Metronidazole Dosing Chart for Dogs

Metronidazole is a powerful medication used to treat various bacterial and parasitic infections in dogs. The standard dose ranges between 4.5 to 6.8 mg per pound of body weight and is usually given every 12 hours for a period of seven days. However, it’s essential to note that the actual dose and duration of treatment may vary depending on the severity of the infection and your veterinarian’s recommendations.

Metronidazole dosage for dogs chart

Metronidazole dosage for dogs calculator

Dog’s weight (lbs) Metronidazole dosage (compounded capsule)
10 to 20 lbs 1 capsule of 100 mg
21  to 30 lbs 1 capsule of 150 mg
31 to 40 lbs 1 capsule of 200 mg
41 to 50 lbs 1 capsule of 250 mg
51 to 60 lbs 1 capsule of 300 mg
61 to 70 lbs 1 capsule of 350 mg
71 to 90 lbs 1 capsule of 400 mg

It’s always a good idea to consult with a veterinarian before starting any medication, especially if your furry friend has any underlying health conditions or is taking any other medications. This way, they can assess the best course of action and provide you with a customized dose chart to ensure your pup is getting the right amount of medicine.

Now, here’s the thing to keep in mind – it’s crucial to not exceed the recommended dose as it can lead to toxic effects, especially in the nervous system. So, make sure you follow the instructions carefully and measure out the proper amount of medication before administering it to your pup.

Metronidazole for dogs reviews


Metronidazole is commonly prescribed for the treatment of skin, intestinal, and respiratory infections caused by bacteria and parasites such as Giardia and Clostridium. It is also used to treat anaerobic infections, which are infections caused by bacteria that thrive in low-oxygen environments.


  • Effective treatment for a wide range of infections in dogs
  • Can be administered orally or topically
  • Has a relatively low cost compared to other medications
  • Can be used in combination with other antibiotics for more comprehensive treatment


  • May cause digestive upset, including nausea, vomiting, and diarrhea
  • Can have negative interactions with other medications, especially anticoagulants
  • Can cause liver and neurological side effects if used in high doses or for prolonged periods
  • May cause skin irritations or allergic reactions

Side effects:

Common side effects of Metronidazole in dogs include digestive upset, lack of appetite, and lethargy. In severe cases, it can cause liver and neurological problems such as seizures, ataxia, and changes in behavior. It is important to report any side effects to your vet as soon as possible.


Metronidazole is generally safe for use in dogs when administered in appropriate doses. However, it is toxic to cats and should never be used in felines. Overdose or prolonged use of Metronidazole can also lead to toxicity in dogs.

Drug interactions:

Metronidazole can interact with a number of other medications, including anticoagulants, antidepressants, and seizure medications. It is important to inform your vet of all medications your dog is currently taking to avoid potential negative interactions.


Metronidazole should not be used in pregnant or lactating dogs, as it can cause harm to the developing fetus or puppies. It should also be avoided in dogs with a history of liver or neurological problems.

Research and study:

Metronidazole has been extensively researched and studied for its efficacy in treating various bacterial and parasitic infections in dogs. The results of these studies have shown it to be a safe and effective option for treatment.


There are several alternative medications available for the treatment of bacterial and parasitic infections in dogs, including amoxicillin, ciprofloxacin, and doxycycline. Your vet will be able to recommend the best option for your dog based on their specific condition and medical history.

What are the side effects of Metronidazole in dogs?

First and foremost, one of the most common side effects of Metronidazole in dogs is gastrointestinal upset. This can manifest in several ways, such as vomiting, diarrhea, loss of appetite, and even abdominal pain. If your dog is showing any of these symptoms after taking Metronidazole, it’s important to reach out to your vet.

Another side effect that is worth mentioning is neurological issues. This can include disorientation, confusion, seizures, and even tremors. If you notice any changes in your dog’s behavior or movement after taking Metronidazole, it’s important to seek veterinary attention right away.

Additionally, some dogs may also experience an allergic reaction to Metronidazole. This can include itching, hives, swelling, and even difficulty breathing. If you suspect your dog is having an allergic reaction, you should contact your vet immediately.

Lastly, it’s worth mentioning that Metronidazole can cause liver and kidney damage in some dogs. This is a rare side effect, but it’s important to be aware of it nonetheless. If your dog is showing any symptoms of liver or kidney failure, such as yellowing of the skin and eyes, increased thirst and urination, or lethargy, it’s important to seek veterinary attention.

How long should I give my dog metronidazole?

When it comes to dosing your furry friend with metronidazole, it’s important to follow your vet’s instructions to a tee. But, generally speaking, the length of time you should give your dog metronidazole depends on the specific condition it’s being used to treat.

For instance, if your pup has an upset tummy or is dealing with diarrhea, metronidazole is usually given for 5 to 10 days. On the other hand, if it’s being used to treat a more serious condition like periodontal disease or a bacterial infection, you may need to give it to your dog for several weeks.

Note that metronidazole can cause some side effects, like loss of appetite, nausea, and vomiting, so it’s best to start with smaller doses and gradually increase as directed by your vet.

