🐾 Galliprant for Dogs: Is the 60mg Dose Better than 100mg? Everything You Need to Know!

Galliprant is a non-steroidal anti-inflammatory drug (NSAID) commonly used to treat pain and inflammation in dogs suffering from osteoarthritis. It offers various dosages, with 60mg and 100mg being the most commonly prescribed for larger dogs.


🐕 Key Takeaways: Quick Answers About Galliprant Dosing

  • Is 60mg better than 100mg for my dog? It depends on your dog’s weight. The 60mg dose is appropriate for dogs in the 45-75 lb range, whereas the 100mg dose is better suited for larger dogs over 75 lbs.
  • Can I split a 100mg tablet? No, the 100mg tablet is not scored and should not be broken in half, making the 60mg a better option for precise dosing.
  • Is Galliprant safe? Yes, it is generally safe, but as with any medication, there are potential side effects such as vomiting or diarrhea.
  • How do I know if my dog needs a lower dose? Watch for side effects such as lethargy, loss of appetite, or vomiting. Always consult your vet if these occur.

💊 What’s the Difference Between Galliprant 60mg and 100mg for Dogs?

The primary difference between the 60mg and 100mg doses of Galliprant is the intended weight range of the dog being treated. The dosing chart (provided in the image) outlines the correct dosage based on your dog’s weight.

Weight Range (lbs)Recommended Galliprant Dose💡 Pro Tip
8-15 lbs0.5 tablet of 20mgSmall dogs need precise, low-dose tablets.
15.1-30 lbs1 tablet of 20mgIdeal for smaller breeds.
30.1-45 lbs0.5 tablet of 60mgMid-sized breeds often require moderate doses.
45.1-75 lbs1 tablet of 60mgThe 60mg tablet suits large breeds.
75.1-150 lbs1 tablet of 100mg100mg is best for extra-large dogs, but avoid breaking tablets in half.

💡 Expert Insight: The 60mg tablet is often more versatile due to its scored design, allowing it to be easily halved for dogs that need intermediate doses. In contrast, the 100mg tablet cannot be split, limiting its flexibility.


⚖️ Why Might the 60mg Dose Be More Suitable Than 100mg?

For dogs weighing between 45-75 pounds, the 60mg dose is optimal. The key benefit of the 60mg dose lies in its flexibility:

  • Precision: The 60mg tablet is scored, meaning you can split it if your dog needs only half a dose. This makes it more adaptable for dogs that might require slightly adjusted doses due to weight fluctuation or specific health conditions.
  • Avoid Overmedication: If your dog falls between 60-75 lbs, the 100mg tablet might provide more than the needed dose, increasing the risk of side effects such as vomiting, diarrhea, or lethargy.
  • Accuracy: The 100mg tablet should not be broken in half, as this can lead to uneven dosing. A 60mg dose ensures that even if a smaller dosage is needed, you can provide accurate treatment without concern.

💡 Pro Tip: If your dog’s weight fluctuates, opting for the 60mg dose provides more flexibility without risking overmedication.


🚨 What Are the Potential Side Effects of Galliprant?

While Galliprant is a safer NSAID option compared to traditional COX-inhibitors, side effects can still occur. Based on clinical trials, the most common side effects include:

Side EffectFrequency (Galliprant Group)Frequency (Control Group)💡 Pro Tip
Vomiting24 dogs9 dogsOffer small meals and monitor for improvement.
Diarrhea17 dogs13 dogsEnsure hydration and contact the vet if persistent.
Loss of Appetite9 dogs7 dogsServe bland food to stimulate eating.
Lethargy6 dogs2 dogsKeep your dog comfortable and rested.
Buccal Ulcers1 dog0 dogsReport to the vet immediately if this occurs.
Immune-mediated Hemolytic Anemia1 dog0 dogsThis is very rare but serious. Seek emergency care if noticed.

💡 Expert Insight: Vomiting and diarrhea are the most frequently reported side effects. In most cases, these symptoms are mild and resolve on their own, but consult your vet if they persist beyond a day.


💡 Is Galliprant Safe for Long-Term Use at 60mg or 100mg?

