50mg Trazodone for Dogs Dosage Chart

The usual starting dose of trazodone for dogs is 0.9 to 1.3 mg per pound of body weight, given once daily and then gradually tapered up to effect. This may be increased by your veterinarian based on your dog’s response to the medication.

Dog’s weight (lbs) Trazodone dosage (50 mg tablet)
10 to 20 lbs 1/2 tablet of 50 mg
21 to 30 lbs 1 tablet of 50 mg
31 to 40 lbs 1 tablet of 50 mg
41 to 50 lbs 1 and 1/2 tablets of 50 mg
51 to 60 lbs 2 tablets of 50 mg
61 to 70 lbs 2 tablets of 50 mg
71 to 90 lbs 2 and 1/2 tablets of 50 mg

Trazodone 50mg for dogs reviews

Trazodone is a commonly prescribed antidepressant for dogs, but as with any medication, it’s important to consider the potential benefits and drawbacks. Here’s a rundown of what to keep in mind when deciding whether Trazodone is right for your furry friend.


Trazodone is typically used to treat anxiety, aggression, and phobias in dogs. It can also help with obsessive-compulsive behaviors and depression.


Trazodone is relatively safe and has few side effects in dogs. It’s also relatively inexpensive compared to some other medications. In addition, it’s been widely used in veterinary medicine and has a well-established safety profile.


One potential downside of Trazodone is that it can cause drowsiness, which can make it difficult for dogs to perform certain tasks. In some cases, it may also cause gastrointestinal upset. Trazodone can interact with other medications, so be sure to discuss any other drugs your pet is taking with your veterinarian before starting treatment.

Side Effects:

Common side effects of Trazodone in dogs include drowsiness, decreased appetite, and diarrhea. More serious side effects are rare but can include vomiting, lethargy, and an increased risk of seizures.


Trazodone is generally considered to be safe when used as directed. However, it can be toxic in large doses, so be sure to follow your veterinarian’s instructions carefully.

Drug Interactions:

Trazodone can interact with a number of other medications, including pain relievers, anti-anxiety medications, and other antidepressants. Be sure to discuss any other drugs your pet is taking with your veterinarian before starting treatment.


Trazodone is not recommended for dogs with liver or kidney disease, as well as dogs who are pregnant or nursing.

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Research and Study:

There have been several studies conducted on the use of Trazodone in dogs, and the results have been promising. However, more research is needed to determine its long-term safety and effectiveness.


If Trazodone isn’t right for your dog, there are several other medications that can be used to treat anxiety, aggression, and other behavioral problems. These include anti-anxiety drugs like Fluoxetine, behavioral modification therapy, and pheromone therapy.

With the help of your veterinarian, you can find the right solution to help your furry friend live their best life.

How does trazodone make dogs feel?

To put it simply, trazodone is a sedative-antidepressant that works by increasing the levels of serotonin in the brain, leading to a calming effect. This helps dogs to feel more relaxed and less anxious. It’s like a warm blanket for the brain, helping dogs to settle down and sleep peacefully.

However, the effects of trazodone can vary from dog to dog. Some dogs may feel more drowsy and lethargic after taking the medication, while others may still be alert but more relaxed. Give the medication exactly as directed by your veterinarian, as giving too much can lead to side effects like dizziness, confusion, and difficulty walking.

In general, trazodone is a safe and effective medication for helping dogs with behavioral problems feel more at ease. Just remember, it’s not a magic solution, and it may take a few doses before you notice a noticeable improvement in your dog’s behavior. But with patience and proper use, trazodone can be a valuable tool in helping your furry friend feel more relaxed and content.

How long does it take for trazodone to kick in a dog?

Typically, it takes anywhere from 30 minutes to an hour for trazodone to start working on dogs. However, the exact time frame can depend on several factors such as the size of your dog, the dose of the medication, and the individual metabolism of your pet.

Keep in mind that trazodone works best when taken regularly at the same time every day. Consistency is key when it comes to medication, and giving it at the same time each day can help ensure that your pet gets the maximum benefit from the drug.

Trazodone may take several days or even weeks to reach its full effect. So, if you’re looking for immediate relief for your pet, this medication may not be the best choice. But, if you’re looking for a long-term solution, then trazodone could be just what the vet ordered.

How many hours does trazodone last in dogs?

