Doxycycline Dosage for Dogs By Weight Chart

A common dosage regimen for doxycycline in dogs is 2.2 mg per pound of body weight every 12 hours, or 4.5 mg per pound of body weight every 24 hours. This means that for a dog weighing 10 pounds, the recommended dosage would be 22 mg every 12 hours, or 45 mg every 24 hours.

The exact dosage of doxycycline may vary depending on the specific condition being treated and the overall health of the dog. In some cases, a lower dosage may be recommended for dogs with liver or kidney problems.

Weight of Dog (lbs) Dosage (Every 12 hours) Dosage (Every 24 hours)
5 11 mg 22.5 mg
10 22 mg 45 mg
15 33 mg 67.5 mg
20 44 mg 90 mg
30 66 mg 135 mg
40 88 mg 180 mg
50 110 mg 225 mg
60 132 mg 270 mg
70 154 mg 315 mg
80 176 mg 360 mg
90 198 mg 405 mg
100 220 mg 450 mg

Doxycycline for dogs reviews

Doxycycline is a type of antibiotic that belongs to the tetracycline class. It is commonly used to treat a wide range of bacterial infections in dogs, including respiratory tract infections, urinary tract infections, and skin infections.


Effective against a wide range of bacterial infections

Well-tolerated by most dogs

Available in both oral and injectable forms


Can cause gastrointestinal side effects, such as nausea and diarrhea

Can cause photosensitivity, making dogs more susceptible to sunburn

Can interact with other medications, including antacids and supplements containing calcium, iron, or magnesium

Side Effects:

Gastrointestinal upset (nausea, vomiting, diarrhea)

Loss of appetite

Yeast or fungal infections


Liver and kidney problems

Development of antibiotic resistance


Doxycycline can be toxic to dogs if ingested in large amounts.

Drug Interactions:

Doxycycline can interact with other medications, including antacids and supplements containing calcium, iron, or magnesium, which can decrease its effectiveness.


Doxycycline is not recommended for use in pregnant or lactating dogs.

Should not be given to dogs with a history of liver or kidney disease.

Should not be given to dogs with a history of sensitivity to tetracycline antibiotics.

Research and Study:

Doxycycline has been extensively studied in dogs and has been shown to be effective against a wide range of bacterial infections.

However, the development of antibiotic resistance is a growing concern, and veterinarians are encouraged to use antibiotics only when necessary and to follow guidelines for appropriate use.


Some alternative options can include herbal remedies such as echinacea, goldenseal, and garlic.

Probiotics, enzymes, and other natural supplements that support the immune system can also be useful in preventing and treating infections.

It’s important to consult with a veterinarian before giving your dog any natural remedy or OTC medication.

What are the side effects of doxycycline for dogs?

Common side effects of doxycycline in dogs include:

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Nausea and vomiting: Some dogs may experience stomach upset after taking doxycycline, which can lead to nausea and vomiting.

Diarrhea: Diarrhea is another common side effect of doxycycline in dogs.

Loss of appetite: Some dogs may lose their appetite while taking doxycycline.

Yeast or fungal infections: Doxycycline can disrupt the balance of bacteria in the gut, which can lead to the overgrowth of yeast or fungal infections.

Photosensitivity: Doxycycline can cause sensitivity to sunlight, so it’s important to protect dogs from sun exposure while they’re taking the medication.

Liver and kidney damage: Long-term use of doxycycline can cause liver and kidney damage, so it is important to monitor the dog’s liver and kidney function when taking this medication.

Allergic reactions: Doxycycline can cause allergic reactions in some dogs, which can manifest as hives, itching, or difficulty breathing.

Not all dogs will experience side effects while taking doxycycline, and most side effects are relatively minor and can be managed with appropriate treatment.

How long does it take for doxycycline to work in dogs?

In general, doxycycline begins to work within the first 24-48 hours of treatment. This is when the drug starts to inhibit the growth and replication of the bacteria causing the infection. However, it can take several days or even weeks for the full therapeutic effect to be realized.

