Is There a Generic for Apoquel? 10 Alternatives

Apoquel is an effective medication for treating allergies in dogs, but its high cost and lack of a generic version can be a concern for pet owners. In this article, we will discuss more affordable alternatives to Apoquel that can still help alleviate your dog’s allergy symptoms, making both you and your furry friend happier.

1. Over-the-counter Antihistamines

One of the more cost-effective alternatives to Apoquel is over-the-counter antihistamines, such as Zyrtec (Cetirizine) and Benadryl (Diphenhydramine). These medications can help reduce itching, swelling, and redness caused by allergies in dogs. Consult with your veterinarian for the appropriate dosage and frequency before administering these medications to your dog.

2. Fatty Acid Supplements

Adding Omega-3 fatty acid supplements to your dog’s diet can help improve skin health and reduce inflammation caused by allergies. Fish oil supplements are an excellent source of Omega-3 fatty acids and can be easily found at pet stores and online retailers. Always follow the recommended dosage and consult your veterinarian if you have any concerns.

3. Natural Topical Treatments

For dogs with localized itching or skin irritation, natural topical treatments like aloe vera gel, coconut oil, or calendula cream can provide relief. These products can be applied directly to the affected areas and can help soothe and heal the skin. However, it is essential to monitor your dog closely to ensure they do not ingest the product.

4. Probiotics

A healthy gut can contribute to a healthier immune system, which in turn can help reduce allergy symptoms. Adding a probiotic supplement to your dog’s diet can help maintain a balanced gut microbiome, potentially reducing the severity of their allergies. Always choose a high-quality probiotic specifically designed for dogs and follow the recommended dosage.

5. Hydrolyzed Protein Diets

For dogs with food allergies, a hydrolyzed protein diet can be an effective alternative to Apoquel. Hydrolyzed protein diets break down proteins into smaller peptides, making them less likely to trigger an allergic reaction. Consult your veterinarian for the best hydrolyzed protein diet options for your dog.

6. Cytopoint Injections

While not necessarily cheaper than Apoquel, Cytopoint injections can provide long-lasting relief from itchiness caused by allergies. Cytopoint works by targeting and neutralizing the specific proteins responsible for causing itchiness in dogs. This treatment is administered by your veterinarian and can provide relief for up to 4-8 weeks per injection.

7. Quercetin Supplements

Quercetin is a natural antioxidant found in fruits and vegetables that can help alleviate allergy symptoms in dogs. This bioflavonoid has anti-inflammatory properties and can be used as a supplement to reduce itching and inflammation caused by allergies. When choosing a quercetin supplement for your dog, ensure it is formulated specifically for pets and follow the recommended dosage guidelines.

8. Oatmeal Baths

Oatmeal baths are a soothing, natural way to provide relief for your dog’s itchy and irritated skin. To prepare an oatmeal bath, simply grind plain, uncooked oats into a fine powder and mix with warm water. Gently massage the oatmeal mixture onto your dog’s skin and let it sit for about 10 minutes before rinsing thoroughly. This treatment can be repeated as needed to help alleviate discomfort.

9. Apple Cider Vinegar

Apple cider vinegar is a versatile natural remedy that can help soothe your dog’s itchy skin when applied topically. Mix equal parts apple cider vinegar and water, and gently dab the solution onto the affected areas using a clean cloth. Be cautious when using apple cider vinegar around open wounds, as it can cause stinging.

10. Allergy Testing and Immunotherapy

If your dog’s allergies persist despite trying various treatments, consult your veterinarian about allergy testing. Identifying the specific allergens affecting your dog can help tailor treatment plans more effectively. In some cases, immunotherapy (allergy shots) can be a long-term solution to desensitize your dog to the allergens causing their symptoms.


Can Apoquel be used with other medications?

Apoquel can generally be used alongside other medications, but it is crucial to consult your veterinarian before combining treatments. They will consider your dog’s specific medical history, the medications they are currently taking, and any potential interactions that could occur.

How long does it take for Apoquel to start working?

Apoquel begins to work quickly, providing relief from itching within 4 hours of administration. Maximum efficacy is usually achieved within 24 hours. However, individual responses may vary, and it is essential to monitor your dog closely when starting a new medication.