In short, the duration of metronidazole treatment will vary, but it’s crucial to follow your vet’s advice and keep an eye on your pup for any adverse reactions. It’s always better to be safe than sorry, right?

How much metronidazole is toxic for dogs?

According to veterinary experts, the threshold for metronidazole toxicity in dogs is 27 mg per pound of body weight. That’s the dose at which clinical signs of central nervous system depression start to appear.

Acute high-dose exposures to metronidazole can lead to serious problems, such as hepatic necrosis, which is damage to the liver. And even with treatment, death may occur in severe cases. That’s why it’s crucial to follow the instructions of your veterinarian and never exceed the recommended dose for your dog’s weight.

Can a dog recover from metronidazole toxicity?

The good news is, yes, a dog can recover from metronidazole toxicity, but it’s important to act quickly and seek veterinary care.

If a dog ingests too much of it, it can result in toxicity. The symptoms of metronidazole toxicity include vomiting, loss of appetite, diarrhea, and lethargy. In severe cases, it can cause neurological problems such as seizures, tremors, and even coma.

If you suspect that your dog has consumed an excessive amount of metronidazole, don’t wait to seek veterinary care. Time is of the essence, as early treatment can increase the chances of a successful recovery.

The veterinarian may induce vomiting to remove the drug from the dog’s system and prescribe medications to treat the symptoms of toxicity. In severe cases, the dog may need to be hospitalized and receive intravenous fluids and other treatments.

Remember that every dog is different, and the recovery time can vary based on the severity of the toxicity. In most cases, a dog will recover from metronidazole toxicity within a few days with proper treatment. However, if the toxicity is severe, it could take a few weeks for the dog to fully recover.

In conclusion, if your dog has consumed too much metronidazole, don’t panic. With prompt veterinary care, most dogs can make a full recovery from metronidazole toxicity. Just like us, dogs can bounce back from illness, and with a little TLC, they’ll be back to their waggy-tailed selves in no time.

FAQs about metronidazole dose for dogs chart

What is metronidazole, and how does it work for dogs?

Metronidazole is an antibiotic that is used to treat a range of bacterial and parasitic infections in dogs. It works by penetrating the bacteria or parasite’s cell wall and inhibiting its ability to replicate.

How much metronidazole should I give my dog?

The dosage of metronidazole for dogs depends on the dog’s weight, age, and the severity of the infection. Typically, the dosage ranges from 5-25 mg per pound of the dog’s body weight per day, divided into two to three doses.

How long should I give metronidazole to my dog?

The duration of metronidazole treatment varies depending on the type of infection and the severity of the symptoms. Generally, treatment lasts for seven to ten days, but in some cases, it may last up to 14 days.

Can I give my dog metronidazole with food?

Yes, you can give your dog metronidazole with or without food. However, giving it with food can help reduce the chances of gastrointestinal upset.

What are the side effects of metronidazole?

The common side effects of metronidazole in dogs include vomiting, diarrhea, lack of appetite, and lethargy. In rare cases, it may cause liver toxicity or neurological symptoms, such as seizures or disorientation. If you observe any of these symptoms, contact your veterinarian immediately.

Can I give metronidazole to a pregnant dog?

Metronidazole is safe for pregnant dogs, but it should be given only under a veterinarian’s supervision.

What should I do if I miss a dose of metronidazole?

If you miss a dose of metronidazole, give it as soon as you remember. However, if it is close to the next dose, skip the missed dose and continue with the regular dosing schedule.

Can I crush metronidazole tablets and mix them with food?

Yes, you can crush metronidazole tablets and mix them with your dog’s food. However, make sure to mix it well to ensure your dog consumes the full dose.

Can I stop metronidazole treatment once my dog’s symptoms disappear?

No, you should not stop metronidazole treatment once your dog’s symptoms disappear. It is essential to complete the full course of medication as prescribed by your veterinarian to ensure that the infection is completely eradicated.

How should I store metronidazole?

Metronidazole should be stored at room temperature and away from moisture and direct sunlight. Additionally, make sure to keep it out of reach of children and pets.

Can I give my dog metronidazole if he is on other medications?

Metronidazole can interact with certain medications, so it is essential to inform your veterinarian if your dog is taking any other medications. They can advise you on the appropriate dosage and timing of metronidazole in conjunction with other medications.

Can I give metronidazole to my puppy?

Metronidazole is safe for puppies, but it should be given only under a veterinarian’s supervision.

What should I do if my dog experiences an allergic reaction to metronidazole?

If your dog experiences an allergic reaction to metronidazole, such as difficulty breathing, swelling of the face or lips, or hives, seek emergency veterinary care immediately.


Hannah Elizabeth is an English animal behavior author, having written for several online publications. With a degree in Animal Behaviour and over a decade of practical animal husbandry experience, Hannah's articles cover everything from pet care to wildlife conservation. When she isn't creating content for blog posts, Hannah enjoys long walks with her Rottweiler cross Senna, reading fantasy novels and breeding aquarium shrimp.

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