For example, in the case of Lyme disease, which is caused by the bacterium Borrelia burgdorferi, it takes about 7-14 days of treatment with doxycycline to eradicate the infection, and a treatment duration of 4-6 weeks is recommended to prevent relapse.

It’s important to note that it’s essential to complete the full course of antibiotics as prescribed by the veterinarian, even if the dog appears to be feeling better. Stopping treatment early could result in the bacteria becoming resistant to the medication and the infection returning.

Also, the efficacy of the medication can be affected by factors such as the dog’s overall health, underlying medical conditions, and concurrent medications. Therefore, it is essential to follow the veterinarian’s instructions and keep all follow-up appointments to monitor your dog’s response to the medication.

Is human and dog doxycycline the same?

Doxycycline is a type of antibiotic that is commonly used to treat a variety of bacterial infections in both humans and dogs. While the medication may be prescribed for similar conditions in both species, it is important to note that the dosage and administration of doxycycline for dogs may differ from that of humans.

Can a dog overdose on doxycycline?

According to the Merck Veterinary Manual, the standard recommended dosage for doxycycline in dogs is 2.2-4.5mg/lb orally every 12-24 hours. It is important to follow the dosage instructions provided by the veterinarian and not exceed the recommended amount.

Symptoms of doxycycline overdose in dogs may include vomiting, diarrhea, loss of appetite, and lethargy. In severe cases, the dog may experience central nervous system depression, which can lead to seizures and even death.

Doxycycline should not be used in dogs with a history of liver or kidney disease, as these conditions may increase the risk of overdose. Additionally, doxycycline should not be used in combination with other tetracycline antibiotics as this can also increase the risk of overdose.

Doxycycline for dogs without a vet prescription

One option for purchasing doxycycline for dogs without a prescription is through online pet pharmacies. These pharmacies often require a valid prescription from a veterinarian, but there are some that do not. It’s important to do research and read reviews on the online pet pharmacy before making a purchase to ensure that it is legitimate and reliable.

Another option is to purchase doxycycline for fish and use it for your dog as it is chemically the same. It is important to be aware that the dosage and administration may be different for dogs and fish and should consult with a veterinarian before administering.

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Lastly, some feed and agricultural supply stores may carry Doxycycline for use in livestock, which can also be used for dogs. It is important to check the dosage and ensure that the medication is safe for use in dogs before administering it.

Doxycycline is a prescription medication and should only be used under the guidance of a veterinarian. Self-diagnosis and treatment can be dangerous for your dog and may lead to further health complications. It is always best to consult with a veterinarian before administering any medication to your dog.

FAQs about doxycycline for dogs

What is Doxycycline for Dogs?

Doxycycline is an antibiotic that is often prescribed to dogs to treat a variety of bacterial infections. It is a broad-spectrum antibiotic that belongs to the tetracycline family. In simple terms, it means that doxycycline can kill a wide range of bacteria that may cause infections in dogs.

When is Doxycycline Prescribed for Dogs?

Doxycycline is prescribed for dogs to treat a variety of infections. Some common conditions that may require doxycycline treatment include:

  • Respiratory infections, such as kennel cough and pneumonia
  • Tick-borne illnesses, such as Lyme disease, Rocky Mountain spotted fever, and ehrlichiosis
  • Urinary tract infections
  • Skin infections, such as pyoderma and dermatitis
  • Gastrointestinal infections, such as diarrhea and vomiting

What is the Dosage of Doxycycline for Dogs?

The dosage of doxycycline for dogs depends on several factors, including the dog’s weight, age, and overall health. Typically, the recommended dosage is 5-10 mg/kg of body weight, given orally twice a day. However, it is important to follow the specific instructions provided by the veterinarian, as the dosage may vary based on the condition being treated.

What are the Side Effects of Doxycycline for Dogs?

Like any medication, doxycycline can cause side effects in dogs. Some common side effects include:

  • Upset stomach, vomiting, and diarrhea
  • Loss of appetite
  • Sun sensitivity (dogs may develop a rash or sunburn if exposed to sunlight)
  • Tooth discoloration (this is more common in young puppies)
  • Difficulty swallowing (in rare cases)

If you notice any of these side effects, you should contact your veterinarian immediately.