Galliprant is designed to be safe for long-term use in treating osteoarthritis in dogs, even at higher doses such as 100mg, provided the dog’s weight and health condition match the prescription guidelines. The key is using the lowest effective dose for the shortest duration needed to manage pain.

However, long-term use of NSAIDs in dogs can still present risks, including kidney or liver strain. It’s essential to have regular vet check-ups, particularly if your dog is on a higher dose like 100mg, to monitor for any early signs of organ strain.

💡 Pro Tip: Use the lowest possible dose that controls your dog’s pain, and regularly consult your vet to adjust the dose as needed. For dogs weighing closer to 75 lbs, starting with the 60mg dose may be preferable to reduce unnecessary exposure to a higher dose.


📊 Galliprant 60mg vs. 100mg: Quick Comparison

Feature60mg100mg💡 Pro Tip
Best for Dogs Weighing45-75 lbs75-150 lbsAdjust based on your dog’s exact weight for precise dosing.
Can It Be Split?Yes (scored tablet)NoChoose 60mg if you need flexibility in dosing.
Long-Term UseSafe with monitoringSafe with monitoringRegular vet visits can prevent organ strain.
Most Common Side EffectVomitingVomitingMonitor for digestive issues and adjust diet accordingly.
FlexibilityHighLowThe 60mg dose allows for more adaptable treatment.

🗝️ Key Takeaways About Galliprant for Dogs

  • 60mg tablets offer more dosing flexibility for medium to large dogs and can be split for precision, making it a better option for many owners.
  • 100mg tablets are best suited for larger dogs over 75 lbs, but they cannot be split, limiting their dosing adaptability.
  • Monitor for side effects like vomiting or diarrhea and consult your vet regularly to ensure the dose remains appropriate for your dog’s changing health.
  • Long-term safety is possible, but regular check-ups are essential to prevent potential organ issues, particularly when using higher doses.

In conclusion, Galliprant 60mg is often better than 100mg for dogs in the 45-75 lb range, providing more flexibility and reducing the risk of overmedication. For dogs over 75 lbs, the 100mg tablet is suitable but requires strict adherence to dosing guidelines. Always work closely with your vet to determine the best dosage for your dog’s unique needs, and keep an eye out for any adverse reactions to ensure their comfort and health. 🐕


Comment 1: My dog weighs 70 pounds. Should I be using the 60mg or 100mg dose of Galliprant?

For a 70-pound dog, the 60mg dose of Galliprant is typically more appropriate based on the dosing guidelines. Since your dog falls within the 45-75 pound range, 1 tablet of 60mg daily is recommended. The benefit of using the 60mg dose is its accuracy and flexibility. The 60mg tablet is scored, meaning it can be halved if necessary, giving you more control over the dosage if any adjustments are needed later.

On the other hand, the 100mg tablet is designed for dogs over 75 pounds, so administering this to a 70-pound dog may result in overmedication, which could increase the risk of side effects such as vomiting or diarrhea. Moreover, the 100mg tablet cannot be split, so it’s less flexible for dogs hovering near the weight cutoff.

💡 Pro Tip: If your dog’s weight fluctuates or they are on the lower end of the 45-75 pound range, stick with the 60mg dose to ensure they get the right amount without unnecessary risks.


Comment 2: Can I break the 100mg Galliprant tablet in half to give my dog the right dose?

No, the 100mg Galliprant tablet should not be broken in half. Unlike the 60mg tablet, which is scored for easy splitting, the 100mg tablet is not designed to be divided. This means there’s no guarantee that each half will contain an even distribution of the active ingredient, making the dose inaccurate. Breaking the 100mg tablet may result in uneven dosing, which could either underdose your dog or lead to an overdose.

If your dog needs a dose lower than 100mg, it’s best to switch to the 60mg tablet, which provides the flexibility to administer a precise dose, especially for dogs that fall within the 45-75 pound weight range. This way, you can avoid the risks associated with inconsistent dosing from a broken 100mg tablet.

