoryl being banned or is the FDA recalling it because it actually kills dogs?

Vetoryl Killed My Dog

“Vetoryl killed my dog. It exacerbated the health conditions in my dog’s body which led to his death. I didn’t find out that Vetoryl can cause very serious side effects.”

“My dog died while on treatment with Vetoryl. I want to share the story with others so that they can be aware of the risks of this drug and make the right choices when it comes to their pets’ health.”

“I lost my beloved dog last week after he was prescribed Vetoryl. He had Cushing’s Disease and was diagnosed a year ago, although we believe he had it for much longer.

We first noticed that he would pant excessively, even when sleeping, so we took him off the medicine for a few days to see if it stopped. Then he started panting more and couldn’t sleep without it.

The next day, he started shivering and could barely get up. We rushed him to the emergency vet where they did an ultrasound and determined that his liver was failing.

They gave us several options: euthanasia, blood transfusions (which would only buy him a few days), or hospitalization for 5-7 days with fluids and potential surgery. I opted for the hospital option because Max was still alert, responsive, and seemed ‘normal’ otherwise.

After 3 days at the hospital, they concluded that there was nothing else they could do and recommended euthanasia.”

Is Vetoryl safe for dogs?

Vetoryl® is generally well-tolerated by most dogs, and it is advised that you follow the directions and use the medication only as prescribed. However, many dog owners are wary about using this prescription drug because of the many side effects that have been reported.

Some of the symptoms associated with Vetoryl include:

  • Rapid breathing
  • Lack of coordination
  • Seizures
  • Lethargy
  • General malaise
  • Vomiting and diarrhea

It is important to watch your dog closely while they are on any new medicine to make sure they don’t have any negative side effects. Some of these side effects can be serious and require immediate attention, so it’s important to know what to look for.

What happens if a dog gets too much Vetoryl?

A Vetoryl overdose can cause a dog to become lethargic, vomit, and seizure. In some cases, the side effects can be serious, even life-threatening.

The main ingredient in Vetoryl is trilostane, which works by blocking the production of cortisol in the adrenal glands. This can be a very effective way to treat Cushing’s disease, but it comes with some risks. One of those risks is an overdose, which can occur if you give your dog too much Vetoryl without knowing it.

“I gave my dog Vetoryl twice a day, and he died. This is what happened. My vet prescribed Vetoryl for my dog’s Cushing’s disease. He had been urinating all over the house, panting, and losing weight. So I asked my vet if this medicine was safe to give him long-term and he said yes that it would not hurt his liver like the other drug (Lysodren) that he could have prescribed. Well, on Jan 26th, my dog died. I did not know until after he passed away that there are many people out there who have lost their dogs to this drug too!”

What drugs interact with Vetoryl?

Trilostane should be used cautiously in dogs with lung, kidney, or liver disease, or diabetes mellitus. It’s also important to tell your veterinarian about any other medications your pet is taking before giving Vetoryl® (trilostane). Some drugs that may interact with Vetoryl include:

  • ACE inhibitors
  • Potassium-sparing diuretics (e.g., spironolactone)
  • Aminoglutethimide
  • Ketoconazole

What are the clinical signs of Cushing’s disease in a dog?

Cushing’s disease is caused by abnormal secretion of corticotropin from the pituitary gland, leading to an overproduction of cortisol. Dogs with Cushing’s disease may have some or all of the following clinical signs:

  • Increased drinking and urination
  • Increased hunger
  • Weight loss and muscle wasting
  • Potbelly appearance
  • Thinning hair coat
  • Panting and lethargy
  • Recurrent skin infections

Positive reviews of Vetoryl

Vetoryl reviewers are impressed by how well the medication works, with many saying it helped to keep their pets feeling good for years. The capsules are easy to administer, and most dogs don’t mind taking them.

However, there’s some concern about the high cost of Vetoryl. Many owners say they had to switch medications because they couldn’t afford it anymore. There are also reports of side effects like upset stomach and diarrhea.

If you’re looking for a more affordable treatment option, check out our review of the best dog adrenal supplements.

