Trazodone for Dogs Dosage By Weight

Trazodone is a medication that is often prescribed to dogs to help manage anxiety, stress, and behavioral issues. As a pet owner, it’s essential to understand the proper dosage of trazodone for your furry friend. This guide provides a comprehensive trazodone dosage chart based on your dog’s weight, along with helpful tips and precautions to ensure the safe use of this medication.

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Trazodone for dogs dosage chart (50mg, 100mg)

What is Trazodone?

Trazodone is a serotonin antagonist and reuptake inhibitor (SARI) that works by increasing the availability of serotonin in the brain. This helps to regulate mood and alleviate anxiety-related symptoms in dogs.

Why is Trazodone prescribed for dogs?

Trazodone is often prescribed for dogs that suffer from anxiety, stress, or behavioral problems. It can also be used to help dogs cope with specific situations, such as travel, thunderstorms, or visits to the vet.

Trazodone Dosage Chart by Dog Weight

Use the following trazodone dosage chart as a starting point to determine the appropriate dosage for your dog. Remember, it’s crucial to consult with your veterinarian before administering trazodone or adjusting the dosage.

  • 10 lbs: 9 to 43 mg
  • 20 lbs: 18 to 86 mg
  • 30 lbs: 27 to 129 mg
  • 40 lbs: 36 to 172 mg
  • 50 lbs: 45 to 215 mg
  • 60 lbs: 54 to 258 mg
  • 70 lbs: 63 to 301 mg
  • 80 lbs: 72 to 344 mg
  • 90 lbs: 81 to 387 mg
  • 100 lbs: 90 to 430 mg

Starting with a Low Dose

Begin with a low dose of 0.9 to 1.36 mg per pound of body weight, given every 24 hours. Gradually increase the dosage as needed, under the guidance of your veterinarian.

Combining Trazodone with Other Medications

If your dog is taking other medications, lower doses of trazodone may be sufficient. Always consult your veterinarian before combining trazodone with any other medications to avoid potential drug interactions.

Is there an alternative to trazodone for dogs?

If you’re looking for a natural way to help calm your furry friend, here are some alternatives to trazodone that are worth considering.

1. Hemp Oil for Dogs: A Natural and Safe Option

Hemp oil, also known as CBD oil, is a natural and safe option that can be used to reduce anxiety and promote overall well-being for your dog. It’s derived from the hemp plant and contains only a trace amount of THC, which means it doesn’t have any psychoactive effects. Hemp oil can be given as a supplement or added to your dog’s food.

2. Rescue Remedy for Dogs: A Blend of Flower Essences

Rescue Remedy is a natural remedy made from a blend of five flower essences that is designed to calm nervous dogs during stressful situations. It can be given as drops, sprayed onto their tongue, or added to their water bowl.

3. ThunderEase Dog Calming Pheromone Diffuser: Mimics a Mother’s Scent

ThunderEase diffuser mimics the pheromones produced by a mother dog to calm and soothe puppies. It can be used to help dogs with separation anxiety or fear of loud noises. The diffuser can be plugged in anywhere in your home, and the calming scent will fill the room.

4. Adaptil Calm Home Diffuser: A Safe Alternative

Adaptil Calm Home Diffuser is a natural alternative that helps to calm dogs during stressful situations by mimicking the pheromones produced by a mother dog. The diffuser is easy to use and can be plugged into any outlet in your home.

5. Zesty Paws Calming Bites: Delicious and Effective

Zesty Paws Calming Bites are chews that contain natural ingredients like chamomile and passionflower to help soothe anxious dogs and promote relaxation. They’re also delicious, making them a great option for picky eaters.

6. Adaptil Calming Collar: A Safe and Effective Solution

Adaptil Calming Collar is another natural alternative that releases a gentle, comforting scent that helps to soothe your pet and reduce anxiety. The collar can be worn all day and is a safe and effective solution for anxious dogs.

7. Thundershirt: A Comforting Wrap

Thundershirt is a calming wrap made with a special material that mimics the comforting sensation of being in a mother’s embrace. It provides a gentle, constant pressure that can help calm anxious dogs during stressful situations.

FAQs about trazodone for dogs

Here are some frequently asked questions and their answers regarding trazodone for dogs:

What is Trazodone, and How Does it Work in Dogs?

Trazodone is a prescription medication primarily used to treat depression in humans. However, veterinarians have discovered its benefits in treating behavioral issues in dogs as well. The drug works by increasing the levels of serotonin in the brain, which helps promote a sense of calm and well-being.

Why Might a Dog be Prescribed Trazodone?

Trazodone is often prescribed for dogs experiencing anxiety, fear, or stress-related behaviors. Common scenarios include separation anxiety, noise phobias (like thunderstorms or fireworks), and situational anxiety during vet visits or grooming sessions. Additionally, it may be used to help dogs with sleep disturbances or as a mild sedative before a medical procedure.

Is Trazodone Safe for My Dog?

While trazodone is generally considered safe for dogs when prescribed by a veterinarian, it’s crucial to follow their guidelines and dosing recommendations. Side effects are usually mild and may include drowsiness, gastrointestinal issues, or increased thirst. However, if you notice any severe reactions or symptoms that don’t improve, contact your veterinarian right away.

How Long Does Trazodone Take to Work on Dogs?

The onset of trazodone’s effects varies between dogs, but generally, you can expect to see improvement in your pet’s behavior within 1-2 hours after administration. The drug’s duration of action typically ranges from 8-12 hours, but individual factors like the dog’s size, metabolism, and the specific issue being treated can impact this timeline.