💡 Pro Tip: Always use the tablet size that matches your dog’s weight range to avoid complications. For dogs requiring lower doses, the 60mg tablet is a much safer option due to its scored design.


Comment 3: My dog has been on Galliprant for a while but seems more tired lately. Could this be a side effect of the medication?

Yes, lethargy can be a side effect of Galliprant, though it is less common compared to gastrointestinal symptoms like vomiting or diarrhea. In clinical studies, 6 out of 141 dogs receiving Galliprant exhibited lethargy. While this isn’t a frequent occurrence, it’s still something to monitor closely.

If your dog is showing signs of unusual tiredness or decreased energy levels, it’s important to assess how long the symptom has lasted and whether there are other side effects present, such as loss of appetite or changes in bowel movements. Lethargy could also be related to your dog’s underlying osteoarthritis pain or another health issue unrelated to Galliprant.

It’s always a good idea to check in with your veterinarian to rule out any serious issues or adjust the medication if needed. Your vet may recommend a lower dose or switching to another pain management option if the lethargy persists.

💡 Pro Tip: Keep a journal of your dog’s behavior and energy levels while on Galliprant. This can help your vet determine if the medication is still the best choice or if adjustments are needed.


Comment 4: Is it safe to give Galliprant long-term for arthritis?

Yes, Galliprant is generally safe for long-term use in managing pain and inflammation associated with osteoarthritis in dogs. One of the main advantages of Galliprant compared to traditional NSAIDs is that it targets the EP4 receptor, which specifically mediates pain and inflammation without inhibiting other prostaglandins that protect the gastrointestinal tract and kidneys. This makes it a safer option for long-term use, particularly in older dogs or those prone to gastrointestinal sensitivities.

However, long-term use of any medication requires ongoing monitoring by your veterinarian. Regular check-ups, including blood work, can help detect any early signs of organ stress or side effects, ensuring that your dog remains healthy while benefiting from the pain relief Galliprant provides.

💡 Pro Tip: To reduce potential risks, always use the lowest effective dose of Galliprant for the shortest duration possible. This strategy will help manage your dog’s pain while minimizing side effects.


Comment 5: My dog is experiencing diarrhea after starting Galliprant. Is this normal?

Yes, diarrhea is a common side effect of Galliprant, especially when starting the medication. In clinical trials, 17 out of 141 dogs treated with Galliprant experienced diarrhea or soft stool. This gastrointestinal side effect often resolves on its own as your dog’s system adjusts to the medication, but it’s important to keep an eye on the frequency and severity of the symptoms.

If your dog’s diarrhea is mild and resolves within a few days, you can continue the medication as prescribed. However, if the diarrhea persists for more than a few days, worsens, or is accompanied by other symptoms like vomiting or lethargy, it’s essential to contact your vet. Your vet may recommend adjusting the dosage, switching to a different pain management option, or providing supportive care to manage the symptoms.

💡 Pro Tip: Feed your dog a bland diet (such as boiled chicken and rice) while their gastrointestinal system recovers. Ensure they stay hydrated, as diarrhea can lead to dehydration.


Comment 6: Can I give my dog other pain medications while they are on Galliprant?

Galliprant is classified as a non-steroidal anti-inflammatory drug (NSAID), and it should not be combined with other NSAIDs like Rimadyl or Meloxicam, as this increases the risk of gastrointestinal issues, kidney damage, or other serious side effects. Similarly, Galliprant should not be combined with steroids such as prednisone or dexamethasone without veterinary guidance, as this can also increase the risk of side effects.

However, there are other pain management options that may be safely used in conjunction with Galliprant, such as gabapentin (for nerve pain) or tramadol (a mild opioid pain reliever). These medications can provide additional pain relief without the same risk of interactions, but you should always consult your veterinarian before adding any new medications to your dog’s treatment plan.

💡 Pro Tip: Always inform your vet about any supplements or medications your dog is currently taking to avoid potential drug interactions while on Galliprant.


Comment 7: My dog is still in pain after starting Galliprant. Should I increase the dose?

