Vetmedin Dosing Chart

VETMEDIN® (pimobendan) Chewable Tablets:

Indications: Management of symptoms of mild, moderate, or severe congestive heart failure (CHF) in dogs caused by MMVD or DCM.

Dosage & Administration:

  • Total daily dose: 0.23mg/lb (0.5 mg/kg) body weight.
  • The total dose should be divided into two portions approximately 12 hours apart (morning and evening).
  • The tablets are scored, and dosage should be given to the nearest half-tablet increment.
Tablet Size Body Weight Total Daily Dosage Bottle Duration Morning Evening
1.25 mg 2.5 kg/5.5 lb 1.25 mg 50 days 1/2 💊 1/2 💊
3.75 kg/8.3 lb 1.875 mg 33 days 1 💊 1/2 💊
2.5 mg 5 kg/11 lb 2.5 mg 50 days 1/2 💊 1/2 💊
7.5 kg/16.5 lb 3.75 mg 33 days 1 💊 1/2 💊
5.0 mg 10 kg/22 lb 5 mg 50 days 1/2 💊 1/2 💊
15 kg/33 lb 7.5 mg 33 days 1 💊 1/2 💊
20 kg/44 lb 10 mg 25 days 1 💊 1 💊
10 mg 30 kg/66 lb 15 mg 33 days 1 💊 1/2 💊
40 kg/88 lb 20 mg 25 days 1 💊 1 💊

Clinical Benefits: VETMEDIN tablets have shown to increase survival times in dogs and improve their quality of life after a CHF diagnosis.

Safety: VETMEDIN has a dual mode of action, relaxing blood vessels and improving heart muscle function.

Common Heart Conditions in Dogs:

  • Myxomatous Mitral Valve Disease (MMVD): A condition where the degeneration of the mitral valve leads to blood leakage back into the left atrium. It accounts for approximately 75% of canine heart diseases.
  • Dilated Cardiomyopathy (DCM): A condition where heart muscles are weakened, causing reduced contraction force. It accounts for about 10% of acquired canine heart disease.

VETMEDIN vs. Compounded Pimobendan:

  • VETMEDIN is FDA-approved for treating CHF in dogs.
  • Compounded preparations are not evaluated by the FDA for safety and are not equivalent to generic drug products.

Unique Action: VETMEDIN acts as both a positive inotrope and a potent vasodilator, dilating veins and arteries. It ensures optimal therapeutic effect and bioavailability.

Contraindications: Not recommended for dogs with hypertrophic cardiomyopathy, aortic stenosis, or any condition where augmentation of cardiac output is inappropriate.


  • Only for dogs with clinical evidence of heart failure.
  • Prolonged use at 3-5 times the recommended dose can cause cardiac issues.
  • Not for human use.

Precautions: Safety hasn’t been established in dogs with asymptomatic heart disease, dogs younger than 6 months, dogs with certain other health conditions, or pregnant/lactating bitches.

Adverse Reactions: Some side effects were reported in field studies.

Always consult with a veterinarian before administering medication to ensure the right dosage and to be aware of any potential side effects or interactions.

What Makes Vetmedin Unique?

Vetmedin (pimobendan) is not just another medication; it’s a beacon of hope for dogs grappling with CHF. Unlike conventional treatments, Vetmedin adopts a dual-action approach, simultaneously relaxing blood vessels and enhancing heart muscle function. This powerful combination ensures a more efficient heart, translating to extended survival times and a noticeable boost in life quality post-CHF diagnosis.

Key Takeaway: Vetmedin is a game-changer, offering a unique dual-action formula that promises a brighter, healthier future for dogs with CHF.

Comparing Vetmedin: A Clinical Victory

When pitted against ACE inhibitors, another common CHF treatment, Vetmedin’s prowess becomes evident. Dogs receiving Vetmedin not only lived nearly twice as long but also required less additional therapy to maintain their life quality. This isn’t just a win; it’s a clinical victory for Vetmedin.

Key Takeaway: Choose Vetmedin for unparalleled efficacy, ensuring your furry friend not only lives longer but also enjoys a higher quality of life.

Early Detection: The Power to Change the Course

Recognizing the early signs of CHF can make a world of difference. The American College of Veterinary Internal Medicine (ACVIM) urges pet owners and vets to be vigilant, watching out for symptoms like rapid breathing, persistent coughing, and reluctance to exercise. Catching CHF early opens the door to timely intervention, potentially transforming the disease’s trajectory.

Key Takeaway: Stay alert to the early signs of CHF. Early detection and intervention are key to ensuring the best possible outcome for your pet.

