Apoquel vs Benadryl for Dogs?

Apoquel is a newer medication specifically designed to treat skin allergies in dogs, while Benadryl is a more versatile drug that can be used for a wider range of issues, including allergies and allergic reactions, motion sickness, insomnia, and more. Apoquel starts to work much faster, usually within 4 hours, while Benadryl usually takes 30 minutes to an hour to take effect. However, both medications have potential side effects, and it’s important to talk to your veterinarian before starting any new medication for your dog.

Feature	Apoquel	Benadryl
Purpose	Treats atopic dermatitis (skin allergies)	Treats allergies and allergic reactions, as well as motion sickness, insomnia, and more
Active Ingredient	Oclacitinib	Diphenhydramine
Dosage	Given once daily	Given every 8-12 hours
Time to Take Effect	Typically within 4 hours	Typically within 30 minutes to 1 hour
Possible Side Effects	Loss of appetite, vomiting, diarrhea	Drowsiness, dry mouth, and loss of appetite
Precautions	Should not be used in breeding, pregnant or lactating dogs	Should not be used in dogs with glaucoma, high blood pressure, or prostate enlargement

Apoquel and Benadryl together for dogs

Can Apoquel and Benadryl be used together? The answer is yes, but it’s always best to check with your veterinarian first. They will be able to give you the best advice on whether it’s safe for your furry friend and the proper dosages to use.

In some cases, using both Apoquel and Benadryl together can be a double whammy for dogs with itchy skin and allergies. The combination can help relieve itching and inflammation more effectively than just using one of the drugs alone. It’s like killing two birds with one stone.

But, as with any medication, there are also potential side effects to be aware of. Some dogs may experience drowsiness, dry mouth, and constipation when taking Benadryl. So, it’s important to keep an eye on your pup and make sure they’re not feeling any adverse reactions.

Benadryl for dogs reviews

Pros:

Benadryl is a commonly used antihistamine that can help alleviate symptoms of allergies, such as itching, sneezing, and runny nose.

It is also used to treat anxiety and motion sickness in dogs.

Benadryl is generally safe and well-tolerated by dogs and is available over the counter.

Cons:

Some dogs may experience drowsiness or sedation as a side effect of taking Benadryl.

The dosage recommended for dogs may be different from the dosage for humans, so it is important to follow your veterinarian’s instructions carefully.

Long-term use of Benadryl can result in a dependency on the drug and should be avoided if possible.

Side Effects:

Common side effects of Benadryl in dogs include drowsiness, dry mouth, and gastrointestinal upset.

In rare cases, Benadryl can cause more serious side effects such as difficulty breathing, loss of appetite, and tremors.

If you notice any concerning side effects, contact your veterinarian immediately.

Toxicity:

Benadryl is considered safe for use in dogs when used as directed.

However, an overdose of Benadryl can be harmful and potentially fatal.

Keep the medication out of reach of children and pets and follow your veterinarian’s dosage instructions closely.

Drug Interactions:

Benadryl can interact with other medications, particularly those that also cause drowsiness.

Be sure to inform your veterinarian of any other medications your dog is currently taking before starting treatment with Benadryl.

Contraindications:

Benadryl should not be used in dogs with a history of heart disease or hypertension.

It should also be avoided in dogs that are pregnant or lactating.

Research and Study:

There have been a number of studies on the safety and efficacy of Benadryl in dogs.

A study published in the Journal of the American Veterinary Medical Association found that Benadryl was effective in reducing symptoms of allergic reactions in dogs.

Another study published in the Journal of Veterinary Pharmacology and Therapeutics found that Benadryl was effective in reducing symptoms of motion sickness in dogs.

Apoquel for dogs reviews

Pros:

Apoquel is a highly effective treatment for atopic dermatitis, a common skin condition characterized by itching, redness, and inflammation. It works by blocking certain chemical receptors in the body that contribute to the symptoms of the condition.

Apoquel starts to work quickly, with many dogs experiencing significant improvement in their symptoms within 24-48 hours of starting treatment.

The drug is available in tablet form and is easy to administer to dogs.

Cons:

Apoquel is a relatively new drug and there are still many unknowns about its long-term safety and effectiveness. Some experts recommend using it only as a last resort after other treatment options have failed.

The drug can have serious side effects, including an increased risk of infection, increased risk of cancer, and increased risk of liver damage.

Apoquel can interact with other medications, so it is important to inform your vet of all medications your dog is taking before starting treatment with Apoquel.