You should never increase the dose of Galliprant without consulting your veterinarian. The dosing guidelines are carefully calculated based on your dog’s weight to provide effective pain relief while minimizing the risk of side effects. Increasing the dose beyond the recommended amount could lead to serious health complications, including gastrointestinal ulcers, kidney issues, or liver damage.

If your dog is still in pain after starting Galliprant, speak to your vet about adjusting the treatment plan. Your vet may suggest trying a different NSAID, adding a secondary pain reliever like gabapentin, or incorporating non-medication treatments such as physical therapy or joint supplements to improve your dog’s comfort.

💡 Pro Tip: If you’re noticing little improvement in your dog’s pain levels, keep a log of their symptoms and report this to your vet. Non-drug therapies, such as weight management and low-impact exercises, can also complement your dog’s treatment plan.


Comment 8: Is Galliprant suitable for all breeds of dogs?

Galliprant is suitable for most breeds of dogs, but like any medication, it must be dosed appropriately based on weight and individual health needs. Whether your dog is a small breed, such as a Dachshund or Chihuahua, or a large breed like a Labrador or Great Dane, Galliprant can provide effective pain relief for arthritis. However, it’s important to note that Galliprant is only recommended for dogs weighing more than 8 lbs (3.6 kg), as accurate dosing cannot be achieved in smaller dogs.

For certain breeds prone to specific health issues, such as kidney or liver disease, Galliprant may require closer monitoring to ensure it’s well-tolerated. Always work with your vet to ensure that your dog’s breed-specific health concerns are taken into account when prescribing pain management medications.

💡 Pro Tip: Adjust your dog’s dosage carefully based on their current weight, and maintain regular vet visits to monitor for side effects, especially in breeds with known health risks.


Comment 9: Can Galliprant be used with joint supplements like glucosamine or fish oil?

Yes, Galliprant can be safely used alongside joint supplements such as glucosamine, chondroitin, and fish oil. In fact, these supplements can complement Galliprant’s pain-relieving effects by providing additional support for joint health and potentially helping slow the progression of osteoarthritis. While Galliprant primarily addresses the pain and inflammation associated with arthritis, joint supplements work to nourish cartilage, reduce inflammation, and improve mobility over time.

Glucosamine and chondroitin help rebuild cartilage and maintain joint fluid, while fish oil is rich in omega-3 fatty acids, which have natural anti-inflammatory properties. When used together with Galliprant, these supplements can help reduce the overall need for higher doses of pain medication as they target the condition from multiple angles.

💡 Pro Tip: Consult your vet before adding any new supplements to your dog’s regimen. Some dogs may benefit from starting these supplements early, especially those showing early signs of arthritis, as they may help delay the need for stronger medications.


Comment 10: My dog vomited after taking Galliprant. Should I stop giving it to him?

Vomiting is one of the more common side effects associated with Galliprant, and it was reported in 24 out of 141 dogs in clinical studies. While this can be concerning, vomiting is often a mild reaction that resolves after your dog’s system adjusts to the medication.

If your dog vomits after taking Galliprant, it’s not necessarily a reason to stop the medication immediately. Try administering the next dose with food to reduce the chances of stomach upset. If vomiting persists or becomes frequent, it’s important to contact your vet, who may recommend adjusting the dose or switching to a different medication.

💡 Pro Tip: To minimize gastrointestinal side effects, consider giving Galliprant with a small, bland meal (such as boiled chicken and rice) to help cushion the stomach.


Comment 11: My vet prescribed Galliprant for my dog’s arthritis, but how long before I see improvement?

You may start noticing improvements in your dog’s pain levels as soon as a few days after starting Galliprant. However, it’s important to remember that the effectiveness of the medication can vary from dog to dog. In many cases, owners report seeing increased mobility and less stiffness within the first week. For other dogs, it may take up to two weeks of consistent use to observe the full benefits of Galliprant’s anti-inflammatory effects.

If you haven’t seen improvement after two weeks or notice your dog’s pain worsening, contact your vet. It’s possible that your dog’s dosage may need adjustment, or your vet may recommend additional therapies to manage arthritis more effectively.