At-Risk Breeds: Know Your Dog’s Heart

Different heart conditions leading to CHF tend to affect specific dog sizes. Large breeds are more prone to Dilated Cardiomyopathy (DCM), while smaller breeds often grapple with Myxomatous Mitral Valve Disease (MMVD). Knowing your dog’s risk based on their breed ensures a proactive approach to their heart health.

MMVD: A Small Dog’s Battle

Common among small and medium-sized breeds, MMVD is a chronic condition where the mitral valve degenerates, hindering proper blood flow.

At-Risk Breeds:

  • Cavalier King Charles Spaniel
  • Pekingese
  • Pomeranian …and others.

DCM: The Large Dog’s Dilemma

DCM weakens the heart muscles, reducing the heart’s pumping strength, a condition more prevalent in larger dog breeds.

At-Risk Breeds:

  • Doberman Pinscher
  • Great Dane
  • Boxer …and others.

Key Takeaway: Awareness of your dog’s breed-specific risks empowers you to take proactive steps in safeguarding their heart health.

Vetmedin Vs. Compounded Pimobendan: The Unmatched Champion

Vetmedin stands as the only FDA-approved product for treating CHF in dogs, a testament to its safety and efficacy. Compounded pimobendan formulations, lacking FDA evaluation and bioequivalence, simply can’t match up. Vetmedin’s proprietary formula ensures optimal absorption and therapeutic effect, making it the unrivaled choice for canine CHF treatment.

Key Takeaway: Trust Vetmedin for its FDA-approved status and unmatched efficacy, ensuring your dog receives the best possible care.

Contraindications and Precautions: Vetmedin’s Safety Profile

While Vetmedin is a lifesaver for many, it’s not suitable for all. Dogs with certain cardiac conditions, such as hypertrophic cardiomyopathy or aortic stenosis, should avoid Vetmedin. Likewise, its safety remains unestablished in asymptomatic heart disease, puppies under 6 months, and dogs with congenital heart defects or serious metabolic diseases.

Key Takeaway: Vetmedin is a powerful medication with a strong safety profile, but it’s crucial to consult with your veterinarian to ensure it’s the right choice for your furry friend.

The Vetmedin Experience: A Tail Wagging Transformation

From improving survival times to enhancing life quality, Vetmedin is transforming lives across the canine world. Its unique action, unmatched efficacy, and broad recommendation from veterinary professionals make it a standout choice for managing CHF.

Vetmedin Journey: A Quick Glance

Feature Vetmedin Other Treatments
Dual-Action Formula
Improved Survival Times
Enhanced Life Quality
Reduced Need for Additional Therapy
Recommended by ACVIM
Highly Palatable

Key Takeaway: Vetmedin is not just a medication; it’s a transformative experience for dogs with CHF, offering unparalleled benefits and a brighter future.

In Conclusion: A Heartfelt Recommendation

Vetmedin stands tall as a beacon of hope in canine cardiac care, offering a unique, dual-action formula that promises extended survival and improved life quality for dogs with CHF. Its unmatched efficacy, broad professional recommendation, and proven safety profile make it the go-to choice for pet owners and veterinary professionals alike. With Vetmedin, we’re not just treating symptoms; we’re unlocking longer, happier lives for our four-legged friends.

FAQs: Vetmedin

What Exactly is Vetmedin and How Does it Work?

Vetmedin is a chewable tablet containing pimobendan as its active ingredient. It functions uniquely by opening up the blood vessels leading to and from the heart, reducing the workload on your dog’s heart. Additionally, it strengthens the heart muscle’s contractions, making each heartbeat more efficient in pumping blood. This two-pronged action culminates in a significant enhancement in your pet’s heart function and overall well-being.

How Quickly Does Vetmedin Start Working?

Vetmedin is known for its rapid action. Once administered, it gets absorbed quickly from the digestive tract, making its way into the bloodstream. Most pet owners report observing noticeable improvements in their dog’s energy levels, breathing, and exercise tolerance within a week of starting Vetmedin.

Can Vetmedin Be Given Alongside Other Medications?

Yes, Vetmedin is often prescribed in conjunction with other medications such as diuretics, ACE inhibitors, or beta-blockers. However, it’s crucial to follow your veterinarian’s guidance closely to ensure all medications work harmoniously and to monitor for any potential interactions.

Are There Any Side Effects of Vetmedin?

While Vetmedin is generally well-tolerated by dogs, some may experience side effects. Common ones include loss of appetite, diarrhea, and lethargy. In rare cases, more severe reactions can occur. It’s imperative to monitor your dog closely when starting a new medication and report any unusual symptoms to your veterinarian immediately.