Side Effects:

Some of the most common side effects of Apoquel include increased appetite, increased thirst, and increased urination.

More serious side effects include diarrhea, vomiting, loss of appetite, and decreased activity levels.

In rare cases, Apoquel can cause serious side effects like organ damage and cancer.

Toxicity:

Apoquel is not considered toxic when used at the recommended dosage.

However, if your dog accidentally ingests too much of the drug, it can cause serious side effects.

Drug Interactions:

Apoquel can interact with other medications, including antibiotics, anti-inflammatory drugs, and steroidal medications.

Always inform your vet of all medications your dog is taking before starting treatment with Apoquel.

Contraindications:

Apoquel is not recommended for dogs with certain health conditions, including cancer, liver disease, and immune-mediated disorders.

Dogs who are pregnant or breastfeeding should not take Apoquel.

Research and Study:

Apoquel has been extensively researched and studied, with multiple clinical trials showing its effectiveness in treating atopic dermatitis in dogs.

Despite this, there is still much that is unknown about the long-term safety and effectiveness of the drug, and further research is ongoing.

Apoquel for dogs without a vet’s prescription

Apoquel is a prescription medication, so obtaining it without a vet’s approval is illegal. However, there are a few options for those who are unable to see a vet for various reasons.

Online pharmacies: There are online pharmacies that offer prescription drugs, including Apoquel, without the need for a physical examination. Just keep in mind that purchasing medications online can be risky, as it’s difficult to verify the authenticity of the product.

Compounding pharmacies: Compounding pharmacies can create custom medication formulas, including Apoquel, based on your dog’s specific needs. However, you will need to provide a prescription from a vet for them to do so.

Pet supply stores: Some pet supply stores offer a wide range of over-the-counter medications, but it’s unlikely that they will carry Apoquel.

If you’re unable to see a vet, it’s best to find alternative solutions for your dog’s skin conditions. There are natural remedies, such as omega-3 supplements, that may help relieve itching and inflammation.

Alternative to Benadryl and Apoquel

If you’re looking for a natural alternative to Benadryl or Apoquel for your furry friend, there are a few options worth considering.

First up, we have chamomile. This herb has been used for centuries to calm anxiety and soothe skin irritations. You can either brew a cup of chamomile tea for your dog to drink or apply a chamomile-infused oil directly to their skin.

Next, we have licorice root. This herb is often used to soothe digestive issues, but it also has anti-inflammatory properties that can help with skin irritations. You can give your dog licorice root extract or add it to their food.

If your pup is feeling a little hot under the collar, consider giving them some passionflower. This herb is well-known for its calming effects, making it a great alternative to Benadryl. You can give your dog passionflower extract or add it to their food.

Finally, we have omega-3 fatty acids. These fatty acids are essential for your dog’s overall health, but they also have anti-inflammatory properties that can help with skin irritations. You can give your dog fish oil supplements or add flaxseed oil to their food.

It’s always important to talk to your vet before trying any new remedies, but these natural alternatives to Benadryl and Apoquel are a good place to start.

FAQs about Benadryl vs Apoquel for dogs

We’ll answer some common questions about these medications to help you make an informed decision.

What is Benadryl?

Benadryl is a brand name for the drug diphenhydramine. It is an antihistamine that can be used to treat a variety of allergic reactions, including itching, swelling, and hives. Benadryl is available over the counter and is relatively inexpensive.

What is Apoquel?

Apoquel is a brand name for the drug oclacitinib. It is a prescription medication that is used to treat allergic skin reactions and itching in dogs. Apoquel works by blocking a specific enzyme in the body that causes itching and inflammation.

How do Benadryl and Apoquel differ?

The main difference between Benadryl and Apoquel is that Benadryl is an antihistamine, while Apoquel is a targeted immune modulator. This means that while Benadryl blocks the effects of histamine, Apoquel targets the specific enzyme that causes itching and inflammation.

Which medication is more effective?

Both Benadryl and Apoquel can be effective at treating allergic reactions and itching in dogs. However, Apoquel has been shown to be more effective in controlling itching and reducing inflammation in dogs with atopic dermatitis (a chronic skin condition caused by allergies) compared to Benadryl.

Are there any side effects to be aware of?

Both Benadryl and Apoquel can have side effects. Benadryl can cause drowsiness, dry mouth, and urinary retention. Apoquel can cause vomiting, diarrhea, and decreased appetite. It’s important to talk to your veterinarian about any potential side effects and to closely monitor your dog while they are taking either medication.