The length of time trazodone lasts in dogs can vary depending on several factors such as the dog’s size, weight, and overall health. On average, the effects of trazodone can last anywhere from 6 to 12 hours in most dogs. However, some dogs may experience a shorter or longer duration of the medication’s effects.

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Trazodone is a short-acting medication, meaning that it’s designed to provide quick relief for anxiety or behavioral issues. As a result, it’s typically given once or twice a day, depending on the severity of the issue. If you’re concerned about how long trazodone lasts in your dog, it’s always best to talk to your veterinarian.

Trazodone can interact with other medications, so it’s important to let your vet know about any other medications your dog is taking. This can impact how long trazodone lasts in your furry friend and whether it’s the right medication for them.

What happens if I give my dog too much trazodone?

Overdosing on trazodone can cause a range of side effects, ranging from mild to severe. Here’s a list of what could happen if you give your furry friend too much of this medication:

  1. Drowsiness and sedation: Trazodone is a sedative, so if your dog takes too much, they’ll become excessively drowsy and may even fall asleep.
  2. Low blood pressure: Overdosing on trazodone can cause a drop in blood pressure, which can lead to weakness, fainting, or even coma.
  3. Vomiting and diarrhea: Trazodone can cause digestive issues, such as vomiting and diarrhea if taken in excess.
  4. Respiratory depression: Overdosing on trazodone can lead to respiratory depression, meaning your dog’s breathing rate will slow down. This can be life-threatening if left untreated.
  5. Uncoordinated movements: Trazodone can also cause your dog to become unsteady on their feet and have trouble walking.
  6. Seizures: In severe cases, an overdose of trazodone can cause seizures, which can be dangerous for your dog’s health.

It’s always best to err on the side of caution when giving your dog medication. If you suspect that your dog has been given too much trazodone, it’s important to seek veterinary help immediately. Your veterinarian will be able to assess your dog’s condition and recommend the best course of action.

Is there an alternative to trazodone for dogs?

These alternatives are just a few of the many natural and safe options available on Amazon for dogs in need of stress and anxiety relief. Whether you choose to go with a hemp oil, passion flower, or any of the other options, be sure to speak with your vet to determine the best course of treatment for your furry friend.

  1. Hemp Oil for Dogs – This all-natural oil is made from pure hemp extract and is a great option for dogs struggling with anxiety, stress, and pain.
  2. Passion Flower – This herb is known to calm the nervous system and can be used as a natural alternative to Trazodone.
  3. Chamomile – Chamomile is a natural sedative that is often used to treat insomnia and anxiety in dogs. It’s gentle, non-toxic, and readily available on Amazon.
  4. Valerian Root – This root has been used for centuries to treat anxiety and restlessness in both humans and dogs. It’s considered a safe and natural alternative to Trazodone.
  5. Rescue Remedy – This homeopathic remedy is made from a blend of five Bach flower essences and can be used to calm and soothe dogs in stressful situations.
  6. Melatonin – This hormone is naturally produced by the body and is often used to regulate sleep patterns. It’s available in a supplement form and can be a safe and effective alternative to Trazodone for dogs.
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Conclusion of 50mg trazodone for dogs

Trazodone is a medication commonly prescribed to dogs for a variety of mental health issues, including anxiety and depression. But like all drugs, it has its pros and cons, and it’s important to weigh the benefits and risks before giving it to your furry friend.


Effective for anxiety and depression – Trazodone has been found to be effective in reducing symptoms of anxiety and depression in dogs, making it a good choice for pet owners seeking a solution to their dog’s behavioral issues.

Versatile use – Trazodone can be used to treat a range of mental health issues in dogs, including separation anxiety, fear of loud noises, and obsessive-compulsive disorders.

Safe with minimal side effects – Trazodone is generally considered safe for dogs, with minimal side effects, such as drowsiness, which is usually temporary and goes away after a few days.


Not suitable for all dogs – Trazodone may not be the right medication for every dog, and it is important to consult with your vet to determine if it is the best choice for your pet.

Can cause drowsiness – As mentioned, one of the most common side effects of Trazodone is drowsiness, which can be a problem for dogs that need to be active and alert.

Can interact with other medications – Trazodone can interact with other medications, such as heart medication, so it’s important to let your vet know about all medications your dog is taking before starting Trazodone.

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