Can Trazodone be Given with Other Medications?

In many cases, trazodone can be safely combined with other medications to provide a more comprehensive treatment plan for your dog. However, it’s essential to discuss your pet’s medical history and current medications with your veterinarian to avoid potential drug interactions or side effects.

How Should I Administer Trazodone to My Dog?

Trazodone comes in tablet form and can be given with or without food. Follow your veterinarian’s instructions for dosage and frequency, and be sure to administer the medication consistently to ensure its effectiveness. If you miss a dose, give it as soon as you remember, but don’t double up on doses to avoid potential side effects.

Can My Dog Become Dependent on Trazodone?

Trazodone is not considered to be habit-forming or addictive. However, if your dog has been on the medication for an extended period, consult your veterinarian before stopping treatment, as they may need to gradually taper the dosage to avoid potential withdrawal symptoms.

What Should I Do If My Dog Experiences Side Effects from Trazodone?

If your dog experiences mild side effects such as drowsiness or mild gastrointestinal issues, it’s usually not a cause for alarm. However, if the side effects become severe or persistent, contact your veterinarian immediately. They may need to adjust the dosage or consider alternative treatments to ensure your pet’s well-being.

Can Trazodone Cause Weight Gain in Dogs?

Weight gain is not a common side effect of trazodone in dogs. However, individual reactions may vary. Monitor your dog’s weight and appetite while on the medication, and discuss any concerns with your veterinarian to ensure your pet maintains a healthy weight.

Is Trazodone Safe for Senior Dogs?

Trazodone can be safe for senior dogs, but it’s essential to consult with your veterinarian before starting any new medication. Older dogs may have age-related health issues or be on other medications, which could impact the safety and effectiveness of trazodone. Your vet will consider your dog’s overall health and may recommend a lower dosage or additional monitoring.

How Should I Store Trazodone?

Store trazodone in a cool, dry place away from direct sunlight and out of reach of children and pets. Make sure to keep the medication in its original container with a tight-fitting lid to maintain its potency and prevent accidental ingestion.

Can Trazodone be Used for Cats as Well?

While trazodone is primarily used in dogs, it can also be prescribed for cats in certain situations, such as to manage anxiety or stress-related behaviors. However, the dosage and administration may differ, so consult your veterinarian before giving your cat trazodone.

Is Trazodone a Long-term Solution for My Dog’s Anxiety?

Trazodone can be used for short-term or long-term treatment, depending on the severity and nature of your dog’s anxiety. In some cases, it may be used as a temporary solution during specific events, while in others, it may be prescribed as part of a long-term management plan. Always consult your veterinarian to determine the best course of action for your pet.

What Alternatives are Available if Trazodone Isn’t Suitable for My Dog?

If trazodone isn’t the right fit for your dog, several other medications, therapies, and techniques can help manage anxiety and stress-related behaviors. Some alternatives include other prescription medications like fluoxetine, clomipramine, or alprazolam, as well as natural supplements, pheromone products, and behavioral modification techniques. Talk to your veterinarian to explore the best options for your dog’s specific needs.

How Do I Handle an Overdose of Trazodone in My Dog?

If you suspect your dog has accidentally ingested too much trazodone, seek immediate veterinary attention. Signs of an overdose may include severe drowsiness, vomiting, tremors, increased heart rate, or difficulty breathing. Prompt treatment is crucial to prevent potential complications and ensure your dog’s safety.

Can I Use Trazodone for My Dog’s Aggression Issues?

Trazodone is primarily used to treat anxiety and stress-related behaviors in dogs. While it may help manage aggression stemming from anxiety, it’s not specifically designed to address aggression issues. If your dog displays aggressive behavior, consult your veterinarian for a tailored treatment plan, which may include behavioral modification, training, or other medications.

What if My Dog is Pregnant or Nursing? Can She Take Trazodone?

The safety of trazodone in pregnant or nursing dogs hasn’t been extensively studied. As a precaution, it’s essential to consult your veterinarian before giving trazodone to a pregnant or nursing dog. They will weigh the potential risks and benefits to determine the best course of action for your pet.

Are There Any Breeds That Should Avoid Trazodone?

Trazodone is generally safe for most dog breeds when prescribed by a veterinarian. However, individual dogs may have unique health concerns or genetic predispositions that could affect their response to the medication. Always consult your veterinarian to ensure trazodone is suitable for your specific dog.

What Happens if Trazodone Doesn’t Work for My Dog?

If trazodone doesn’t seem to be effective in managing your dog’s anxiety or stress-related behaviors, don’t hesitate to discuss your concerns with your veterinarian. They may recommend adjusting the dosage, trying a different medication, or incorporating other treatment options like behavioral therapy, training, or natural remedies.

Can Trazodone Interact with Supplements or Over-the-Counter Medications?

Trazodone may interact with certain supplements or over-the-counter medications. It’s crucial to inform your veterinarian about any supplements or over-the-counter medications your dog is taking to avoid potential interactions or adverse effects.

How Do I Wean My Dog Off Trazodone Safely?

If your veterinarian recommends discontinuing trazodone, it’s essential to follow their guidance for tapering the medication. Gradually reducing the dosage over time can help minimize potential withdrawal symptoms and ensure a smooth transition for your pet.


Hannah Elizabeth is an English animal behavior author, having written for several online publications. With a degree in Animal Behaviour and over a decade of practical animal husbandry experience, Hannah's articles cover everything from pet care to wildlife conservation. When she isn't creating content for blog posts, Hannah enjoys long walks with her Rottweiler cross Senna, reading fantasy novels and breeding aquarium shrimp.

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