Can Benadryl and Apoquel be given together?

It is generally safe to give Benadryl and Apoquel together, but it’s important to talk to your veterinarian first. They may recommend adjusting the dosage or frequency of one or both medications to avoid potential side effects.

How long does it take for Benadryl and Apoquel to work?

Benadryl typically takes effect within 30 minutes to an hour after it is given, while Apoquel may take several hours to start working. It’s important to follow the dosing instructions provided by your veterinarian and to give the medication as directed to ensure maximum effectiveness.

Can Benadryl and Apoquel be used for long-term treatment?

Benadryl is generally considered safe for long-term use, but it may lose effectiveness over time as your dog’s body becomes accustomed to the medication. Apoquel is also safe for long-term use and may be a better option for dogs with chronic allergies or atopic dermatitis.

Can Benadryl and Apoquel be used for other conditions?

While Benadryl is primarily used to treat allergic reactions and itching, it may also be used to treat motion sickness, insomnia, and anxiety in dogs. Apoquel is only used to treat allergic skin reactions and itching and should not be used to treat other conditions.

Are there any alternatives to Benadryl and Apoquel?

There are several other medications that may be used to treat allergies and itching in dogs, including steroids, cyclosporine, and antihistamines such as cetirizine and fexofenadine. Your veterinarian can recommend the best treatment option for your dog based on their individual needs and medical history.

Can Benadryl and Apoquel be given to dogs of all ages?

Benadryl and Apoquel can be given to dogs of all ages, but the dosing may need to be adjusted for younger or older dogs. It’s important to talk to your veterinarian about the appropriate dosage for your dog based on their age, weight, and medical history.

Do I need a prescription to buy Benadryl or Apoquel?

Benadryl is available over the counter and does not require a prescription. Apoquel, on the other hand, is a prescription medication and can only be obtained through a veterinarian.

Can Benadryl and Apoquel be used for all types of allergies?

Benadryl and Apoquel can be used to treat allergic reactions caused by environmental allergens, such as pollen, mold, and dust mites. However, they may not be as effective at treating food allergies or flea allergies. Your veterinarian can recommend the best treatment option for your dog based on the type of allergy they are experiencing.

Is it safe to give Benadryl or Apoquel to pregnant or nursing dogs?

It’s generally not recommended to give Benadryl or Apoquel to pregnant or nursing dogs, as the effects of these medications on developing fetuses or newborn puppies are not fully understood. If your dog is pregnant or nursing and experiencing allergic reactions or itching, it’s important to talk to your veterinarian about alternative treatment options.

Can Benadryl or Apoquel be used in conjunction with other medications?

It’s important to talk to your veterinarian about any other medications or supplements your dog is taking before giving them Benadryl or Apoquel, as these medications can interact with other drugs. For example, Benadryl can interact with some antidepressants and blood pressure medications. Your veterinarian can recommend the best treatment plan for your dog based on their individual medical history.

Can Benadryl or Apoquel be used to treat flea infestations?

Benadryl and Apoquel are not effective at treating flea infestations. In addition to providing relief for itching and allergic reactions, it’s important to use a flea preventive medication to prevent future infestations.

Can I give my dog Benadryl or Apoquel without consulting a veterinarian?

While Benadryl is available over the counter and can be used to treat mild allergic reactions, it’s important to consult with a veterinarian before giving your dog any medication. Apoquel is a prescription medication and should only be used under the guidance of a veterinarian.

How often can I give my dog Benadryl or Apoquel?

The dosing frequency for Benadryl and Apoquel can vary depending on your dog’s individual needs and medical history. It’s important to follow the dosing instructions provided by your veterinarian and to not exceed the recommended dose. Overdosing on these medications can cause serious side effects.

Can Benadryl or Apoquel be given with food?

Benadryl and Apoquel can be given with or without food. However, giving these medications with food may help reduce the risk of stomach upset.

Can Benadryl or Apoquel be given to dogs with liver or kidney disease?

Benadryl and Apoquel should be used with caution in dogs with liver or kidney disease, as these medications can affect liver and kidney function. It’s important to consult with a veterinarian before giving these medications to a dog with liver or kidney disease.

Can Benadryl or Apoquel be given to dogs with other health conditions?

Benadryl and Apoquel can be used to treat allergic reactions and itching in dogs with other health conditions, but the dosing may need to be adjusted based on the dog’s medical history. For example, dogs with heart disease or high blood pressure may need a lower dose of Benadryl to avoid negative effects on their cardiovascular system.