Can Doxycycline be Given to Pregnant or Nursing Dogs?

Doxycycline is generally not recommended for pregnant or nursing dogs, as it may affect the development of the puppies. However, in some cases, the benefits of using doxycycline may outweigh the risks. It is important to discuss the potential risks and benefits with your veterinarian before giving doxycycline to a pregnant or nursing dog.

How Should Doxycycline be Stored?

Doxycycline should be stored in a cool, dry place, away from direct sunlight and heat. It should also be kept out of reach of children and pets. Additionally, it is important to check the expiration date before giving doxycycline to your dog, as expired medication may not be effective and could potentially harm your dog.

Can I Give My Dog Doxycycline for a Human?

No, you should never give your dog medication that is meant for humans without consulting a veterinarian. Medications that are safe for humans may not be safe for dogs, and the dosage may be different. Giving your dog doxycycline or any other medication without proper veterinary guidance could potentially harm your dog.

How Should Doxycycline be Administered to Dogs?

Doxycycline is typically administered orally in the form of tablets or capsules. It can be given with or without food, but it is generally recommended to give it with food to reduce the risk of an upset stomach. If your dog has difficulty swallowing the medication, you can try hiding it in a piece of cheese or meat to make it easier to swallow.

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It is important to give the full course of medication, even if your dog’s symptoms improve. Failure to complete the full course of antibiotics can lead to the development of antibiotic-resistant bacteria, which can be difficult to treat.

How Long Does it Take for Doxycycline to Work in Dogs?

The time it takes for doxycycline to work in dogs varies depending on the condition being treated. In some cases, you may see improvement in your dog’s symptoms within a few days of starting the medication. However, in other cases, it may take several weeks before you see improvement.

It is important to follow the full course of medication as prescribed by your veterinarian, even if your dog’s symptoms improve. If you stop giving the medication prematurely, the infection may return, and it may be more difficult to treat the second time around.

Are There any Precautions to Take When Giving Doxycycline to Dogs?

Yes, there are some precautions you should take when giving doxycycline to dogs. Some important things to keep in mind include:

  • Do not give doxycycline to dogs that are allergic to tetracycline antibiotics
  • Do not give doxycycline to dogs with liver or kidney disease, as it may exacerbate these conditions
  • Do not give doxycycline to dogs that are pregnant or nursing without first consulting with a veterinarian
  • Do not give doxycycline to puppies under six months of age, as it can interfere with the development of their teeth and bones
  • Be sure to follow your veterinarian’s instructions carefully, and never give your dog more or less medication than prescribed

Can Doxycycline Interact with Other Medications?

Yes, doxycycline can interact with other medications, including antacids, calcium supplements, and certain antibiotics. It is important to let your veterinarian know about all medications and supplements your dog is taking before starting doxycycline. Your veterinarian can advise you on whether any adjustments need to be made to the dosages or schedules of your dog’s medications.

What Should I Do if I Miss a Dose of Doxycycline for My Dog?

If you miss a dose of doxycycline for your dog, you should give it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and resume the regular dosing schedule. Do not give your dog two doses at once, as this can increase the risk of side effects.

If you miss more than one dose of doxycycline, contact your veterinarian for advice on how to proceed.

How Does Doxycycline Treat Infections in Dogs?

Doxycycline is a type of antibiotic that works by preventing the growth and spread of bacteria in the body. It does this by inhibiting the ability of bacteria to produce proteins, which they need to survive and replicate. By disrupting the bacteria’s ability to produce proteins, doxycycline effectively stops the infection from spreading and allows the dog’s immune system to fight off the bacteria.

Can Doxycycline be Used to Treat Heartworm Disease in Dogs?

Yes, doxycycline is often used in conjunction with other medications to treat heartworm disease in dogs. While doxycycline does not directly kill the heartworms, it is believed to weaken the worms and make them more susceptible to other medications. By weakening the worms, doxycycline can also reduce the severity of the dog’s symptoms during treatment.

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