Apoquel vs Zyrtec for Dogs?

Apoquel and Zyrtec are two popular options for treating itchy skin due to allergies, but how do you know which medication to choose? If you’re wondering about the differences between Apoquel vs Zyrtec for dogs, here’s a guide to help you decide.

Zyrtec vs Apoquel for Dogs

Zyrtec vs Apoquel

Apoquel and Zyrtec are both medications used to treat itching and allergic reactions in dogs.

Apoquel is a medication that is commonly used to treat itching and inflammation in dogs. It is a prescription drug that is only available through veterinarians. The active ingredient in Apoquel is oclacitinib, which is a Janus kinase (JAK) inhibitor. JAK inhibitors are a new class of drugs that target specific proteins in the immune system that are involved in inflammation and itching. Apoquel is highly effective in controlling itching and is well-tolerated by most dogs, but it can have some side effects, such as diarrhea and vomiting.

Zyrtec, on the other hand, is an antihistamine that works by blocking the action of histamine, a chemical that is responsible for causing itching, sneezing, and other symptoms of allergies. Zyrtec is less effective than Apoquel in controlling itching but can be used for treating other symptoms of allergies such as runny nose and watery eyes.

When choosing between Apoquel and Zyrtec for your dog, it’s important to consider the severity of the itching and the presence of other symptoms. If your dog has severe itching, Apoquel is likely the better choice. If your dog has more mild itching and other symptoms such as runny nose and watery eyes, Zyrtec may be a good option.

Apoquel for dogs reviews

Pros of Apoquel:

Apoquel is effective at reducing itching and inflammation in dogs. It is often used to treat allergic skin conditions such as atopic dermatitis, which is a common cause of itching in dogs.

Apoquel is fast-acting. Many dogs experience relief from itching within 4 hours of taking the medication.

Apoquel can be used in conjunction with other medications to treat underlying conditions that may be causing the itching.

Cons of Apoquel:

Apoquel is a prescription drug and is only available through veterinarians. This can be an inconvenience for some pet owners.

Apoquel has potential side effects, including vomiting, diarrhea, and decreased appetite. In rare cases, it can cause serious side effects such as liver damage.

Apoquel can be expensive, as it is a newer medication that is still under patent.

Side Effects:

Apoquel can cause side effects in some dogs, including vomiting, diarrhea, and decreased appetite. These side effects are usually mild and short-lived.

In rare cases, Apoquel can cause serious side effects such as liver damage. This is more likely to occur in dogs that have pre-existing liver conditions or are taking other medications that affect the liver.

Apoquel can also cause an increased risk of infection. This is because the medication suppresses the immune system, which can make dogs more susceptible to infections.

Toxicity:

Apoquel is considered to be safe for most dogs when used as directed. However, it should not be used in dogs that are pregnant, lactating, or have certain pre-existing conditions such as liver disease.

Apoquel should not be used in dogs that are taking certain other medications, as it can interact with these drugs and cause serious side effects.

Drug Interactions:

Apoquel can interact with certain other medications, including corticosteroids, immunosuppressants, and certain antibiotics. It is important to inform your veterinarian of any other medications your dog is taking before starting Apoquel.

Contraindications:

Apoquel is not recommended for use in dogs that are pregnant, lactating, or have certain pre-existing conditions such as liver disease.

It should not be used in dogs that are taking certain other medications, as it can interact with these drugs and cause serious side effects.

Research and Study:

Apoquel has been extensively studied in clinical trials and has been found to be effective at reducing itching and inflammation in dogs.

The safety and efficacy of Apoquel have been evaluated in several studies, and it has been found to be well-tolerated by most dogs.

Alternatives:

Some pet owners may prefer to use natural or over-the-counter alternatives to Apoquel. These can include supplements such as omega-3 fatty acids, antioxidants, and probiotics, as well as herbal remedies such as chamomile, calendula, and aloe vera.

However, it is important to note that these alternatives may not be as effective as Apoquel and may not be suitable for all dogs. Pet owners should consult with a veterinarian before using any alternative treatments.

Zyrtec for dogs reviews

Pros of Zyrtec for dogs:

Zyrtec, also known as cetirizine, is an antihistamine that is commonly used to treat allergies in dogs.

It is effective in reducing symptoms such as itching, sneezing, and runny nose.

Zyrtec is generally well-tolerated by dogs, with few reported side effects.

Cons of Zyrtec for dogs:

Zyrtec should not be used in dogs with a history of liver or kidney disease, as it can further exacerbate these conditions.

Some dogs may experience drowsiness or sedation as a side effect of Zyrtec.

It is important to note that Zyrtec should not be used in conjunction with certain medications, such as tricyclic antidepressants, as they can interact and potentially cause negative effects.

