How Much Zyrtec Can I Give My Dog?

As with any medication, you should follow the dosage instructions that come with your Zyrtec and consult your veterinarian if you are in doubt or want further advice. But how much Zyrtec can you give a dog?

How Many Zyrtec Can I Give My Dog

How many Zyrtec tablets can I give my dog?

The recommended dose is 0.5 mg per pound of body weight once or twice a day, and the maximum dosage of Zyrtec should not exceed 20 mg. So if your dog weighs 20 pounds, you could give him a single 10 mg tablet.

Zyrtec dosage for dogs by weight
Dog’s weight Zyrtec dosage
5 lbs ½ of a 5 mg tablet
10 lbs one 5 mg tablet
20 lbs one 10 mg tablet or two 5 mg tablets
50 lbs two 10 mg tablets
80 lbs two 10 mg tablets
100 lbs two 10 mg tablets

Can dogs overdose on Zyrtec?

Zyrtec is very safe and effective for dogs, but it can be toxic when ingested in large amounts. If you suspect that your dog has eaten too much Zyrtec, take him to the vet as soon as possible.

What are the side effects of Zyrtec in dogs?

The main side effects of Zyrtec include drowsiness and dry mouth, but these are usually mild and tend to go away after a few days of treatment. Zyrtec is not recommended for dogs that are hypersensitive to cetirizine or other antihistamines.

Other less common side effects include nausea, vomiting, diarrhea, and constipation. In rare cases, dogs may experience serious side effects such as seizures or low blood pressure.

Does Zyrtec help dogs with itching?

Yes, but it is not a cure for dog allergies. It is a medication used to ease the symptoms of allergies.

Zyrtec is sometimes prescribed for dogs as a treatment for atopic dermatitis, which is a skin condition characterized by itching and inflammation of the skin. It’s not approved by the U.S. Food and Drug Administration (FDA) for this purpose but has been shown to be effective in some cases.

Benadryl vs Zyrtec for dogs

For dogs, Benadryl and Zyrtec are both antihistamines. They work by blocking histamine, a chemical released in the body during an allergic reaction. Histamine can cause itching, swelling, redness and other symptoms of allergies.

Benadryl is a brand name for diphenhydramine while Zyrtec is a brand name for cetirizine. Both medications are available over-the-counter at most pet pharmacies and usually come in liquid or chewable tablet form.

Diphenhydramine is an older drug and has been used as a sedative for decades. Cetirizine does not have this effect, but it does have fewer side effects than diphenhydramine.

Some dogs do better on one medication than the other, but there is no way to know until you try them out yourself.

Zyrtec and Benadryl together for dogs?

It is not recommended to give your dog both medications at the same time. The combination of both medications could cause an overdose or toxic reaction.

It is advised to give Benadryl or any other antihistamine at least 8 or 12 hours before or after giving Zyrtec. They also block histamines but have different properties, which may lead to a negative interaction if taken together.

Both medications should be avoided in dogs with heart disease or seizure disorders due to their potential for increasing heart rate and lowering blood pressure.

It is important to follow your vet’s instructions when it comes to giving your dog any medication. If you have any questions or concerns about giving your pet any medications, please call your vet for clarification before administering anything to your pet.

Which antihistamine is best for dogs?

The most common antihistamines are diphenhydramine (Benadryl), loratadine (Claritin), and cetirizine (Zyrtec). These meds all do the same thing: they block the release of histamines in your dog’s body. Histamines cause allergic symptoms like itching and swelling, so blocking them with an antihistamine will help reduce those symptoms.

There are many different kinds of antihistamines, but the ones listed here are among the most common and effective. They’re also available in liquid form, which makes it easy to give them to your dog as needed.

How can I treat my dog’s allergies at home?

There are many different treatments for allergies in dogs, depending on the severity of the condition.

For mild to moderate allergies, a vet might suggest an antihistamine or steroid. These can help reduce symptoms and make your dog more comfortable.

Treatments for severe allergies include steroids, antihistamines, and antibiotics. These medications are usually given orally but may also be given as injections depending on the severity of the problem and what has been prescribed by your veterinarian.

If your dog has severe allergies it’s important that you address this problem as quickly as possible so that they can receive proper treatment before they develop infections or other complications due to their condition.

What is a natural antihistamine for dogs?

There are several natural antihistamines that can be used to help dogs with allergies. These include:


These organisms help to improve the immune system. Most dogs will benefit from probiotics in some way, but they are especially useful for dogs with allergies.

Fish oil

Fish oil contains omega-3 fatty acids that have many health benefits including reducing inflammation and allergies. It also helps to promote circulation in your dog’s body which helps them feel better overall.

Chamomile tea

Chamomile is an herb that has been used in traditional medicine for centuries. It can be added to your dog’s water or food, but do not give it straight from the tea bag because it may be too concentrated. You can also add chamomile extract to your dog’s treat recipes to give him relief from his symptoms.

Licorice root

Licorice root is another herb that has been used in traditional medicine for centuries and it has anti-inflammatory properties which can help relieve allergies in dogs.


Quercetin is a powerful antioxidant that can be found in many fruits, vegetables, and herbs. It has been used for centuries as an anti-inflammatory and to help with allergies and asthma. Quercetin can also be used to treat eczema, dermatitis, psoriasis, and other skin conditions.

Quercetin is safe for dogs to take as a supplement or in food. It is non-toxic and does not affect the liver or kidneys like some other medications do. It also doesn’t have any side effects like vomiting or diarrhea that some other medications do.

It’s important to note that quercetin can interfere with some medications by making them less effective or even causing dangerous side effects. If you’re giving your dog any medications, talk to your veterinarian before adding quercetin to his diet.


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Hannah Elizabeth is an English animal behavior author, having written for several online publications. With a degree in Animal Behaviour and over a decade of practical animal husbandry experience, Hannah's articles cover everything from pet care to wildlife conservation. When she isn't creating content for blog posts, Hannah enjoys long walks with her Rottweiler cross Senna, reading fantasy novels and breeding aquarium shrimp.

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