How long can a dog stay on Apoquel?

Apoquel can be used for both short-term and long-term treatment of canine allergies. The duration of treatment will depend on your dog’s specific condition, response to the medication, and your veterinarian’s recommendations. Regular check-ups with your veterinarian are essential for monitoring your dog’s progress and adjusting the treatment plan as needed.

Are there any side effects of Apoquel?

While Apoquel is generally well-tolerated by dogs, some potential side effects may include vomiting, diarrhea, lethargy, and decreased appetite. If your dog experiences any adverse effects or if their symptoms worsen, consult your veterinarian immediately.

Can I use home remedies to treat my dog’s allergies?

Home remedies, such as oatmeal baths, apple cider vinegar, and coconut oil, can provide temporary relief for mild allergy symptoms. However, they may not be as effective as prescription medications like Apoquel for severe or persistent allergies. It is essential to consult your veterinarian to determine the best course of treatment for your dog’s specific needs.

Can a change in diet help alleviate my dog’s allergy symptoms?

A change in diet may help alleviate allergy symptoms in dogs with food allergies. Your veterinarian may recommend a hydrolyzed protein diet or a limited ingredient diet to determine if food allergies are contributing to your dog’s symptoms. Always consult your veterinarian before making any changes to your dog’s diet.

How do I know if my dog’s allergy symptoms are improving?

Monitoring your dog’s symptoms and overall well-being is crucial for determining if their allergy treatment is effective. Look for a decrease in itching, redness, and skin irritation, as well as improvements in your dog’s overall comfort and behavior. Regular check-ups with your veterinarian can also help assess your dog’s progress and adjust the treatment plan as needed.

Can I give my dog human allergy medications?

While some human allergy medications, such as Benadryl or Zyrtec, can be used for dogs under a veterinarian’s guidance, it is essential to consult your vet before administering any human medications to your dog. Dosage and formulations may differ between humans and dogs, and some human medications may be harmful or even toxic to dogs.

Is Apoquel a steroid?

Apoquel is not a steroid. It is a selective Janus kinase (JAK) inhibitor that works by targeting specific enzymes responsible for causing itching and inflammation related to allergies in dogs. Apoquel provides relief without the long-term side effects typically associated with steroid use.

Can Apoquel cause weight gain in dogs?

Apoquel is not known to cause significant weight gain in dogs. However, if you notice any changes in your dog’s weight or appetite while taking Apoquel, consult your veterinarian for further evaluation and guidance.

What should I do if my dog misses a dose of Apoquel?

If your dog misses a dose of Apoquel, give the missed dose as soon as you remember. If it is close to the time for the next dose, skip the missed dose and continue with the regular dosing schedule. Do not give a double dose to make up for the missed dose. If you are unsure about what to do, consult your veterinarian for advice.

Can Apoquel be used for other skin conditions?

Apoquel is primarily prescribed for the treatment of allergies and related itching in dogs. While it may provide some relief for other skin conditions, it is essential to consult your veterinarian to determine the best course of action for your dog’s specific condition. A thorough evaluation by your vet will help identify the underlying cause and develop an appropriate treatment plan.

How should I store Apoquel?

Apoquel should be stored at room temperature, away from moisture, heat, and direct sunlight. Keep the medication in its original packaging, and always store it out of reach of children and pets.

Can Apoquel be used for cats?

Apoquel is not approved for use in cats. It has been specifically developed and tested for the treatment of allergies and related itching in dogs. If your cat is experiencing allergies or skin issues, consult your veterinarian for a proper evaluation and recommendation of appropriate treatments for feline patients.

What precautions should I take when handling Apoquel?

When handling Apoquel, follow standard safety precautions, such as washing your hands after administering the medication and keeping it away from children and pets. If you are pregnant or nursing, consult your healthcare provider for guidance on handling Apoquel or any other medications.

Can I stop giving Apoquel to my dog once their symptoms improve?

It is essential to follow your veterinarian’s instructions regarding the duration of treatment with Apoquel. Stopping the medication abruptly may cause your dog’s symptoms to return or worsen. If you believe your dog no longer requires Apoquel, consult your veterinarian to discuss a suitable plan for tapering the medication or transitioning to an alternative treatment.

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