Side effects:

  • Drowsiness or sedation
  • Dry mouth
  • Loss of appetite
  • Vomiting or diarrhea

Toxicity:

Zyrtec is considered safe for use in dogs when used as directed. However, if a dog accidentally ingests a large amount of the medication, they may experience symptoms such as tremors, seizures, or coma.

Drug interactions:

Zyrtec should not be used in conjunction with tricyclic antidepressants, as they can interact and potentially cause negative effects.

It is also important to inform your veterinarian of any other medications your dog is currently taking, as Zyrtec may interact with certain drugs.

Contraindications:

Dogs with a history of liver or kidney disease should not take Zyrtec.

Research and studies:

Studies have shown that Zyrtec is effective in reducing symptoms of allergies in dogs.

Research has also found that the medication is well-tolerated by dogs, with few reported side effects.

Alternatives:

Omega-3 fatty acids and antioxidants can be used as natural alternatives to treat allergies in dogs.

OTC veterinary alternatives include diphenhydramine and loratadine. However, it is important to consult with your veterinarian before using any OTC medications for your dog.

Can dogs take Zyrtec and Apoquel together?

Dogs can take both Zyrtec and Apoquel together, as they treat different conditions.

Pros:

  • Combining these medications can provide additional relief for dogs with both allergic reactions and atopic dermatitis.
  • Zyrtec can help to reduce itching and sneezing caused by allergies, while Apoquel can help to reduce itching and inflammation caused by atopic dermatitis.

Cons:

  • Apoquel may cause side effects such as vomiting and diarrhea.
  • Zyrtec and Apoquel may interact with other medications your dog is taking, so it is important to inform your vet of all medications and supplements your dog is taking before starting treatment with these drugs.
  • Long-term use of Apoquel has been associated with an increased risk of certain types of cancer in dogs, so it is important to closely monitor your dog while they are taking this medication.

Is there an alternative to Apoquel for dogs?

Omega-3 Fatty Acids: Supplementing a dog’s diet with Omega-3 fatty acids, found in fish oil, can help reduce itching and inflammation.

Probiotics: Probiotics can improve a dog’s gut health and boost their immune system, reducing the need for anti-inflammatory drugs.

Vitamin E: Vitamin E is a powerful antioxidant that can help reduce skin irritation and improve overall skin health.

Aloe Vera: Aloe Vera has anti-inflammatory properties and can be applied topically to soothe irritated skin.

Chamomile: Chamomile has calming properties and can be used as a tea or added to a dog’s bath to reduce itching and promote relaxation.

Turmeric: Turmeric is a powerful anti-inflammatory agent and can be added to a dog’s food to improve overall health and reduce itching.

Coconut Oil: Coconut oil can be applied topically to improve skin health and reduce itching. It also has antibacterial and antifungal properties.

Licorice Root: Licorice root has anti-inflammatory properties and can be added to a dog’s food or applied topically to soothe irritated skin.

Dandelion: Dandelion has anti-inflammatory properties and can be added to a dog’s food or used as a tea to reduce itching and improve overall health.

Nettle: Nettle is a natural antihistamine and can be added to a dog’s food or used as a tea to reduce itching and improve overall health.

Conclusion of Zyrtec vs Apoquel for dogs

Zyrtec, also known as cetirizine, is an antihistamine medication commonly used to treat allergic reactions such as sneezing, itching, and runny nose. Apoquel, on the other hand, is a newer medication specifically designed for the treatment of atopic dermatitis in dogs.

Both medications have been found to be effective in reducing symptoms associated with allergies, however, Apoquel has been shown to have a more rapid onset of action and a higher degree of symptom relief compared to Zyrtec.

Zyrtec is available in tablet and liquid form and can be administered to dogs orally. Apoquel, on the other hand, is only available in tablet form and is also given orally.

Zyrtec has a relatively low risk of side effects, however, it can cause drowsiness in some dogs. Apoquel, on the other hand, has been known to cause side effects such as vomiting, diarrhea, and loss of appetite in some dogs.

Zyrtec is considered safe for long-term use, however, it is not recommended for use in dogs with liver or kidney disease. Apoquel, on the other hand, is not recommended for long-term use due to potential side effects.

Zyrtec is relatively inexpensive and can be found in most pet stores and online retailers. Apoquel, on the other hand, is a prescription medication and may be more costly.

In conclusion, both Zyrtec and Apoquel can be effective in treating allergic reactions in dogs, but they have different mechanisms of action and potential side effects. Zyrtec is a good option for mild to moderate symptoms and can be used for long-term treatment, while Apoquel is a better option for severe symptoms and should be used with caution.

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Hannah Elizabeth is an English animal behavior author, having written for several online publications. With a degree in Animal Behaviour and over a decade of practical animal husbandry experience, Hannah's articles cover everything from pet care to wildlife conservation. When she isn't creating content for blog posts, Hannah enjoys long walks with her Rottweiler cross Senna, reading fantasy novels and breeding aquarium shrimp.

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