“Vetoryl is the only product that doesn’t seem to make my dog sad, and I have tried a LOT. It has been a lifesaver for my dog. I thought that he was going to pass away due to his hyperthyroid, but luckily with Vetoryl it has kept him alive for a lot longer than originally expected.”

“Vetoryl did not put my dog to sleep. He was 13 years old, and his adrenal glands were failing, which made his life miserable. We had to make the decision to put him down. Vetoryl was a miracle drug for him. He went from being lethargic and grumpy to happy and playful. The cost of Vetoryl is nothing compared to the cost of the other drugs that are available that have the same side effects as Vetoryl but with less success. I’m not in any way trying to be rude – I just feel bad that your dog had problems with this drug since it gave my dog such a great quality of life for the last year or so of his life.”

“I have been using Vetoryl for my Cushings Dog. He is doing very well. He had the side effect of diarrhea but that has since subsided. I am very pleased with this product and would recommend it to anyone who is having problems with their pet. Have recommended it to friends who have older dogs and I will continue to recommend it.”

“My 12-year-old Boston Terrier with adrenal issues used this for about 2 years now, I believe it does work as her symptoms have improved greatly over the years. It does need a vet prescription and there are side effects of panting and some diarrhea which can be controlled with diet changes and probiotics. All in all, we are satisfied with this medication.”

Conclusion of Vetoryl killing dogs

The drug Vetoryl is used to treat Cushing’s disease in dogs. It is a steroid that works by blocking the production of cortisol. This allows the adrenal glands to produce less cortisol, which can help to control symptoms such as excessive thirst and urination.

Vetoryl is often considered a last-resort treatment option because it can cause serious side effects if not used correctly. The drug can cause sodium retention, which can lead to high blood pressure and heart failure. Vetoryl may also increase the risk of diabetes, osteoporosis, muscle weakness, and impaired kidney function.

If you have questions about your dog’s treatment plan, talk with your veterinarian about any concerns you may have about his management plan for Cushing’s disease.

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Hannah Elizabeth is an English animal behavior author, having written for several online publications. With a degree in Animal Behaviour and over a decade of practical animal husbandry experience, Hannah's articles cover everything from pet care to wildlife conservation. When she isn't creating content for blog posts, Hannah enjoys long walks with her Rottweiler cross Senna, reading fantasy novels and breeding aquarium shrimp.

3 Responses

  1. I believe vetoryl ultimately killed my dog. She was finally diagnosed with Cushing, however; we believe she had it for several years. The vet put her on vetoryl one time a day. By day 5, my Chloe was unable to walk. She lost all motor control. We immediately stopped the medicine and took her back to the vet. They said her kidneys were shutting down and hospitalized her for 5 days with fluids and put her on a chicken and rice diet. Her kidney levels improved but were still elevated. From there we have her a fluid shot 3x a week for 2 weeks and did another round of blood work. The levels went back up so we continued with fluids every other day. We were told there was no side effects anywhere they could find if vetoryl causing kidney failure, however, my Chloe was fine other than the symptoms from Cushing. My sweet sweet girl started vetoryl on 2/15/2022 and just passed away yesterday 3/20/2022. Yes, she was elder, but there was no signs of any kidney concerns until starting vetoryl.

  2. The vet said my dog had Cushing’s disease. She was drinking a lot of water and she was hungry all the time. More like diabetic. It was like the medication was eating her insides. We could feel her ribs and she stopped drinking water and eating. Her hair came out and it was just skin showing on her neck, and down her back was bare. She suffered. I suggest anyone giving this medicine to their pet investigate it and don’t start with a high dose. She passed today. The vet gave her too high of a dose to start. She was dead in a few weeks. Before this medicine, she was a happy dog and could get around good.

  3. I do not recommend giving your beloved pets vetoryl, my baby girl was diagnosed with Cushing disease within 3 weeks of taking this killer drug my baby was gone, I wish I had never given her the medication. If you are prescribed vetoryl please please research it first before giving it to your babies

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