How Is Vetmedin Different from Other CHF Medications?

Vetmedin’s unique mode of action sets it apart. Unlike other medications that only address one aspect of heart function, Vetmedin works simultaneously as a vasodilator and a positive inotrope. This dual-action not only improves the efficiency of the heart but also reduces the strain on it, leading to improved survival times and life quality.

Can All Dogs Take Vetmedin?

Vetmedin is safe for most dogs diagnosed with CHF. However, it’s not suitable for dogs with certain types of heart disease where increasing the heart’s output is not advisable, nor is it recommended for dogs with asymptomatic heart disease. It’s essential to have a thorough veterinary evaluation to determine if Vetmedin is the right choice for your pet.

What Should I Do If I Miss a Dose?

If you miss giving your dog a dose of Vetmedin, give it as soon as you remember. However, if it’s almost time for the next scheduled dose, skip the missed dose and continue with the regular dosing schedule. Avoid doubling up on doses, as this could lead to an overdose.

Can Vetmedin Cure My Dog’s Heart Condition?

While Vetmedin significantly improves the quality of life and survival times in dogs with CHF, it is not a cure for heart disease. It works to manage the symptoms and slow the progression of the disease, helping your dog live a fuller, more comfortable life.

How Should Vetmedin Be Stored?

Vetmedin should be stored in a cool, dry place, away from direct sunlight and out of reach of children and pets. Ensure the cap is tightly closed to maintain the medication’s efficacy.

Is There a Specific Time of Day When Vetmedin Should Be Administered?

Vetmedin can be given at any time of the day, but it’s important to be consistent with the timing. Ideally, the medication should be administered approximately one hour before feeding to ensure optimal absorption. Discuss with your veterinarian to establish a dosing schedule that suits your dog’s specific needs.

How Long Does a Dog Typically Stay on Vetmedin?

When a veterinarian prescribes Vetmedin, it is usually a lifelong commitment. The medication addresses the symptoms of congestive heart failure and improves the dog’s quality of life, but it does not cure the disease. Regular check-ups are crucial to monitor the dog’s condition and adjust the treatment plan as necessary.

Is Vetmedin Suitable for Dogs of All Ages?

Vetmedin has not been extensively studied in dogs younger than 6 months or in pregnant or lactating females. For these groups of dogs, a veterinarian will carefully weigh the benefits against the potential risks before prescribing Vetmedin.

What Should I Do if My Dog Shows Adverse Reactions to Vetmedin?

If you notice any signs of an adverse reaction, such as persistent lethargy, difficulty breathing, or gastrointestinal upset, contact your veterinarian immediately. In some cases, the dosage may need to be adjusted, or an alternative treatment may be considered.

How Does Vetmedin Compare to Compounded Pimobendan?

Vetmedin is the only FDA-approved pimobendan product, ensuring consistent quality and efficacy. Compounded pimobendan preparations have not undergone the rigorous testing required for FDA approval, and their safety and efficacy can vary significantly. Using Vetmedin ensures your dog receives a consistent and reliable dose of medication.

Can Vetmedin Interact with Other Medications My Dog Is Taking?

While Vetmedin is safe to use with many other medications, interactions can occur. Always inform your veterinarian about all medications and supplements your dog is taking to prevent potential interactions.

What Role Does Vetmedin Play in Treating Different Stages of CHF?

Vetmedin is effective in managing symptoms in mild, moderate, and severe cases of CHF due to MMVD or DCM. It plays a crucial role in improving the dog’s quality of life and survival time, regardless of the disease stage.

Does Vetmedin Have Any Impact on My Dog’s Energy Levels?

Many pet owners report a noticeable increase in energy and activity levels in their dogs after starting Vetmedin. This is likely due to the improved heart function and blood flow, allowing the dog to feel more energetic and lively.

How Can I Ensure My Dog Takes the Vetmedin Tablet?

Vetmedin tablets are beef-flavored to enhance palatability, making it easier for pet owners to administer. You can give the tablet directly or hide it in a small treat or piece of food to ensure your dog takes the medication.

Is There a Specific Diet My Dog Should Follow While on Vetmedin?

There is no specific diet required for dogs on Vetmedin, but a balanced and nutritious diet can help support their overall health. Your veterinarian can provide guidance on the best diet for your dog’s condition.

What Research Supports the Use of Vetmedin in Dogs with CHF?

Numerous clinical studies have demonstrated Vetmedin’s effectiveness in increasing survival times and improving the quality of life in dogs with CHF. It has been shown to be superior to other treatments, such as ACE inhibitors, particularly when administered at the onset of clinical signs.


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