💡 Pro Tip: Keep a daily log of your dog’s pain and activity levels after starting Galliprant. This information will help your vet assess whether the medication is working effectively or if adjustments are needed.


Comment 12: Can I give Galliprant to my dog long-term, or should I take breaks between doses?

Galliprant is designed for long-term, consistent use in managing osteoarthritis in dogs, so there’s generally no need to take breaks between doses unless your vet advises otherwise. The medication provides continuous pain relief and inflammation control, which is essential for dogs with chronic joint conditions. Interrupting the dosage could lead to a resurgence of pain, making it harder for your dog to stay mobile and comfortable.

However, regular check-ins with your vet are crucial to ensure that your dog is tolerating the medication well over time. Periodic blood tests to monitor organ function are often recommended, especially if your dog is on other medications or has a history of kidney or liver issues.

💡 Pro Tip: Stick to the prescribed dosing schedule and keep your vet informed of any changes in your dog’s condition. If long-term use is needed, discuss the option of regular check-ups and monitoring with your vet to ensure your dog’s safety.


Comment 13: Is Galliprant better for my dog than other NSAIDs like Rimadyl or Metacam?

Galliprant offers a unique advantage over traditional NSAIDs like Rimadyl (carprofen) or Metacam (meloxicam) because it targets a specific receptor (the EP4 receptor) involved in pain and inflammation. This specificity allows Galliprant to reduce pain without affecting the production of protective prostaglandins, which help maintain the stomach lining, kidneys, and liver. As a result, Galliprant may carry fewer gastrointestinal or renal risks compared to traditional NSAIDs, making it a preferred option for dogs that are more sensitive to these side effects.

For dogs that have pre-existing kidney or liver issues, Galliprant may be safer, as it does not inhibit COX enzymes, which are typically affected by traditional NSAIDs. However, each dog responds differently to medication, so your vet will assess your dog’s specific health needs before deciding which NSAID is best suited for long-term pain management.

💡 Pro Tip: Ask your vet for periodic blood work if your dog is on any long-term NSAID, including Galliprant. This ensures your dog’s organs are functioning well while on medication and helps you stay ahead of potential side effects.


Comment 14: How does Galliprant compare to non-medication options for treating arthritis, like physical therapy?

While Galliprant is effective in controlling the pain and inflammation associated with osteoarthritis, combining it with non-medication options like physical therapy can significantly enhance your dog’s mobility and quality of life. Physical therapy, including range-of-motion exercises, hydrotherapy, and massage, can help strengthen muscles, increase joint flexibility, and reduce stiffness. These therapies work synergistically with medications like Galliprant, potentially reducing the need for higher medication doses.

Other non-medication approaches, like weight management, joint supplements, and acupuncture, can also play a key role in managing arthritis. Weight reduction, for example, lessens the load on your dog’s joints, which in turn helps alleviate pain. Meanwhile, supplements like glucosamine or fish oil can improve joint health and decrease inflammation over time.

💡 Pro Tip: Discuss with your vet about incorporating a holistic approach to your dog’s arthritis care. A combination of medication and non-medication options can provide the best results, often reducing reliance on higher doses of pharmaceuticals.


Comment 15: Can I switch from Galliprant to another NSAID if it’s not working well for my dog?

If Galliprant isn’t providing the relief your dog needs, it is possible to switch to another NSAID, but you should never do this without consulting your vet first. Switching between NSAIDs can increase the risk of gastrointestinal or renal issues, so your vet will recommend an appropriate washout period between discontinuing Galliprant and starting a new medication. This period allows your dog’s body to clear the current NSAID before introducing a new one, minimizing the risk of adverse reactions.

Your vet may recommend switching to a more traditional NSAID like Rimadyl or Meloxicam if they believe these will better address your dog’s specific needs. They may also explore combination therapy, pairing another type of medication (such as gabapentin or tramadol) with a lower dose of NSAID for enhanced pain relief without increasing the risk of side effects.

💡 Pro Tip: Work closely with your vet when adjusting any pain management plan. Keep them informed about your dog’s response to medication and ensure you follow their guidance for safe transitioning between NSAIDs.

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